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cells PhD Projects, Programmes & Scholarships
We have 744 cells PhD Projects, Programmes & Scholarships
Funded PhD- Exploring the modulation of Antioxidant Metabolism to target Adult T-Cell Leukaemia Induced by HTLV-1 Infection
One potential approach to eliminating HTLV-1 infected cells is based on the evidence that retroviral infection can cause cellular metabolic dysregulation. Read more
(MRC DTP) Computational and experimental strategies for optimising the generation of human therapeutic relevant cells
Blood transfusions, bone marrow stem cell transplants, and immunotherapies are essential in treating cancer and various other diseases. Read more
Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype
Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more
Resident memory B cell responses in the lung; immunity against pulmonary pathogens
Immunological memory of antibody responses is critical for the ability of the host to cope with secondary infections and is the basis for the development of most current vaccines. Read more
PhD Opportunity - Using microfluidics and flow cytometry to develop novel diagnostics for Leishmaniasis
'TO APPLY, PLEASE CLICK INSTITUTION WEBSITE'. Summary. Read more
Funded PhD- Investigating the mechanisms underlying Professional killer cell dysfunction in dengue
Background & preliminary data. Dengue virus (DENV) co-circulates as four serotypes (DENV1-4) and causes symptoms ranging from uncomplicated febrile illness to lifethreatening severe dengue (SD) characterized by plasma leakage, haemorrhage and hypovolemic shock. Read more
Haematology: Oncogenic mechanisms causing malignant transformation of B cells and plasma cells
Cancers of B cells and plasma cells, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Read more
Development of Novel Cellular Platforms for Immunotherapies
Blood transfusions, bone marrow stem cell transplants, and immunotherapies are fundamental procedures in the treatment of malignant and non-malignant disorders. Read more
Defining MR1-ligand expression in human and mouse tissues
Commercial partner: Immunocore. MR1 (MHC Related Molecule 1) is an important immunologic molecule that presents ligands to unconventional T cells. Read more
(MCRC Non-clinical) Do chromatin remodellers control awakening of hibernating cancer cells?
Cancer cells adapt to live in the presence of treatment or any selective pressure. This sometimes leads to cancer cells hibernating and lingering in the host tissues by stopping cell division. Read more
Exploring chemoprevention: Investigating the impact of novel Endocrine Disrupting Chemicals (EDCs) on breast cells and onset of tumours using a Body-on-a-chip model
Research Group:
Institute of Cancer Therapeutics
Endocrine-disrupting compounds (EDCs) are a group of chemicals that can alter the normal functioning of the body’s hormonal system and can have harmful effects. Read more
Creating microcarriers for improving the survival and integration of cells transplanted to the brain.
Background. For neurodegenerative diseases such as Parkinson’s disease, where a specific cell type is lost, it is possible to consider replacing these cells to restore the lost function. Read more
Investigating how dormant senescent cells can drive drug-resistance following chemotherapy
Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more
Exploring the role of interferon stimulated genes (ISGs) in stem cells of serous ovarian cancer
Research Group:
Institute of Cancer Therapeutics
Epithelial ovarian cancer (EOC) is the leading cause of mortality in women due to gynaecological cancers. High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of patients with EOC. Read more
(MRC DTP) Determining the role of the inositol phosphatase INPP5B in adaptive immunity
The adaptive immune system is fundamentally important, protecting us from a multitude of pathogens. Read more