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colorectal PhD Projects, Programs & Scholarships

We have 12 colorectal PhD Projects, Programs & Scholarships

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  The Gut Microbiota and Colorectal Surgery
  Dr M Lewis, Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

"Background. Antibiotic use prior to and following colorectal surgery is conventional practice, and is aimed at reducing the incidence of postoperative infection which is a major risk of such surgery.
  Targeting steroid metabolism to block colorectal cancer proliferation
  Dr P Foster, Dr L Cox
Applications accepted all year round

Funding Type

PhD Type

Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds.
  Modelling the effects on tumour phenotype and mutational landscape of common genetic variance linked with colorectal cancer susceptibility
  Research Group: MRC Human Genetics Unit
  Prof M Dunlop, Dr R Jackstadt
Application Deadline: 30 September 2019

Funding Type

PhD Type

This PhD studentship funded by CRUK and is available to start in November 2019 at the MRC Human Genetics Unit, which is part of the Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh.
  Personalised surgery for colorectal cancer cure by use of fluorescence guidance- increasing safety & cancer precision
  Dr R Cahill
Applications accepted all year round

Funding Type

PhD Type

Surgery is the best treatment for colorectal cancer, most especially for cure. It remains a major operation with considerable risks meaning that every effort should be made to ensure maximum safety and effectiveness in obtaining a complete resection.
  Activity based proteomic probes for profiling CYP2W1 in cancer tissues
  Research Group: Institute of Cancer Therapeutics
  Dr C Sutton, Dr K Pors
Applications accepted all year round

Funding Type

PhD Type

Cytochromes P450 (CYPs) are a superfamily of mixed function oxidases of which CYP1-4 subfamily members are unique in their ability to oxidise drugs.
  The relationship between dietary iron and zinc, and the gut microbiota: Can dietary iron and zinc regime be exploited to improve health?
  Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

"The gut microbiota (100 trillion cells) outnumber human cells by 10 to 1. Its composition of around 500 to 1000 species is specific for each individual and is dynamic, changing with age, health and diet.
  Inhibition of PRMT5 as a cancer therapy
  Dr K. Sheppard
Applications accepted all year round

Funding Type

PhD Type

Targeted therapy has had profound impact on outcomes for cancer patients.
  Overcoming therapy induced reprogramming of metabolism in melanoma
  Dr K. Sheppard, Dr L Smith
Applications accepted all year round

Funding Type

PhD Type

Therapies that target oncogenes in cancer have revolutionised cancer care. The major benefits of targeted therapies are high response rates and manageable toxicities, however they do not result in cures in the vast majority of patients.
  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Applications accepted all year round

Funding Type

PhD Type

Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
  Dynamic interplay of cell shape and tumour evolution
  Dr F Spill, Prof I Tomlinson
Applications accepted all year round

Funding Type

PhD Type

Tumour cells are long known to appear in vastly diverse shapes, both across patients and within a single tumour. This is in stark contrast to the regularity of cell shapes of healthy epithelial tissues from which most tumours originate.
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