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chromatin PhD Projects, Programs & Scholarships

We have 28 chromatin PhD Projects, Programs & Scholarships

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  Chromatin and maintenance of genome stability
  Dr A Chambers
Applications accepted all year round

Funding Type

PhD Type

Within eukaryotes, DNA is packaged into chromatin. The basic unit of chromatin is the nucleosome, formed by the wrapping of ~147 bp of DNA around an octamer of histones proteins.
  Investigating the Drosophila DF31 protein to gain insight into the mechanisms and chromatin maintenance in animal cells
  Dr S Cotterill, Dr A Nohturfft
Applications accepted all year round

Funding Type

PhD Type

The Drosophila DF31 protein is an abundant ribonucleoprotein that localises to euchromatic regions and is involved in maintaining chromosome structure.
  A structural basis for the cross-talk between histones and RNA Polymerase II
  Prof R Stefl, Dr K Kubicek, Prof S Vanacova
Application Deadline: 31 October 2019

Funding Type

PhD Type

Chromatin is a highly flexible architecture in which spatially and temporally coordinated changes between structurally condensed states (transcriptionally repressive), and structurally accessible states (transcriptionally active) regulate gene expression.
  Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
  Prof E D Laue
Applications accepted all year round

Funding Type

PhD Type

The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells.
  Exploring the transcriptomic and chromatin landscapes of fibroblast-like synoviocytes in rheumatoid arthritis
  Dr S Eyre, Mr P Martin, Dr AM Morris
Applications accepted all year round

Funding Type

PhD Type

Genetic studies in rheumatoid arthritis (RA) have been successful in identifying regions of the genome which contribute to disease risk, but it is often unclear which genes they effect.
  Dynamics of the Structure Maintenance of Chromosome (SMC) complexes
  Prof J Palecek
Application Deadline: 31 October 2019

Funding Type

PhD Type

The SMC (Structure Maintenance of Chromosome) complexes are the key components of higher-order chromatin fibers and play important roles in genome stability.
  Molecular analysis of neutrophil extracellular traps (NETs) in rheumatoid arthritis
  Dr HL Wright, Prof RJ Moots
Applications accepted all year round

Funding Type

PhD Type

Neutrophil extracellular traps (NETs) kill pathogens via the release of chromatin and anti-microbial granule enzymes in an extracellular mesh or “net”.
  Role of telomere attrition in cardiometabolic disease risk
  Dr J Buxton, Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

Common conditions such as Type 2 diabetes (T2D) and coronary artery disease (CAD) are complex disorders caused by a myriad of interacting genetic and lifestyle factors.
  Plant responses to stress, metabolites for health and fuel from cell walls.
  Prof A Devoto
Applications accepted all year round

Funding Type

PhD Type

Projects are available in the following areas. Stress responses in crops and sustainable biomass production and processing. The project aims at elucidating several aspects of the control of plant defences and to identify environmentally friendly forms of plant protectants, leading to enhanced crop yields.
  Transcription control and immune evasion in African trypanosomes
  Research Group: Division of Cell & Molecular Biology
  Prof G Rudenko
Applications accepted all year round

Funding Type

PhD Type

Trypanosomes are unicellular eukaryotes which cause African Sleeping Sickness, which is endemic to subSaharan Africa. Trypanosomes can be easily grown as suspension cell lines in the laboratory, where they are straightforward to manipulate and genetically modify.
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