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chromosome segregation PhD Projects, Programs & Scholarships

We have 12 chromosome segregation PhD Projects, Programs & Scholarships

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  Structural and biochemical analysis of chromosome segregation in yeast
  Dr D Barford
Application Deadline: 3 December 2019

Funding Type

PhD Type

Our research is focused on understanding the mechanisms and regulation of chromosome segregation in mitosis. During the cell cycle, accurate chromosome segregation ensures that both daughter cells inherit the correct complement of chromosomes.
  Safe-guarding genome integrity during mammalian cell division
  Dr U Gruneberg
Application Deadline: 10 January 2020

Funding Type

PhD Type

The key goal of cell division is the correct segregation of the genetic material over multiple generations. Failure of this process can result in cell death or trigger tumorigenesis.
  Regulation of mitotic and meiotic chromosome function by different cohesin complexes
  Research Group: Meiosis
  Dr E Martinez-Perez
Application Deadline: 1 December 2019

Funding Type

PhD Type

Cohesin, the complex that provides sister chromatid cohesion (SCC) to ensure correct chromosome segregation during cell division, belongs to a family of SMC (structural maintenance of chromosomes) proteins conserved from bacteria to humans (1).
  Dynamics of the Structure Maintenance of Chromosome (SMC) complexes
  Prof J Palecek
Application Deadline: 31 October 2019

Funding Type

PhD Type

The SMC (Structure Maintenance of Chromosome) complexes are the key components of higher-order chromatin fibers and play important roles in genome stability.
  Molecular mechanisms of eukaryotic SMC complexes
  Research Group: Cell Cycle
  Dr L Aragon
Application Deadline: 1 December 2019

Funding Type

PhD Type

Every cell contains an enormous amount of DNA organised into one or more chromosomes. Chromosomes need to be accessed by components of the cell so that the information they contain can be read and used.
  Investigating the structure and function of the divisome, the multi-protein complex that facilitates cell division in bacteria.
  Dr J Lowe
Application Deadline: 3 December 2019

Funding Type

PhD Type

When bacteria and archaea divide, most form a ring structure that facilitates the separation of mother and daughter cells. The best-known component of the cytokinetic ring is FtsZ, the bacterial tubulin homologue.
  Establishment of Sister Chromatid Cohesion during DNA Replication
  Dr F Uhlmann, Dr J Diffley
Application Deadline: 12 November 2019

Funding Type

PhD Type

A joint Cric funded PhD position for the 2020 programme between the labs of Dr Frank Uhlmann & John Diffley. Following DNA replication in S phase, the two replication products are held together by the chromosomal cohesin complex.
  Unravelling real-time cytoskeleton dynamics using single molecule imaging tools
  Dr M Molodtsov, Dr S Cox
Application Deadline: 12 November 2019

Funding Type

PhD Type

A joint Crick-King’s College London funded PhD position for the 2020 programme between the labs of Maxim Molodtsov and Susan Cox.
  Probing a DNA segregation machine at single molecule level to combat antibiotic resistance
  Dr D Barilla, Prof M Leake
Application Deadline: 5 January 2020

Funding Type

PhD Type

Bacterial multidrug resistance is a global burden on human health worldwide. Large, low copy number plasmids responsible for antibiotic resistance have.
  Caught in a Venus flytrap: investigating the segregation dynamics of a multidrug resistance plasmid
  Dr D Barilla, Dr M Hawkins
Application Deadline: 30 June 2020

Funding Type

PhD Type

Bacterial multidrug resistance is a growing burden on human health worldwide. Large, low copy number plasmids carrying resistance genes shuttle easily from cell to cell in bacterial populations, causing intra-species and inter-species spreading of antibiotic resistance.
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