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We have 11 cystic fibrosis PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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cystic fibrosis PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 11 cystic fibrosis PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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SELF-FUNDING MSc BY RESEARCH PROJECT: Cystic fibrosis: restoring ion transport with small molecules

Cystic fibrosis (CF) is caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR), a unique ATP-binding cassette transporter that functions as an ATP-gated anion channel, playing a pivotal role in salt and water movement across epithelial tissues (1). Read more

Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more

Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more

Development of a personalized therapy for pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Investigating interactions between temperate bacteriophages and their bacterial hosts

Our research focuses on Bacteriophages (phages), which are viruses that infect and kill bacteria, but can also form partnerships as prophages, acting like internal puppet masters to change the fundamental biology of their bacterial hosts. Read more

Regulation of virulence and biofilm formation by quorum sensing and the "stress alarmone" ppGpp in gram-negative pathogenic bacteria.

We are investigating the complex interplay between cell-cell signalling (quorum sensing), microbial lifestyle (i.e., free-living planktonic cultures vs sessile biofilm communities), growth phase and virulence in gram-negative bacteria. Read more
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