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We have 19 degeneration PhD Projects, Programmes & Scholarships

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degeneration PhD Projects, Programmes & Scholarships

We have 19 degeneration PhD Projects, Programmes & Scholarships

Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more

Applied optogenetics to study the influence of neuronal activity on neurodegeneration

Neurodegenerative diseases represent a significant and growing challenge to global health, affecting millions worldwide. Despite extensive research efforts, the underlying mechanisms of neurodegeneration are not fully understood, and there is a critical lack of effective treatments. Read more

Fully Funded PhD Scholarship in Biomaterials Synthesis and Cartilage Tissue Engineering

Application(s) are invited from suitably qualified candidates for full-time funded PhD scholarship starting in September, 2024 affiliated to the School of Medicine at the University of Galway. Read more

Investigating the role of Aquaporins in age related diseases

Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more

Development of micro-incubator OCT/ OCE bioreactor system to engineer a robust musculoskeletal tissue model

Achieving adequate musculoskeletal tissue healing is one of the most challenging factors in the repair of orthopaedic tissues. The problem of hard-to-soft tissue fixation is the major cause of failure of replacement grafts and leads to further musculoskeletal degeneration e.g. Read more

A 3D-Printed Blood-Brain-Barrier-on-a-Chip for Agrochemical Permeability Studies – CASE Studentship

The blood-brain barrier (BBB) tightly regulates the flow of material between the bloodstream and the brain. One of the big problems faced by a range of sectors, from pharmaceuticals to agrochemicals, is understanding how compounds interact with and cross this barrier. Read more

Investigating a transplantable biomaterial for retinal cell regeneration: a promising treatment for degenerative retinal eye diseases

Replacing degenerate retinal cells with new ones using conventional biomaterials has thus far yielded limited success against degenerative retinal diseases, dry age-related macular degeneration (AMD) and subsequent geographic atrophy of the macula. Read more

Developing therapies targeting inflammation and dysfunctional matrix biology in neurological and ocular disease

We are seeking talented, motivated students with a passion for research in inflammation and matrix biology in the eye and brain to join our team co-led by Dr Lisa Hill https://www.birmingham.ac.uk/staff/profiles/clinical-sciences/hill-lisa.aspx and Dr Hannah Botfield https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/botfield-hannah.aspx. Read more

Common genetic origins of visual and neurocognitive disorders

There is emerging evidence that apparently distinct neurodegenerative diseases have common genetic origins. For example, genes such as ARMS2 and HTRA1, which are fundamental to regulating neuronal health, are implicated in both dementia and diseases of the retina (particularly age-related macular degeneration). Read more

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