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cells PhD Projects, Programmes & Scholarships
We have 677 cells PhD Projects, Programmes & Scholarships
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The role of extracellular vesicles in lung epithelial cell communication in health and disease
It is estimated that more than 1 bn people suffer from acute and chronic lung problems resulting in millions of deaths every year. Read more
Survival of Cancer Stem Cells: a good opportunity in bad neighbourhood
Cancers are not just masses of malignant cells but complex ‘rogue’ organs, to which many other cells are recruited and can be corrupted. Read more
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Understanding the pro- and anti-tumour functions of IFNγ-producing γδ T cells
TO APPLY CLICK 'INSTITUTION WEBSITE' . γδ T cells are a rare population of T cell receptor-expressing cells that function like innate immune cells.γδ T cells consist of several different subtypes that can promote or prevent cancer progression, depending on the cytokines and cytotoxic molecules they express. Read more
Single-Cell Lineage Mapping of Elite CAR-NK Cells
The advance of chimeric antigen receptor (CAR) technology has been a breakthrough in cancer immunotherapy. However, it is not clear in which subpopulation of immune cells the endowment of CAR will be most effective in treating cancer. Read more
4-year PhD Studentship: Targeting cancer stem cells: Selective culture method and drug search
Cancer stem cells are a small population of cells in tumours maintaining the tumorigenic capacity (1). They are featured as quiescent (i.e., dormant), in contrast to the majority of cancer cells that actively proliferate under the aberrant regulation. Read more
Normal and leukaemic stem/progenitor cell biology and immune responses to blood cancer cells.
Blood cell differentiation is one of the best characterised models to study how normal tissue-specific stem cells give rise to diverse cell types. Read more
Normal and leukaemic stem/progenitor cell biology and immune responses to blood cancer cells.
Blood cell differentiation is one of the best characterised models to study how normal tissue-specific stem cells give rise to diverse cell types. Read more
MSc by Research: Regulation of T cell function by SIK3 in viral infection
T cells play critical roles in the host response to viral infection. Activated cytotoxic CD8 T cells are able to kill virally infected cells while… Read more
Preferential Gq signalling in diabetes: an electrical switch in incretin action and in diabetes progression?
The progression of type 2 diabetes (T2D) involves development of insulin resistance that is frequently associated with obesity and that is initially compensated by increased insulin secretion from pancreatic β-cells. Read more
An interdisciplinary approach to tackling the problem of late Myeloma diagnosis.
There are two parallel studentships on offer. One (this project) is a wet lab project and the other is a bioinformatics project. Both are addressing the fact that multiple myeloma (MM) (a blood cancer of antibody producing cells) is nearly always diagnosed late. Read more
Can the natural health supplement Fisetin reverse senescence in vascular cells?
Cellular senescence is a mechanism that is activated in stressed cells to prevent the replication of damaged DNA. Senescent cells are found in vessel walls as well as in other tissues and have been shown to play a role in ageing and age-related diseases such as cardiovascular disease. Read more
Characterisation of the role of Panx1/Panx2 in primary endothelial cells
Pannexins are a family of proteins that are evolutionary related to the gap-junction forming proteins, innexins (1). Three members have been identified, Panx1, Panx2 and Panx3, and they show distinct tissue distribution. Read more
Using microfluidics and flow cytometry to develop novel diagnostics for Leishmaniasis
The Leishmaniases are a group of neglected tropical diseases caused by >20 species of Leishmania parasites that are spread by >90 species of phlebotomine sand flies. 1 billion people in Africa, Asia, the Americas and the Mediterranean are at risk, with the poor and malnourished being disproportionately affected. Read more
Inter- and intra-cellular signalling in the development of fibrosis in the hypertensive heart
Project Overview. Heart failure is a leading cause of morbidity and mortality worldwide. In terms of volume, the normal heart is composed mostly of terminally-differentiated contractile cells (cardiomyocytes), responsible for the pump action of the heart. Read more
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Roles for “persister” cells in drug treatment failure in Leishmania
It has become clear in recent years that bacterial pathogens, within their mammalian hosts, can enter a quiescent state where metabolism is partially switched… Read more