EPSRC & BBSRC Centre for Doctoral Training in Synthetic Biology
The EPSRC & BBSRC Centre for Doctoral Training in Synthetic Biology (SynBioCDT) combines the fundamental understanding of biological systems with the principles of engineering, so as to create the next generation of industrial and academic leaders in Synthetic Biology.
Deciphering the regulation of non-coding RNAs in a hypoxic tumour microenvironment
Prof F Buffa, Prof A Harris
11 January 2019
The role of the microenvironment in driving tumour progression is increasingly recognized. Hypoxia is one of the key microenvironmental changes between tumour and normal tissue, and adaptation of cancer cells to this hostile environment contributes to their malignancy and aggressive phenotype (1).