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cystic fibrosis PhD Projects, Programs & Scholarships

We have 18 cystic fibrosis PhD Projects, Programs & Scholarships

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  Expression and purification of the cystic fibrosis transmembrane conductance regulator and development of a high throughput screen for drug discovery
  Prof R Ford
Applications accepted all year round
The cystic fibrosis transmembrane conductance regulator protein (CFTR) is a chloride channel than plays an important role in epithelial cells.
  Using AI to Drive Drug Discovery for Membrane Protein Targets
  Dr PC Biggin
Application Deadline: 11 January 2019
Lead supervisor. Prof Phil Biggin, Department of Biochemistry, Oxford. Commercial partner. Vertex Pharmaceuticals, Milton site, Oxfordshire.
  Fabrication of novel hybrid nano-carriers for pulmonary drug delivery
  Dr H Al-Obaidi
Applications accepted all year round
Pulmonary drug delivery is a non-invasive route for drug delivery where the lungs provide a thin, yet extremely efficient absorptive mucosal membrane with a good blood supply.
  Discovering new drugs for Mycobacterium abscessus infections in children
  Dr J Cox
Application Deadline: 27 January 2019
Applications are invited from candidates to undertake a PhD in the field of microbiology.
  MRC DiMeN Doctoral Training Partnership: Investigating copper storage in Pseudomonas aeruginosa and its role in pathogenicity
  Prof C Dennison, Dr A De Soyza, Prof C Winstanley
Application Deadline: 21 January 2019
Background. This interdisciplinary project bridges world-leading labs with expertise in bacterial cell biology and infection. Novel therapies are needed to overcome increasing antibacterial resistance.
  Characterising temperate bacteriophages in complex microbial communities and their role in antimicrobial resistance (Ref:SF18/APP/Smith)
  Dr D Smith
Applications accepted all year round
Temperate bacteriophages have the ability to integrate into the chromosome of their target bacterium that leads to a change in the physiology of their bacterial host.
  Experimental evolution of Pseudomonas aeruginosa in media replicating the conditions of the upper and lower airways
  Dr D Neill, Dr J Fothergill
Application Deadline: 20 January 2019
Pseudomonas aeruginosa (Pa) is an important bacterial pathogen in people with cystic fibrosis and other chronic lung conditions. During early infection, Pa adapts to the environment of the respiratory tract, leading to long-lasting, difficult to treat infections.
  Pyocins as alternatives to antibiotics against Pseudomonas aeruginosa infections
  Dr C Penfold
Applications accepted all year round
Pyocins are bacteriocins produced by Pseudomonas aeruginosa to kill closely related strains of the same species during times of environmental stress.
  The interaction of bacterial biofilms with immune cells.
  Dr L Martinez-Pomares
Applications accepted all year round
Second Supervisor. Miguel Camara/Paul Williams. Project Overview. P. aeruginosa (PA) is emerging as major opportunistic pathogen of clinical relevance.
  To experimentally determine the environmental influences acting on P. aeruginosa virulence factor expression in biofilms and understand the catalytic mechanism of one of them (the surface tethered aminopeptidase AaaA)
  Dr K Hardie
Applications accepted all year round
Pseudomonas aeruginosa is an important opportunistic pathogen. It is a problem for the immunocompromised and has attained superbug notoriety since it is evident in hospitals and has inherent resistance to antibiotics.
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