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clinical trials PhD Projects, Programs & Scholarships

We have 126 clinical trials PhD Projects, Programs & Scholarships

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  Statistical Modelling of Time Series Data in Severe Asthma Clinical Trials – Enabling Precision Medicine
  Prof S Siddiqui
Application Deadline: 28 September 2020

Funding Type

PhD Type

This studentship is funded by the College of Life Sciences and is placed within the supportive and nurturing environment provided by the Department of Respiratory Sciences, the Leicester Biomedical Research Centre and the Leicester Precision Medicine Institute.
  A multiple modality approach for targeting treatment-resistant ovarian cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer (OvCa) deaths and its five-year survival rate is 43%.
  Inhibition of PRMT5 as a cancer therapy
  Dr K. Sheppard
Applications accepted all year round

Funding Type

PhD Type

Targeted therapy has had profound impact on outcomes for cancer patients.
  Targeting ageing: Genes and compounds with pro-longevity, health-preserving effects
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Ageing is arguably the major biomedical challenge of the 21st century. In model organisms, the process of ageing can be manipulated by both genetic manipulations and dietary interventions.
  Development of antiviral peptidomimetic enzyme inhibitors
  Dr L Trembleau, Dr H Deng
Applications accepted all year round

Funding Type

PhD Type

Coronaviruses are a large group of viruses that circulate and evolve among various animals. They can cause mild human illnesses such as the common cold or more serious respiratory diseases as seen in the recent outbreaks of SARS (2002), MERS (2012), and COVID-19 (2019).
  A key role for FKBPL in the regulation of cancer stem cell signalling and the microenvironment; therapeutic implications for tumour growth and metastasis
  Prof T Robson, Prof D O'Connor
Applications accepted all year round

Funding Type

PhD Type

Cancer stem cells (CSCs) are a special type of cell found within tumours that are able to undergo unlimited self-renewal and are highly resistant to therapy.
  Clinical cancer bioinformatics: developing new bioinformatics methods for improved analysis of cancer gene hybridisation capture panels
  Prof A Papenfuss
Applications accepted all year round

Funding Type

PhD Type

Bioinformatics is the application of mathematics, statistics and computational methods to the analysis of molecular biology data.
  Dynamic prediction modelling in Parkinson’s disease
  Dr D McLernon, Dr A Macleod, Dr C Counsell
Application Deadline: 26 June 2020

Funding Type

PhD Type

1. Background to the project. Parkinson’s disease (PD) is a progressive, disabling, neurodegenerative disorder which is common in the elderly.
  Basic and clinical studies on spinal cord injury
  Dr G Shea
Applications accepted all year round

Funding Type

PhD Type

Spinal cord injury has a devastating effect on affected individuals, who are often of working age and subject to a lifetime of dependency and debilitation.
  Analytic methods for detecting and making sense of somatic genomic rearrangements
  Prof A Papenfuss
Applications accepted all year round

Funding Type

PhD Type

Bioinformatics is the application of mathematics, statistics and computational methods to the analysis of molecular biology data.
  Fueling chemotherapy resistance in triple-negative breast cancer
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

Triple-negative breast cancer (TNBC) is a molecularly heterogeneous group of diseases defined by the lack of estrogen receptor (ER), progesterone receptor (PR) and absence of human epidermal growth factor receptor-2 (HER2) amplification.
  Genomic determinants of long-term survival in ovarian cancer
  Research Group: Cancer Genetics & Genomics Laboratory
  Prof D. Bowtell, Dr D Garsed
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer is an aggressive disease in which only ~30% of women survive 5 years or more. Despite a poor prognosis, a subset of patients are highly responsive to chemotherapy, and some become long-term survivors (>10 years survival).
  Investigating the requirements of pro-inflammatory signaling in skin and head & neck Squamous Cell Carcinomas
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Squamous cell carcinomas (SCC) are amongst the most common cancer types afflicting man. SCCs most frequently arise from stratified squamous epithelia such as the epidermis or the mucosae of the head and neck.
  mRNA translation reprogramming and metabolic re-wiring in response to ribosome-targeted therapies
  Prof R. Pearson, Dr J Kang
Applications accepted all year round

Funding Type

PhD Type

Increased synthesis and activity of ribosomes are associated with oncogenesis downstream of the major oncogenes including MYC, RAS and PI3K.
  Understanding the mechanisms of neuroendocrine tumour response to radionuclide therapy
  Prof R Hicks, Assoc Prof C Cullinane
Applications accepted all year round

Funding Type

PhD Type

Neuroendocrine tumours (NET) represent a heterogeneous group of tumours that arise in specialized cells found throughout the body.
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