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We have 24 degeneration PhD Projects, Programmes & Scholarships

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degeneration PhD Projects, Programmes & Scholarships

We have 24 degeneration PhD Projects, Programmes & Scholarships

Psychological intervention, cognitive training, functional rehabilitation and well-being in clinical populations with brain degeneration

The concept of human well-being is a fundamental aspect of our existence and is often particularly vulnerable upon diagnosis and/or progression of long-term neurological conditions for which there is no cure, such as Parkinson’s, Alzheimer’s and Huntington’s disease. Read more

Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more

The impact of microglia on dopaminergic synapses in Parkinson’s disease

Applications are invited for a 3.5-year funded PhD studentship in the group of Dr Anna Mallach in the Department of Brain Sciences, commencing during 2024/25 for a project to study The impact of microglia on dopaminergic synapses in Parkinson’s disease. Read more

Tackling ageing in the gut: investigating the contribution of macrophages in the intestinal stem cell niche to gut maintenance and repair

Ageing of the gut is an important contributor to multimorbidities of the elderly, including frailty, and mental decline. However, the specific cellular and molecular mechanisms driving gut degeneration with ageing and how these lead to specific clinical outcomes are still unclear. Read more

A versatile approach to targeting mechanosensitive deubiquitinating enzymes (DUBs) in tissue damage and chronic inflammation using Molecularly Imprinted Nanoparticle Inhibitors (MINIs).

Inflammation is an essential defence mechanism adapted by our bodies to eliminate damaged cells, irritants and pathogens. However, persisting inflammation that fails to resolve promotes or contributes to a number of chronic diseases including cancer, rheumatoid arthritis and musculoskeletal diseases. Read more
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Accelerating innovation in ultra-widefield retinal imaging analysis through the development of foundation models that expand the range of tractable downstream analysis tasks

Optos is a company that produces and provides devices for eye care professionals to diagnose and image retinal disorders and diseases, including retinal detachments and tears, glaucoma, diabetic retinopathy, and age-related macular degeneration. Read more

Investigating the role of Aquaporins in age related diseases

Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more
Last chance to apply

Understanding the links between neurodegenerative diseases and the human microbiota

Dementia is characterised as a syndrome associated with an ongoing decline of brain functioning, with symptoms including memory loss, a decline in mental sharpness, quickness and understanding, and difficulties in carrying out daily tasks. Read more

Applied optogenetics to study the influence of neuronal activity on neurodegeneration

Neurodegenerative diseases represent a significant and growing challenge to global health, affecting millions worldwide. Despite extensive research efforts, the underlying mechanisms of neurodegeneration are not fully understood, and there is a critical lack of effective treatments. Read more

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