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cytoskeleton PhD Projects, Programs & Scholarships

We have 41 cytoskeleton PhD Projects, Programs & Scholarships

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  Bactofilins and the bacterial cytoskeleton
  Dr E Hoiczyk
Applications accepted all year round
Newly developed light and electron microscopy methods are revolutionising our understanding of bacterial cells. Once thought to be simple, bacteria have now been recognised at highly organised cells using many elements previously only known from eukaryotes.
  Investigate a novel, unexplored link between WNT signalling and regulators of cell migration in cancer progression using CRISPR-Cas9 and advanced live cell imaging.
  Dr M Krause
Applications accepted all year round
Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. WNT signalling is a key pathway controlling morphogenesis in embryos and it has been shown that perturbations of this pathway promote cancer progression.
  Novel microscopy approaches for investigating relation between the spatio-temporal dynamics of actin filaments and Ca2+ response patterns during T-cell activation
  Dr M Fritzsche, Prof M Dustin
Application Deadline: 11 January 2019
A pivotal event promoting adaptive immune responses is binding of antigens to antigen receptors and subsequent actin cytoskeleton reorganisations resulting in receptor microcluster (MC) formation, intracellular signalling, and ultimately immunological synapse (IS) formation.
  Molecular mechanism involved in building neuronal microtubule cytoskeleton
  Research Group: Institute of Cell Biology
  Dr D Cheerambathur
Application Deadline: 13 December 2018
Neurons are highly polarized cells with two structurally and functionally distinct projections emanating from their cell bodies— the axon and the dendrites.
  Cell polarity regulation in a model eukaryote.
  Research Group: Institute of Cell Biology
  Prof K E Sawin
Application Deadline: 13 December 2018
Cells build and maintain their normal architecture and organisation through internal and external cues and landmarks. At the same time, cell organisation can change in a coordinated way in response to external stresses, either to effect changes in architecture or to achieve homeostasis at the level of the entire cell.
  Mechanisms regulating cell shape and architecture in health and disease.
  Research Group: Institute of Cell Biology
  Dr J Welburn, Dr T Ly
Application Deadline: 13 December 2018
Much research on cell organization has been using tissue culture epithelial or fibroblast cells. However, many other types of cells have a unique cellular organization tailored to their function.
  (BBSRC DTP)Understanding structure and function of the mechanosensors talin and vinculin
  Dr C Ballestrem, Prof C Baldock, Dr A Roseman
Application Deadline: 31 January 2019
Any aberration in the cells’ ability to sense their environment leads to severe health deficiencies including cancer, deficiencies in wound-healing and inflammation.
  Investigation of the generation of force by fibroblasts under the influence of therapeutic ultrasound
  Dr M Bass
Application Deadline: 23 January 2019
"Chronic ulcers are non-healing wounds that affect 200,000 UK patients annually and frequently result in amputation.
  Identifying the causes and cellular effects of Focal segmental glomerulosclerosis (FSGS).
  Dr G Welsh, Prof M Saleem
Applications accepted all year round
A major factor in morbidity and mortality worldwide is end stage renal disease (ESRD). At least 10% of ESRD is caused by focal and segmental glomerulosclerosis (FSGS), a form of steroid resistant nephrotic syndrome.
  Molecular mechanisms controlling cardiac fibroblast proliferation during cardiac fibrosis
  Dr M Bond
Applications accepted all year round
Applicants are invited for a new self-funded PhD studentship to study the molecular mechanisms of cardiac fibrosis. Myocardial fibrosis is a significant global health problem associated with nearly all forms of heart disease.
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