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clinical genetics PhD Projects, Programs & Scholarships

We have 117 clinical genetics PhD Projects, Programs & Scholarships

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  Improved classification of myositis disease subtypes using statistical genetics approaches for stratified medicine
  Dr J Lamb, Dr AM Morris, Dr H Chinoy
Applications accepted all year round

Funding Type

PhD Type

Keywords. idiopathic inflammatory myopathy, myositis, genetics, disease classification, stratified medicine. Idiopathic inflammatory myopathies (IIM) are heterogeneous autoimmune diseases characterized by inflammation of skeletal muscle (myositis).
  Machine learning approaches for the clinical diagnosis of autoimmune disease
  Dr A Auer-Fowler, Dr P Green
Application Deadline: 12 April 2020

Funding Type

PhD Type

Autoimmune diseases have a range of complex symptoms and are therefore typically hard to diagnose. Current diagnostic methods are often invasive, painful, and subjective.
  Pharmacometrics modelling-based dose-finding and synthetic control arms established using longitudinal analyses to improve efficiency in oncology clinical drug development.
  Prof M Chappell
Application Deadline: 30 June 2020

Funding Type

PhD Type

Advancements in the field of oncology are rapidly changing the life expectancy of patients across many cancers.
  Transferability of genetic risk scores for complex human diseases across diverse population groups
  Dr AM Morris, Dr J Bowes
Applications accepted all year round

Funding Type

PhD Type

Genome-wide association studies (GWAS) have been extremely successful in identifying DNA variants that are associated with a wide range of complex human traits and common diseases.
  Understanding disease mechanisms in autoimmune inflammatory muscle disease
  Dr J Lamb, Dr H Chinoy
Applications accepted all year round

Funding Type

PhD Type

The idiopathic inflammatory myopathies are a spectrum of rare autoimmune disorders characterized by inflammation of muscle tissue (myositis), which leads to muscle weakness and fatigue, and heterogeneous systemic organ involvement.
  Developing and applying computational methods to understand the genetics of ageing
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Ageing is the chief biomedical challenge of the 21st century, yet it remains a major puzzle of biology. Although it is clear that the process of ageing has a strong genetic component, much work remains to elucidate how the genome regulates ageing.
  Genetics of inherited cardiovascular disease: Using molecular genetic analysis of cardiovascular disease as a tool to define disease mechanisms and therapeutic targets.
  Prof H Watkins, Prof H Ashrafian, Prof C Redwood, Prof M Farrall
Application Deadline: 24 July 2020

Funding Type

PhD Type

I have had a longstanding focus on inherited heart muscle diseases, in particular hypertrophic cardiomyopathy, which is a relatively common Mendelian condition which puts affected individuals at risk of sudden cardiac death.
  Precision genetics to improve Asthma prediction, diagnosis and treatment in children
  Dr J O'Sullivan, Dr T Fadason
Application Deadline: 15 April 2020

Funding Type

PhD Type

Asthma is a prevalent respiratory condition in children and adults globally, with the prevalence in NZ among the highest in the developed world.
  Using computational biology to understand how cancer-associated mutations disrupt protein complexes
  Research Group: MRC Human Genetics Unit
  Dr J Marsh
Application Deadline: 3 April 2020

Funding Type

PhD Type

Applications are invited from outstanding candidates to join the MRC Human Genetics Unit (HGU), part of the Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh.
  An investigation of psychological and clinical factors associated with the development of chronic or persistent pain in children and young people with inflammatory and non-inflammatory musculoskeletal conditions.
  Dr L Cordingley, Prof W Thomson, Dr R Lee, Dr J McDonagh
Applications accepted all year round

Funding Type

PhD Type

Background. Juvenile Idiopathic Arthritis (JIA) is an inflammatory arthritis presenting in children and young people. Pain is one of the main features of JIA and it is often described as one of the most burdensome yet invisible symptoms of this long-term condition.
  Functional coronary artery disease genetics - Defining the function of new causal atherosclerosis genes from CAD GWAS loci using in vitro and in vivo models
  Dr G Douglas, Prof K Channon
Application Deadline: 24 July 2020

Funding Type

PhD Type

Despite significant advancements in its treatment coronary artery disease is the leading cause of death in both the UK and world wide, accounting for over 66,000 deaths in the UK each year.
  Laboratory of Gene Regulation
  Prof D Higgs, Prof J Hughes, Dr R Gibbons, Dr V Buckle
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation.
  Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
  Prof Claus Nerlov, Prof P Vyas
Application Deadline: 24 July 2020

Funding Type

PhD Type

The focus of the Nerlov laboratory is to use single cell genomics and functional analysis, combined with advanced mouse genetics, to study the function of hematopoietic stem– and progenitor cells in normal development and during ageing.
  Laboratory of Gene Regulation
  Prof D Higgs, Prof J Hughes, Dr R Gibbons, Dr V Buckle
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation.
  Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
  Prof Claus Nerlov, Prof P Vyas
Application Deadline: 24 July 2020

Funding Type

PhD Type

The focus of the Nerlov laboratory is to use single cell genomics and functional analysis, combined with advanced mouse genetics, to study the function of hematopoietic stem– and progenitor cells in normal development and during ageing.
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