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chromatin PhD Projects, Programs & Scholarships

We have 43 chromatin PhD Projects, Programs & Scholarships

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  Is epigenetic information is exchanged between sister chromatids to restore chromatin structure and maintain epigenetic information after DNA replication?
  Dr N Francis
Applications accepted all year round

Funding Type

PhD Type

DNA in eukaryotic cells is organized into chromatin. Far from being an inert packing material, chromatin is a rich source of information for gene regulation.
  Chromatin remodelling in health and disease
  Dr R Gibbons, Prof D Higgs
Application Deadline: 24 July 2020

Funding Type

PhD Type

It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
  Chromatin remodelling in health and disease
  Dr R Gibbons, Prof D Higgs
Application Deadline: 24 July 2020

Funding Type

PhD Type

It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
  Tumor-promoting roles of the chromatin-associated DEK oncogene in metastatic melanoma
  Dr F Kappes, Prof C Eyers
Applications accepted all year round

Funding Type

PhD Type

The candidate should have a master’s degree (or equivalent qualification) in biochemistry, cell biology or a life-science related discipline.
  MSc by Research Programme: Investigating the tumor suppressor functions of chromatin remodelling
  Prof T A Owen-hughes
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  The role of phase separation in epigenetic inheritance by Polycomb Group proteins.
  Dr N Francis
Applications accepted all year round

Funding Type

PhD Type

In recent years, the role of phase separation in organizing macromolecules in cells is increasingly appreciated. This includes the organization of chromatin into physical and functional domains.
  Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
  Prof E D Laue
Applications accepted all year round

Funding Type

PhD Type

The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells.
  Revealing molecular mechanisms of gene silencing
  Dr T Schalch, Dr S Cowley
Application Deadline: 7 June 2020

Funding Type

PhD Type

Regulation of transcription through chromatin architecture is governed by nucleosome remodelers and chromatin modifying complexes.
  Novel non-coding RNAs in Drug response, DNA Damage and Aging
  Dr A Kanhere
Applications accepted all year round

Funding Type

PhD Type

Background. One of the biggest surprises of human genomic sequencing was the finding that only ~2% of the genome codes for proteins.
  Computational Functional Genomics
  Assoc Prof G Lunter
Application Deadline: 24 July 2020

Funding Type

PhD Type

We are interested in building computational models to understand and predict the functional consequences of mutations in the (human) genome.
  Laboratory of Gene Regulation
  Prof D Higgs, Prof J Hughes, Dr R Gibbons, Dr V Buckle
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation.
  Computational Functional Genomics
  Assoc Prof G Lunter
Application Deadline: 24 July 2020

Funding Type

PhD Type

We are interested in building computational models to understand and predict the functional consequences of mutations in the (human) genome.
  Laboratory of Gene Regulation
  Prof D Higgs, Prof J Hughes, Dr R Gibbons, Dr V Buckle
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation.
  Exploring the transcriptomic and chromatin landscapes of fibroblast-like synoviocytes in rheumatoid arthritis
  Dr S Eyre, Mr P Martin, Dr AM Morris
Applications accepted all year round

Funding Type

PhD Type

Genetic studies in rheumatoid arthritis (RA) have been successful in identifying regions of the genome which contribute to disease risk, but it is often unclear which genes they effect.
  Understanding the gene regulatory landscape of embryonic stem cells and cancer cells
  Prof A Sharrocks, Prof M Rattray
Applications accepted all year round

Funding Type

PhD Type

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity.
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