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We have 20 colorectal cancer PhD Projects, Programmes & Scholarships
colorectal cancer PhD Projects, Programmes & Scholarships
We have 20 colorectal cancer PhD Projects, Programmes & Scholarships
Targeting steroid metabolism to block colorectal cancer proliferation
Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds. Read more
(MB-PhD) Smaller, Better, Faster, Stronger: real-time colorectal cancer management using nanopore sequencing.
Colorectal cancer (CRC) is ranking among the leading causes of cancer-related morbidity and mortality and where early onset is increasing. Read more
Quantum imaging of bioelectric signalling in colorectal cancer organoids
This project is part of the EPSRC Centre for Doctoral Training in Quantum Technology Engineering at the University of Southampton https://qte.ac.uk/). Read more
PhD Opportunity - Mechanisms of metastasis: Defining how the sialomucin Podocalyxin drives metastatic colorectal cancer
'TO APPLY, PLEASE CLICK INSTITUTION WEBSITE'. Summary. The majority of cancer-related deaths are associated with metastasis from the primary tumour. Read more
PhD Opportunity - Investigating the Colonic Microbiome – Immune Interactions to Prevent Colorectal Cancer
'TO APPLY, PLEASE CLICK INSTITUTION WEBSITE'. Project description. Around 40% of individuals undergoing bowel screening colonoscopy have pre-malignant colorectal adenomas. Read more
A new level of gene regulation in tumour heterogeneity in colorectal cancer organoid models
Application deadline - midday (GMT) Friday 10 January 2025. Additional supervisor. Professor Dov Stekel, University of Nottingham. Read more
Identifying how mucinous tumours use glycobiology to resist chemotherapy
Mucinous colorectal cancers are easily identifiable early in a patient’s care due to their extracellular glycan (sugar)-dominated mucus, which accounts for more than 50% of tumour volume. Read more
Inhibition WNT signalling in colorectal cancer via targeted degradation of FAM83F-CK1a and FAM83G-CK1a complexes
Hyperactivation of WNT/β-catenin signalling is a prominent hallmark of colorectal cancer (CRC). Despite progress in understanding the pathogensis of CRCs, there are still limited treatment options. Read more
Modelling the dynamics of T-cell evolution in cancer
The adaptive immune system, especially T cells, plays a central role in cancer evolution. Reawakening the immune system with immunotherapy can be remarkably effective at treating cancer. Read more
Precision Medicine DTP - The role of common cis-regulatory variation in modifying the penetrance of Lynch Syndrome variants
Research Group:
The Roslin Institute
Background: . Lynch syndrome is caused by loss of function mutations in the mismatch repair (MMR) mechanism that leads to a substantial increase in the mutation rate during cell division. Read more
A Robotic Exoskeletal Sleeve for Flexible Endoscopic Surgery
Colorectal cancer is the second most deadly cancer (0.94 million deaths, 9.4% of all cancer deaths) in 2020 worldwide. Endoscopic Submucosal Dissection (ESD) is a procedure to remove large colorectal cancer tumors by inserting flexible tools into the colon through the anus, without making incisions on the body. Read more
Bowel cancer caused by bacteria
The gut microbiome has a profound effect on health and disease of humans and colorectal cancer (CRC) is one such disease influenced by microorganisms. Read more
Last chance to apply
Black Leaders in Cancer PhD programme: Targeting Siglec immune checkpoints in immunotherapy resistant liver cancer
Hepatocellular carcinoma (HCC) accounts for ~90% of primary liver cancers and has a 5-year survival rate of less than 20%. In 2020, the IMBrave150 trial led to combination immunotherapy becoming first line for advanced HCC. Read more
Bioinspired Nanomaterials Based Miniaturised Soft Robots for High Precision Regiospecific Drug Delivery to Malignant Tumours
Cancer is one of the top global public health challenges, estimated to have caused 10M deaths (2020) according to WHO. Throughout the years, standardised therapeutic protocols have been developed and evolved for the treatment of various types of cancers. Read more
Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives
Research Group:
Institute of Cancer Therapeutics
Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more
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