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chromosome PhD Projects, Programmes & Scholarships

We have 24 chromosome PhD Projects, Programmes & Scholarships

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We have 24 chromosome PhD Projects, Programmes & Scholarships

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3D genome folding and its role in DNA-based processes

The organization of genomic DNA into chromatin fibres and nucleosomes and their regulation by histone modifications is well understood, as is the relevance of these mechanisms for gene regulation. Read more

MSc by Research: Identification of PP2A substrates during oocyte meiosis

Female meiosis is particularly error-prone, leading to chromosomally abnormal embryos that account for >10% of human pregnancies and, for women nearing menopause, the incidence may exceed 50%. Read more

Functions of the cytoskeleton in mammalian oocyte meiosis

The Max Planck Institute for Multidisciplinary Sciences is a leading international research institute of exceptional scientific breadth. Read more

Gene regulation using a CRISPR/Cas9-based histone variant deposition

Pseudogenes are functionless remnants of DNA that are copied from parental genes during evolution. EP400 N-terminal-Like (EP400NL) gene was thought to be a pseudogene, located next to the parental EP400 gene in the chromosome. Read more

How does paclitaxel kill cells and why do some cells evade it?

Paclitaxel (Taxol) is a microtubule-stabilizing drug widely used for the treatment of breast, ovarian and lung cancers. For many years, it was thought to kill cancer cells by inducing mitotic arrest, thus preventing proliferation. Read more

Isolation and classification of bacteriophages purified from maternal breast milk and determination of their role in bacterial community development. (ref: RDFC22/HLS/APP/DSMITH4)

Survival of very preterm infants has significantly increased over the last 20 years, but late onset sepsis (LOS) and serious bowel disease including necrotising enterocolitis (NEC) remain major causes of death and disability in those born < 32 weeks of gestation). Read more

Unlocking the potential of a novel microtubule growth inhibitor as a cancer therapeutic

Microtubules are a functionally versatile and critically important component of the cytoskeleton and as a result have been one of the most actively pursued therapeutic targets of the past 60 years. Read more

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