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chromosome segregation PhD Projects, Programs & Scholarships

We have 5 chromosome segregation PhD Projects, Programs & Scholarships

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  Actin-dependent mechanisms of chromosome segregation in mammalian eggs
  Dr B Mogessie
Applications accepted all year round
Every human life starts when an egg is fertilised by a sperm. Fertilisable eggs are produced from oocytes by a specialised form of cell division called meiosis (1).
  Chromosome Segregation in the Mammalian Germline
  Research Group: MRC Human Genetics Unit
  Dr I Adams
Application Deadline: 19 April 2019
This is one of several projects available on an MRC funded 4-year multi-disciplinary PhD programme in Human Genetics, Genomics and Disease at the MRC Human Genetics Unit (HGU), part of the Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh.
  Centromere inheritance in S. pombe and beyond
  Dr L Subramanian
Applications accepted all year round
Accurate chromosome segregation relies on the stable inheritance of functional centromeres through generations. A key determinant of centromere function is the histone H3 variant CENP-A (Centromere Protein A), that epigenetically marks and specifies active centromeres.
  Defining the sequence requirements for neo-centromere function in the fission yeast Schizosaccharomyces pombe
  Dr W R A Brown, Dr W Wickstead
Applications accepted all year round
Centromeres are the regions of the chromosome necessary for accurate segregation at cell division. They bind a complex set of proteins called the kinetochore which in turn tethers the chromosome to the microtubules of the spindle at cell division.
  Elucidating the mechanism of SMC complexes
  Prof M Dillingham
Applications accepted all year round
The segregation of bacterial chromosomes is orchestrated by the co-ordinated actions of ParB and condensin [1]. ParB (also called Spo0J) is a site-specific DNA binding protein that binds at and around parS sequences near the origin of replication to form “ParB networks” which define the bacterial centromere [2].
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