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cytochrome PhD Projects, Programmes & Scholarships
We have 5 cytochrome PhD Projects, Programmes & Scholarships
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Understanding the interaction and functional mechanism of mitochondrial MIA pathway
Mitochondria are vitally important organelles of living cells, which generate the primary energy for all biological activities. Mitochondrial dysfunction leads to life threatening diseases, such as cancer, diabetes, stroke, and various neurodegenerative diseases (e.g. Read more
Evolution and biochemistry of photosynthesis - electron transfer reactions, renewable energy production, biotechnology, and chloroplast genomes
The common theme of our work is the biochemistry and evolution of photosynthesis. Read more
Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact
Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more
Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein
Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more
Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases
Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more
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