FREE PhD study and funding virtual fair REGISTER NOW FREE PhD study and funding virtual fair REGISTER NOW

chromosome segregation PhD Projects, Programmes & Scholarships

We have 9 chromosome segregation PhD Projects, Programmes & Scholarships

Discipline

Discipline

All disciplines

Location

Location

All locations

Institution

Institution

All Institutions

PhD Type

PhD Type

All PhD Types

Funding

Funding

All Funding


We have 9 chromosome segregation PhD Projects, Programmes & Scholarships

PhD saved successfully

Identification and functional analysis of novel factors driving meiotic chromosome segregation in Caenorhabditis elegans

We are interested in identifying new factors involved in promoting faithful chromosome segregation during meiosis. From previous mass spectrometry-based screenings we have isolated several uncharacterized proteins that seem to hold important roles in crossover formation and DNA repair. Read more

MSc by Research: Identification of PP2A substrates during oocyte meiosis

Female meiosis is particularly error-prone, leading to chromosomally abnormal embryos that account for >10% of human pregnancies and, for women nearing menopause, the incidence may exceed 50%. Read more

Homologous recombination at human centromeres – friend or foe?

The centromere is a region of chromatin that serves as a platform for the kinetochore machinery assembly, hence is essential for accurate chromosome segregation during cell division. Read more

How does paclitaxel kill cells and why do some cells evade it?

Paclitaxel (Taxol) is a microtubule-stabilizing drug widely used for the treatment of breast, ovarian and lung cancers. For many years, it was thought to kill cancer cells by inducing mitotic arrest, thus preventing proliferation. Read more

3D genome folding and its role in DNA-based processes

The organization of genomic DNA into chromatin fibres and nucleosomes and their regulation by histone modifications is well understood, as is the relevance of these mechanisms for gene regulation. Read more

How does the TRAIP ubiquitin ligase guard the mammalian genome from damage?

The TRAIP ubiquitin ligase is a key regulator of genome integrity in mammalian cells. The importance of TRAIP is highlighted by the fact that mutation leads to a human disease syndrome, whilst over-expression of TRAIP can be associated with human cancer. Read more

Unlocking the potential of a novel microtubule growth inhibitor as a cancer therapeutic

Microtubules are a functionally versatile and critically important component of the cytoskeleton and as a result have been one of the most actively pursued therapeutic targets of the past 60 years. Read more

Understanding gene regulation by HDAC1 complexes in development and cancer

Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more
  • 1

Filtering Results