New ways to look at enzyme structures
Dr P C E Moody, Dr J Basran
6 January 2019
Metal-catalysed activation of oxygen in biology is achieved using either copper or iron. In the case of iron, this includes the heme-containing enzymes which activate oxygen.
Development of heterocyclic pharmacophores using diversity-oriented synthesis
Institute of Cancer Therapeutics
Dr K Pors, Prof L Patterson
Applications accepted all year round
Diversity-oriented synthesis (DOS) is a modern chemical tool, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression.
Copper speciation and its impact on iron cycling
Dr P Salaun, Dr A Tagliabue
23 January 2019
Motivation and wider context. Copper is a micronutrient required in a number of cellular processes that are key for phytoplankton growth .