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We have 44 complement PhD Projects, Programmes & Scholarships

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complement PhD Projects, Programmes & Scholarships

We have 44 complement PhD Projects, Programmes & Scholarships

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Unravelling the molecular link between coagulation and immunity

Summary. The blood-based coagulation and immune complement systems are activated in response to infection or injury. These systems are generally viewed as distinct, but several protein interactions between these systems affect their function and may contribute to disease. Read more

High-throughput characterisation of the functional antibody epitope landscape of surface protein targets to guide vaccine and biologic design

Commercial partner: DJS Antibodies. Understanding the nature of antibody-antigen interactions and how these relate to functional outcomes is vital in guiding the rational design of next-generation vaccines and monoclonal antibody (mAb) therapeutics. Read more

Insights into eye disease: understanding the molecular basis of age-related macular degeneration

Dysregulation of innate immunity has been implicated as playing a key role in the development of age-related macular degeneration (AMD) – a major form of blindness in the industrialised world (see [1-5]). Read more

Development of integrated microfluidic chips for making mRNA nanomedicines

Project. Messenger RNA (mRNA) provides a highly flexible platform for the development of vaccines. A robust immune response typically requires both an antibody response and a T-cell response. Read more

Circular Economy of Mineral-Based Construction Materials

  Research Group: School of Civil Engineering
As part of the Interdisciplinary Circular Economy Centre for Mineral-Based Construction Materials (ICEC-MCM), we have a PhD scholarship to investigate technical aspects of circular economy applied to construction materials. Read more

Exploration of deep learning based generative adversarial networks (GANs) to mitigate bias in the evaluation of medical images among diverse population and disease sub-groups

Medical image analysis using Deep Learning models involves training on progressively larger datasets. Homogeneity of data within the training set, particularly in its representation of diverse population sub-groups and various disease stages, substantially influences model effectiveness. Read more

Cryo-EM study of the human kinetochore

Our research is focused on understanding the mechanisms and regulation of chromosome segregation in mitosis. During the cell cycle, accurate chromosome segregation ensures that both daughter cells inherit the correct complement of chromosomes. Read more

Adaptive Interaction Techniques in Mixed Reality

Mixed reality (MR) embeds virtual content in the real world. Many believe MR is the next big ubiquitous computing paradigm that will replace the smartphone – and big tech companies are investing heavily in the development of MR-based headsets. Read more

Automating knowledge synthesis in biomedical literature using AI and language models

Knowledge synthesis can be a slow and cumbersome process but is an essential tool for medical and public health policy-makers. Formal systematic reviews require rigid protocols and extensive human effort from trained professionals, whereas a massive volume of research evidence emerges every year. Read more

Development of PET Radiotracers of AMPA

Our aim is to develop novel Positron Emission Tomography (PET) radiotracers for imaging the brain. PET is a non-invasive molecular imaging technique which enables visualization and quantification of various biological targets in vivo (e.g., receptor, enzyme). Read more

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