Mapping the circadian clock-dependent regulation of the secretory pathway
Prof K E Kadler, Dr Q-J Meng
Applications accepted all year round
The protein secretory pathway in cells comprises a series of membranous compartments and transport vesicles that the cell uses to synthesise, post-translationally modify, and move proteins for delivery to the plasma membrane or for secretion to the extracellular matrix.
(BBSRC DTP CASE) Applying – omics methods to map the circadian matrisome
Dr J Swift, Dr Q-J Meng, Prof K E Kadler
31 January 2019
Circadian rhythm regulates and synchronises biological processes through a daily cycle. Molecular clocks in cells throughout the human body are entrained to a ‘master clock’ located in the hypothalamus, and cells in almost all tissues have been found to contain rhythmic genes.