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cytokine PhD Projects, Programs & Scholarships

We have 18 cytokine PhD Projects, Programs & Scholarships

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  Developing a three-dimensional research model of neutrophil-mediated tissue destruction during inflammation
  Dr J Hirschfeld, Prof I L C Chapple, Dr M Grant
Applications accepted all year round
Background. The proposed research has the goal to develop a novel 3D model to measure and visualise tissue destruction mediated by migrating neutrophils in vitro.
  (WIS) The role of IL1 and inflammasome activation in behavioural manifestations in neurological lysosomal disease progression
  Dr B BIgger, Dr D Brough
Application Deadline: 15 February 2019
Childhood dementia is a hallmark of around 2/3 of pediatric lysosomal storage disorders, together having a frequency of around 1/5500 live births.
  The interaction of bacterial biofilms with immune cells.
  Dr L Martinez-Pomares
Applications accepted all year round
Second Supervisor. Miguel Camara/Paul Williams. Project Overview. P. aeruginosa (PA) is emerging as major opportunistic pathogen of clinical relevance.
  Tumour microenvironment and colorectal cancer development: understanding the mechanisms of the tumour growth
  Prof D Kerr, Dr S Cai
Application Deadline: 26 July 2019
Our group has conducted a series of international adjuvant trials of chemotherapy for colorectal cancer (Kerr RS. et al, (2016), Lancet Oncol, 17, 1543 – 1557).
  Investigating inflammasome regulation in human myeloid cells
  Research Group: Centre for Experimental Medicine
  Dr R Coll, Prof P Moynagh
Application Deadline: 20 January 2019
Inflammasomes are protein complexes that control inflammation in both infection and sterile injury. Aberrant inflammasome activation is a driver of many diseases including.
  The role of long non coding RNA in the pathology of osteoarthritis joint disease
  Dr S Jones, Prof J Lord
Applications accepted all year round
This project will focus on determining the role of “long non coding RNA” in osteoarthritis (OA). OA is a painful joint condition and a leading causes of disability in the world.
  The effects of androgenetic alopecia development on immune function
  Research Group: Centre for Skin Sciences
  Prof K McElwee, Dr M J Thornton
Applications accepted all year round
Androgen hormones can have significant effects on hair follicles in androgen sensitive regions of the scalp, beard, and other areas of skin.
  To determine the role of PGD2/CRTh2 axis on non-classical monocytes in asthma
  Prof C Brightling, Dr A Wright
Applications accepted all year round
PGD2 stimulation of non-classical monocytes is active in asthma and promotes T2-dependent memory/effector T cell responses. The Prostaglandin D2 / prostaglandin D2 receptor (also known as CRTh2) axis plays an important role in allergic and Type 2 (T2)-mediated moderate to severe asthma [1-3].
  Development of treatment for Osteoarthritis by blocking metalloproteinases
  Prof G Bou-Gharios
Applications accepted all year round
MMP13 (collagenase 3) plays a vital role in the pathogenesis of osteoarthritis (OA) because MMP13 preferentially cleaves type II collagen, the main component of cartilage, and both MMP13 levels and enzymatic activity are enhanced in OA.
  The role of neuromuscular junction (NMJ) degeneration in age-related loss of skeletal muscle mass and function
  Prof MJ Jackson, Prof A McArdle, Dr A Vasilaki
Applications accepted all year round
The NMJ (or motor endplate) is a highly specialised chemical synapse that transmits action potentials from motor neurons to muscle fibres.
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