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clinical development PhD Projects, Programs & Scholarships

We have 317 clinical development PhD Projects, Programs & Scholarships

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Showing 1 to 10 of 317
  Pre-clinical testing of new therapeutic treatments for cystic kidney disease
University of Leeds Faculty of Medicine and Health
  Dr S Bell, Prof C A Johnson
Applications accepted all year round
The primary cilium on the ventral surface of most vertebrate cells acts as an “antennae” that receives and transduces chemo- and mechanosensory signals.
Details
Type/Funding
  Personalised surgery for colorectal cancer cure by use of fluorescence guidance- increasing safety & cancer precision
University College Dublin School of Medicine
  Dr R Cahill
Applications accepted all year round
Surgery is the best treatment for colorectal cancer, most especially for cure. It remains a major operation with considerable risks meaning that every effort should be made to ensure maximum safety and effectiveness in obtaining a complete resection.
Details
Type/Funding
  Use of electronic health records for efficient evaluation of biomarkers as diagnostic tools and surrogate endpoints in Alzheimer’s disease
University of Leicester Department of Health Sciences
  Dr R Owen, Dr S Bujkiewicz, Dr T Quinn
Application Deadline: 3 April 2019
Dementia is recognised as one of the greatest public health threats of our time, both in the UK and globally. Alzheimer’s disease is the most common cause of dementia, but drug development has recently failed [1].
Details
Type/Funding
  Non-invasive Mapping of Oxygen Extraction Fraction in Patients with Breast Cancer: Development of Novel Multi-Parametric Relaxometry Magnetic Resonance Imaging (MRI) Methods
Aberdeen University School of Medicine, Medical Sciences & Nutrition
  Dr J He, Dr Y Masannat, Prof D Lurie
Application Deadline: 29 March 2019
This project aims to translate, optimise and extend quantitative oxygen extraction fraction mapping based on oxygen enriched air inspiration and magnetic resonance (MR) relaxometric imaging for human application.
Details
Type/Funding
  Cutting off the fuel supply to starve cancer: Identifying metabolic vulnerabilities in cancer
Peter MacCallum Cancer Centre Sir Peter MacCallum Department of Oncology, University of Melbourne
  Dr K Brown, Dr A. Cox
Applications accepted all year round
A universal characteristic of all cancer cells is the reprogramming of cell metabolism to provide the energy and building blocks necessary to support proliferation and survival.
Details
Type/Funding
  Targeting steroid metabolism to block colorectal cancer proliferation
University of Birmingham Institute of Metabolism and Systems Research
  Dr P Foster, Dr L Cox
Applications accepted all year round
Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds.
Details
Type/Funding
  The search for valid surrogate outcomes: review of current evidence and development of practical strategies for surrogate evaluation
University of Edinburgh College of Medicine and Veterinary Medicine
  Dr C Weir, Prof S Lewis
Application Deadline: 5 April 2019
Background. In clinical trials, a surrogate outcome is one which is used in place of the true clinical outcome of interest.
Details
Type/Funding
  Elucidating the protein interaction network of serum- and glucocorticoid-regulated kinase 1 (SGK1)
Peter MacCallum Cancer Centre Sir Peter MacCallum Department of Oncology, University of Melbourne
  Dr K Brown
Applications accepted all year round
The phosphoinositide 3-kinase (PI3K) pathway is a master regulator of numerous cellular phenotypes associated with cancer including cell survival, proliferation, growth, altered metabolism and malignant transformation.
Details
Type/Funding
  Metabolic reprogramming and chemotherapy resistance in triple-negative breast cancer
Peter MacCallum Cancer Centre Sir Peter MacCallum Department of Oncology, University of Melbourne
  Dr K Brown
Applications accepted all year round
Treatment options for the triple-negative breast cancer (TNBC) subtype of breast cancer are limited to conventional chemotherapy agents.
Details
Type/Funding
  Development of the hematopoietic/ immune system in the embryo: obtaining a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development
University of Oxford Radcliffe Department of Medicine
  Prof M DeBruijn
Application Deadline: 26 July 2019
Development of the hematopoietic/ immune system in the embryo. Our aim is to obtain a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development and determine the contribution of these cells to the emerging hematopoietic and immune systems of the embryo.
Details
Type/Funding
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