Non-canonical G protein signalling of US28 as a new target for glioblastoma
Centre for Experimental Medicine
Dr B Plouffe, Dr E Evergren, Prof C Taggart
20 January 2019
Glioblastoma (GBM) is a very aggressive type of brain cancer with an extremely poor prognosis. For most of GBM cases, infection by the human cytomegalovirus (HCMV) expressing the chemokine receptor US28 is responsible of this disease.