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chromosome PhD Projects, Programs & Scholarships

We have 23 chromosome PhD Projects, Programs & Scholarships

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  Actin-dependent mechanisms of chromosome segregation in mammalian eggs
  Dr B Mogessie
Applications accepted all year round

Funding Type

PhD Type

Every human life starts when an egg is fertilised by a sperm. Fertilisable eggs are produced from oocytes by a specialised form of cell division called meiosis (1).
  Structural and biochemical analysis of chromosome segregation in yeast
  Dr D Barford
Application Deadline: 3 December 2019

Funding Type

PhD Type

Our research is focused on understanding the mechanisms and regulation of chromosome segregation in mitosis. During the cell cycle, accurate chromosome segregation ensures that both daughter cells inherit the correct complement of chromosomes.
  Dynamics of the Structure Maintenance of Chromosome (SMC) complexes
  Prof J Palecek
Application Deadline: 31 October 2019

Funding Type

PhD Type

The SMC (Structure Maintenance of Chromosome) complexes are the key components of higher-order chromatin fibers and play important roles in genome stability.
  Developing methods for the analysis of chromosome conformation data
  Dr T Thorne
Applications accepted all year round

Funding Type

PhD Type

Chromosome conformational data allows us to investigate the three dimensional structure of the genome. This project will involve developing novel computational and statistical methods for the analysis of genomic contact data.
  Engineering synthetic ribosomal RNAs (rRNAs) in yeast
  Prof P Cai, Prof D Delneri
Applications accepted all year round

Funding Type

PhD Type

Advances in DNA synthesis technology have led to rapid growth in the field of synthetic biology, heralding a nascent era of synthetic genomics.
  Structure, function and evolution of plant telomere components
  Prof J Fajkus, Prof J Palecek
Application Deadline: 31 October 2019

Funding Type

PhD Type

Telomeres are terminal, but nevertheless integral parts of chromosomes, and as such they are also formed and function as supramolecular nucleoprotein (chromatin) structures.
  Centromere inheritance in S. pombe and beyond
  Dr L Subramanian
Applications accepted all year round

Funding Type

PhD Type

Accurate chromosome segregation relies on the stable inheritance of functional centromeres through generations. A key determinant of centromere function is the histone H3 variant CENP-A (Centromere Protein A), that epigenetically marks and specifies active centromeres.
  Defining the sequence requirements for neo-centromere function in the fission yeast Schizosaccharomyces pombe
  Dr W R A Brown, Dr W Wickstead
Applications accepted all year round

Funding Type

PhD Type

Centromeres are the regions of the chromosome necessary for accurate segregation at cell division. They bind a complex set of proteins called the kinetochore which in turn tethers the chromosome to the microtubules of the spindle at cell division.
  Investigating the Drosophila DF31 protein to gain insight into the mechanisms and chromatin maintenance in animal cells
  Dr S Cotterill, Dr A Nohturfft
Applications accepted all year round

Funding Type

PhD Type

The Drosophila DF31 protein is an abundant ribonucleoprotein that localises to euchromatic regions and is involved in maintaining chromosome structure.
  Elucidating the mechanism of SMC complexes
  Prof M Dillingham
Applications accepted all year round

Funding Type

PhD Type

The segregation of bacterial chromosomes is orchestrated by the co-ordinated actions of ParB and condensin [1]. ParB (also called Spo0J) is a site-specific DNA binding protein that binds at and around parS sequences near the origin of replication to form “ParB networks” which define the bacterial centromere [2].
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