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chromosome PhD Projects, Programmes & Scholarships
We have 24 chromosome PhD Projects, Programmes & Scholarships
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Chromosome substitution strains from Chinese wild mice
Supervisors. Principal supervisor. Professor/Dr Minyan Wang…. (XJTLU). Co-supervisor. Professor/Dr Jing Zhao……...(JITRI). Read more
3D genome folding and its role in DNA-based processes
The organization of genomic DNA into chromatin fibres and nucleosomes and their regulation by histone modifications is well understood, as is the relevance of these mechanisms for gene regulation. Read more
MSc by Research: Identification of PP2A substrates during oocyte meiosis
Female meiosis is particularly error-prone, leading to chromosomally abnormal embryos that account for >10% of human pregnancies and, for women nearing menopause, the incidence may exceed 50%. Read more
Engineering synthetic ribosomal RNAs (rRNAs) in yeast
Advances in DNA synthesis technology have led to rapid growth in the field of synthetic biology, heralding a nascent era of synthetic genomics. Read more
Functions of the cytoskeleton in mammalian oocyte meiosis
The Max Planck Institute for Multidisciplinary Sciences is a leading international research institute of exceptional scientific breadth. Read more
Gene regulation using a CRISPR/Cas9-based histone variant deposition
Pseudogenes are functionless remnants of DNA that are copied from parental genes during evolution. EP400 N-terminal-Like (EP400NL) gene was thought to be a pseudogene, located next to the parental EP400 gene in the chromosome. Read more
How does paclitaxel kill cells and why do some cells evade it?
Paclitaxel (Taxol) is a microtubule-stabilizing drug widely used for the treatment of breast, ovarian and lung cancers. For many years, it was thought to kill cancer cells by inducing mitotic arrest, thus preventing proliferation. Read more
The role of non-coding RNAs and epitranscriptomics in shaping 3D chromatin architecture in stem cells.
We are looking for an enthusiastic PhD student interested in working on non-coding RNAs and chromatin architecture at the Center for Human Technologies @IIT (Genova-Italy). Read more
Diversifying the histone code: defining the role of non-canonical phosphorylation in chromatin structure
This opportunity will remain open until the position has been filled. Post-translational modifications (PTMs) of histones are known to direct chromatin structure and thus gene transcription. Read more
Regulation of variant antigen gene expression in African trypanosomes
We investigate the molecular biology of African trypanosomes, with a particular focus on the epigenetic control of gene expression. Trypanosomes are… Read more
PhD studentship in Machine learning and Network analysis applied to Single-Cell and Population Genomics
This computational PhD project will leverage single-cell genomics, machine learning and formal network analysis methods to interpret data arising from genome-wide association studies (GWAS). Read more
Isolation and classification of bacteriophages purified from maternal breast milk and determination of their role in bacterial community development. (ref: RDFC22/HLS/APP/DSMITH4)
Survival of very preterm infants has significantly increased over the last 20 years, but late onset sepsis (LOS) and serious bowel disease including necrotising enterocolitis (NEC) remain major causes of death and disability in those born < 32 weeks of gestation). Read more
Characterising the role of temperate bacteriophages in early colonisation of the lung by Pseudomonas aeruginosa and development of chronic bacterial infection. (ref: RDFC22/HLS/APP/DSMITH3)
Chronic respiratory disease including Cystic Fibrosis (CF) and non-cystic fibrosis bronchiectasis have high mortality rates due to the progressive loss… Read more
Longitudinal carriage of temperate phages of Pseudomonas aeruginosa and their role in the chronically infected lung. (ref: RDFC22/HLS/APP/DSMITH2)
Chronic respiratory disease including Cystic Fibrosis (CF) and non-cystic fibrosis bronchiectasis have high mortality rates due to the progressive loss… Read more
Unlocking the potential of a novel microtubule growth inhibitor as a cancer therapeutic
Microtubules are a functionally versatile and critically important component of the cytoskeleton and as a result have been one of the most actively pursued therapeutic targets of the past 60 years. Read more
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