Continue with FacebookLooking to list your PhD opportunities? Log in here.
chromatin PhD Projects, Programmes & Scholarships
We have 34 chromatin PhD Projects, Programmes & Scholarships
PhD saved successfully
The role of non-coding RNAs and epitranscriptomics in shaping 3D chromatin architecture in stem cells.
We are looking for an enthusiastic PhD student interested in working on non-coding RNAs and chromatin architecture at the Center for Human Technologies @IIT (Genova-Italy). Read more
Evaluation of MCT1s role in chromatin remodelling and metabolomics changes involved in cancer progression
Monocarboxylate transporter 1 (MCT1) is a transmembrane protein involved in cell metabolism and mediates transport of monocarboxylates (such as pyruvate {a metabolic substrate} and lactate {a metabolic by product}) in and out of the cell. Read more
Diversifying the histone code: defining the role of non-canonical phosphorylation in chromatin structure
This opportunity will remain open until the position has been filled. Post-translational modifications (PTMs) of histones are known to direct chromatin structure and thus gene transcription. Read more
Combined in vitro and in silico molecular analysis of CHD8 gene-mediated risk for ASD
Aim. To understand the molecular mechanisms by which mutation of the CHD8 gene increases risk of Autism Spectrum Disorder (ASD). Background. Read more
The links between chromatin organization, microtubule dynamics and tumor cell migration
We are seeking for a highly motivated PhD students to study the links between chromatin organization and microtubule dynamics or/and tumor cell migration. Read more
MSc by Research: Investigating the tumor suppressor functions of chromatin remodelling
One of the unanticipated outcomes of population based genome sequencing has been the finding that genes involved in the regulation of many genes are mutated at high frequency in tissue specific cancers. Read more
Revealing epigenetic signaling mechanisms in genome regulation and cancer.
We are looking for highly motivated PhD students to join our efforts to reveal epigenetic mechanisms that regulate the function of eukaryotic genomes in health and disease. Read more
Chromatin dynamics regulating light and temperature signalling in Arabidopsis
Outline & Aim. Environmental and endogenous stimuli shape plant development, growth and photoprotection by triggering nuclear processes that lead to major changes in gene expression. Read more
Exploring the transcriptomic and chromatin landscapes of fibroblast-like synoviocytes in rheumatoid arthritis
Genetic studies in rheumatoid arthritis (RA) have been successful in identifying regions of the genome which contribute to disease risk, but it is often unclear which genes they effect. Read more
Understanding gene regulation by HDAC1 complexes in development and cancer
Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more
3D genome folding and its role in DNA-based processes
The organization of genomic DNA into chromatin fibres and nucleosomes and their regulation by histone modifications is well understood, as is the relevance of these mechanisms for gene regulation. Read more
Long noncoding RNA control of Drosophila Hox gene expression
Variation in gene regulation between animals often explains differences between species and individuals, and perturbed gene expression frequently underlies disease states. Read more
Mechanisms of gene regulation shared between human development and neurodegeneration
Applications are invited for a research studentship leading to the award of a PhD degree, under the supervision of Dr. Marco Trizzino, to investigate mechanisms of gene regulation shared between human development and neurodegeneration. Read more
Defining the Epigenome in Tendon Ageing
University of Liverpool
Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
One hallmark of ageing is the accumulation of epigenetic alterations. There is a clear link between age and increasing incidence of tendon injury suggesting that the mechanical integrity of tendon declines with age. Read more
Discovery and mechanism evaluation of synthetic lethality in cancers of mesenchyme
In order to circumvent evolutionary selection and resistance to environmental context and anti-cancer agents, novel approaches that result in synthetic (synergistic) cell lethality (dependencies) that are specific for the cancer cell are most likely to have translational impact. Read more
