Summary. The blood-based coagulation and immune complement systems are activated in response to infection or injury. These systems are generally viewed as distinct, but several protein interactions between these systems affect their function and may contribute to disease. Read more
The complement system is a key component of the immune response. Maintaining a balance between activation and inhibition of the complement system is key to preserving tissue homeostasis and enabling immune surveillance. Read more
Commercial partner: DJS Antibodies. Understanding the nature of antibody-antigen interactions and how these relate to functional outcomes is vital in guiding the rational design of next-generation vaccines and monoclonal antibody (mAb) therapeutics. Read more
This project is one of a number that are in competition for funding from the GW4 BioMed2 MRC Doctoral Training Partnership which is offering up to 20 studentships for entry in September 2024. Read more
Dysregulation of innate immunity has been implicated as playing a key role in the development of age-related macular degeneration (AMD) – a major form of blindness in the industrialised world (see [1-5]). Read more
Medical devices and surgical innovation have been under-researched in the past, leading to safety concerns and numerous high-profile scandals, such as those related to metal-on-metal hip replacements and surgical mesh. Read more
Project. Messenger RNA (mRNA) provides a highly flexible platform for the development of vaccines. A robust immune response typically requires both an antibody response and a T-cell response. Read more
Application Deadline. Wednesday 8 November 2023, 13:00 (GMT). King's College London are seeking students of academic excellence to join our Health Faculties. Read more
As part of the Interdisciplinary Circular Economy Centre for Mineral-Based Construction Materials (ICEC-MCM), we have a PhD scholarship to investigate technical aspects of circular economy applied to construction materials. Read more
Medical image analysis using Deep Learning models involves training on progressively larger datasets. Homogeneity of data within the training set, particularly in its representation of diverse population sub-groups and various disease stages, substantially influences model effectiveness. Read more
Our research is focused on understanding the mechanisms and regulation of chromosome segregation in mitosis. During the cell cycle, accurate chromosome segregation ensures that both daughter cells inherit the correct complement of chromosomes. Read more
Mixed reality (MR) embeds virtual content in the real world. Many believe MR is the next big ubiquitous computing paradigm that will replace the smartphone – and big tech companies are investing heavily in the development of MR-based headsets. Read more
Knowledge synthesis can be a slow and cumbersome process but is an essential tool for medical and public health policy-makers. Formal systematic reviews require rigid protocols and extensive human effort from trained professionals, whereas a massive volume of research evidence emerges every year. Read more
Our aim is to develop novel Positron Emission Tomography (PET) radiotracers for imaging the brain. PET is a non-invasive molecular imaging technique which enables visualization and quantification of various biological targets in vivo (e.g., receptor, enzyme). Read more
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