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cytochrome PhD Projects, Programs & Scholarships

We have 11 cytochrome PhD Projects, Programs & Scholarships

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Showing 1 to 10 of 11
  New ways to look at enzyme structures
  Dr P C E Moody, Dr J Basran
Application Deadline: 6 January 2019
Metal-catalysed activation of oxygen in biology is achieved using either copper or iron. In the case of iron, this includes the heme-containing enzymes which activate oxygen.
  Cytochromes P450 in Cancer: Opportunities for Development of Personalised Medicine - Project 2
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Prof P Loadman
Applications accepted all year round
The improved understanding of cancer biology provides opportunities for the development of molecular targeted therapies.
  Development of heterocyclic pharmacophores using diversity-oriented synthesis
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Prof L Patterson
Applications accepted all year round
Diversity-oriented synthesis (DOS) is a modern chemical tool, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression.
  Copper speciation and its impact on iron cycling
  Dr P Salaun, Dr A Tagliabue
Application Deadline: 23 January 2019
Motivation and wider context. Copper is a micronutrient required in a number of cellular processes that are key for phytoplankton growth [1].
  (BBSRC DTP CASE) Exploitation of P450 BM3 variants for production of valuable biomolecules
  Prof A Munro, Prof D Leys
Application Deadline: 31 January 2019
The US Food and Drug Administration (FDA) have recommended that many human drug metabolites (as well as their parent drugs) should be subject to testing for safety/toxicity.
  (BBSRC DTP CASE) High Pressure Biocatalysis: generating generic and scalable approaches to biocatalysis using engineered enzymes
  Dr S Hay, Prof A Munro
Application Deadline: 31 January 2019
Oxidation reactions play a key role in the bulk chemical industry and enzyme-mediated biocatalysis offers an alternative to the use of traditional catalysts, which can suffer from poor chemical selectivity and require the use of harsh reaction conditions and produce hazardous waste products.
  (BBSRC DTP) Biofuel synthesis from enzymes: how do charge distributions affect product control?
  Prof P Popelier, Dr S De Visser
Application Deadline: 31 January 2019
One of this project ‘s strengths is the novel computational technology it introduces to the paramount field of biocatalysis. Any quantum mechanical insight into enzymes is initially holistic in character, that is, energies and electron densities are calculated for the whole systems.
  Characterisation and engineering of novel and enhanced enzymes for the conversion of lignin biomass to high-value products
  Prof J McGeehan, Dr A Pickford, Dr G Beckham
Application Deadline: 24 February 2019
Applications are invited for a fully-funded three year PhD studentship to commence in October 2019.
  Molecular-genetic analysis of intra- and extra-cellular iron reduction systems in bacteria: role in gut colonisation and utilisation of dietary iron sources.
  Prof S C Andrews
Applications accepted all year round
The innate immune defense systems respond to bacterial infection by reducing the amount of available iron in order to restrict bacterial growth.
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