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chromatin PhD Projects, Programs & Scholarships

We have 79 chromatin PhD Projects, Programs & Scholarships

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  Chromatin and maintenance of genome stability
University of Bristol School of Biochemistry
  Dr A Chambers
Applications accepted all year round
Within eukaryotes, DNA is packaged into chromatin. The basic unit of chromatin is the nucleosome, formed by the wrapping of ~147 bp of DNA around an octamer of histones proteins.
Details
Type/Funding
  ChromDesign-ITN: Chromatin topology studies in mouse ES and human leukemia cell lines (subproject ESR13); Hosting institution: Diagnose, Liege, Belgium
Centre for Genomic Regulation (CRG) Gene Regulation, Stem Cells and Cancer
  Dr Celine Sabatel, Prof MariaElena orres-Padilla
Application Deadline: 21 December 2018
"ChromDesign” is a European innovative and interdisciplinary Research and Training network, which aims to characterize the impact of the 3D chromatin organization on gene regulation during cellular differentiation and in several human disorders, and to train junior researchers in the biomedical field, either in academia or in the private sector.
Details
Type/Funding
  Chromatin remodelling in health and disease: determining the role of ATRX in the maintenance of chromatin and how mutations perturb disparate nuclear nuclear processes and lead to human disease
University of Oxford Radcliffe Department of Medicine
  Dr R Gibbons, Prof D Higgs
Application Deadline: 11 January 2019
It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
Details
Type/Funding
  Investigating the Drosophila DF31 protein to gain insight into the mechanisms and chromatin maintenance in animal cells
St George’s, University of London Molecular and Clinical Sciences Research Institute
  Dr S Cotterill, Dr A Nohturfft
Applications accepted all year round
The Drosophila DF31 protein is an abundant ribonucleoprotein that localises to euchromatic regions and is involved in maintaining chromosome structure.
Details
Type/Funding
  How does nucleosome remodelling silence chromatin?
University of Leicester Molecular and Cell Biology
  Dr T Schalch, Dr S Cowley
Application Deadline: 6 January 2019
Regulation of transcription through chromatin architecture is governed by nucleosome remodelers and is essential in establishing the transcriptional programs of eukaryotic cells, which underpin survival, cellular identity and many disease states.
Details
Type/Funding
  ChromDesign-ITN: Progression of 3D genome folding in neurons during ageing (subproject ESR9); Hosting institution: EMBL - European Molecular Biology Laboratory, Heidelberg, Germany
Centre for Genomic Regulation (CRG) Gene Regulation, Stem Cells and Cancer
  Prof Edith Heard, Prof G Cavalli
Application Deadline: 21 December 2018
"ChromDesign” is a European innovative and interdisciplinary Research and Training network, which aims to characterize the impact of the 3D chromatin organization on gene regulation during cellular differentiation and in several human disorders, and to train junior researchers in the biomedical field, either in academia or in the private sector.
Details
Type/Funding
  Profiling stem cell epigenetic transitions within the Drosophila hematopoietic stem cell niche
University of Birmingham Institute of Immunology and Immunotherapy
  Dr P Badenhorst, Prof C Bonifer
Applications accepted all year round
The self-renewal and differentiation of stem cells is controlled by signals derived from the microenvironment or “niche”. The paired hematopoietic organs of the Drosophila genetic model organism are a well-characterized system in which the regulation of stem cell behaviour within a niche can be genetically dissected.
Details
Type/Funding
  ChromDesign-ITN: Detection of abnormal chromatin interaction in patient fibroblasts (subproject ESR10); Hosting institution: Max Planck Institute for Molecular Genetics, Berlin, Germany
Centre for Genomic Regulation (CRG) Gene Regulation, Stem Cells and Cancer
  Prof S Mundlos, Prof G Cavalli
Application Deadline: 21 December 2018
"ChromDesign” is a European innovative and interdisciplinary Research and Training network, which aims to characterize the impact of the 3D chromatin organization on gene regulation during cellular differentiation and in several human disorders, and to train junior researchers in the biomedical field, either in academia or in the private sector.
Details
Type/Funding
  PhD project on Epigenetic Mechanisms in Neuroscience: uncovering the role of three dimensional chromatin organization
Bar-Ilan University Faculty of Medicine
  Dr E Elliott
Applications accepted all year round
We are seeking an enthusiastic student for a novel project on the epigenetic basis of behavior. The goal of the project, under the direct supervision of Dr.
Details
Type/Funding
  Transcriptional programming of chromatin in normal and malignant haematopoiesis
University of Birmingham Institute of Cancer and Genomic Sciences
  Prof C Bonifer
Applications accepted all year round
In our work, we address the question of how the regulators of transcription, the sequence-specific DNA binding proteins or transcription factors, interact with the chromatin template and change its structure.
Details
Type/Funding
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