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cytoskeleton PhD Projects, Programmes & Scholarships

We have 13 cytoskeleton PhD Projects, Programmes & Scholarships

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We have 13 cytoskeleton PhD Projects, Programmes & Scholarships

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Unlocking the potential of a novel microtubule growth inhibitor as a cancer therapeutic

Microtubules are a functionally versatile and critically important component of the cytoskeleton and as a result have been one of the most actively pursued therapeutic targets of the past 60 years. Read more

Modelling cross-linked fibre networks in flow

  Research Group: School of Computing
Many industrial and biomedical materials consist of a fibrous solid phase immersed in a viscous fluid, e.g. the cellular cytoskeleton, tissue engineering scaffolds, medical filters, fibre reinforced materials etc. Read more

Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.

Lung cancer is the largest cause of cancer-related deaths in the UK and worldwide. While little progress has been made in long-term survival rates, we now have a good understanding of the genetic drivers raising the prospect of earlier diagnosis and more effective treatments. Read more

THE HARD FACTS ABOUT VASCULAR INFLAMMAGING: Role of vascular stiffness on vascular smooth muscle cell inflammatory phenotype

ABSTRACT. Chronic inflammation is a major factor in the initiation and progression of many cardiovascular pathologies, including atherosclerosis, abdominal aortic aneurysms, and pulmonary artery hypertension. Read more

How does paclitaxel kill cells and why do some cells evade it?

Paclitaxel (Taxol) is a microtubule-stabilizing drug widely used for the treatment of breast, ovarian and lung cancers. For many years, it was thought to kill cancer cells by inducing mitotic arrest, thus preventing proliferation. Read more

Cell biology and evolution of cancer metastasis

We are interested in the spread of cancer, a process called metastasis. Metastasis is responsible for the majority of cancer deaths and there are currently no effective treatments to stop this process. Read more
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