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cystic fibrosis PhD Projects, Programs & Scholarships

We have 18 cystic fibrosis PhD Projects, Programs & Scholarships

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  Expression and purification of the cystic fibrosis transmembrane conductance regulator and development of a high throughput screen for drug discovery
University of Manchester Faculty of Biology, Medicine and Health
  Prof R Ford
Applications accepted all year round
The cystic fibrosis transmembrane conductance regulator protein (CFTR) is a chloride channel than plays an important role in epithelial cells.
Details
Type/Funding
  Using AI to Drive Drug Discovery for Membrane Protein Targets
University of Oxford Department of Biochemistry
  Dr PC Biggin
Application Deadline: 11 January 2019
Lead supervisor. Prof Phil Biggin, Department of Biochemistry, Oxford. Commercial partner. Vertex Pharmaceuticals, Milton site, Oxfordshire.
Details
Type/Funding
  Fabrication of novel hybrid nano-carriers for pulmonary drug delivery
University of Reading School of Pharmacy
  Dr H Al-Obaidi
Applications accepted all year round
Pulmonary drug delivery is a non-invasive route for drug delivery where the lungs provide a thin, yet extremely efficient absorptive mucosal membrane with a good blood supply.
Details
Type/Funding
  Discovering new drugs for Mycobacterium abscessus infections in children
Aston University School of Life & Health Sciences
  Dr J Cox
Application Deadline: 27 January 2019
Applications are invited from candidates to undertake a PhD in the field of microbiology.
Details
Type/Funding
  MRC DiMeN Doctoral Training Partnership: Investigating copper storage in Pseudomonas aeruginosa and its role in pathogenicity
Newcastle University MRC DiMeN Doctoral Training Partnership
  Prof C Dennison, Dr A De Soyza, Prof C Winstanley
Application Deadline: 21 January 2019
Background. This interdisciplinary project bridges world-leading labs with expertise in bacterial cell biology and infection. Novel therapies are needed to overcome increasing antibacterial resistance.
Details
Type/Funding
  Characterising temperate bacteriophages in complex microbial communities and their role in antimicrobial resistance (Ref:SF18/APP/Smith)
Northumbria University Faculty of Health and Life Sciences
  Dr D Smith
Applications accepted all year round
Temperate bacteriophages have the ability to integrate into the chromosome of their target bacterium that leads to a change in the physiology of their bacterial host.
Details
Type/Funding
  Experimental evolution of Pseudomonas aeruginosa in media replicating the conditions of the upper and lower airways
University of Liverpool Institute of Infection and Global Health
  Dr D Neill, Dr J Fothergill
Application Deadline: 20 January 2019
Pseudomonas aeruginosa (Pa) is an important bacterial pathogen in people with cystic fibrosis and other chronic lung conditions. During early infection, Pa adapts to the environment of the respiratory tract, leading to long-lasting, difficult to treat infections.
Details
Type/Funding
  Pyocins as alternatives to antibiotics against Pseudomonas aeruginosa infections
University of Nottingham School of Life Sciences
  Dr C Penfold
Applications accepted all year round
Pyocins are bacteriocins produced by Pseudomonas aeruginosa to kill closely related strains of the same species during times of environmental stress.
Details
Type/Funding
  The interaction of bacterial biofilms with immune cells.
University of Nottingham School of Life Sciences
  Dr L Martinez-Pomares
Applications accepted all year round
Second Supervisor. Miguel Camara/Paul Williams. Project Overview. P. aeruginosa (PA) is emerging as major opportunistic pathogen of clinical relevance.
Details
Type/Funding
  To experimentally determine the environmental influences acting on P. aeruginosa virulence factor expression in biofilms and understand the catalytic mechanism of one of them (the surface tethered aminopeptidase AaaA)
University of Nottingham School of Life Sciences
  Dr K Hardie
Applications accepted all year round
Pseudomonas aeruginosa is an important opportunistic pathogen. It is a problem for the immunocompromised and has attained superbug notoriety since it is evident in hospitals and has inherent resistance to antibiotics.
Details
Type/Funding
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