The overall goal of the project is elaborating sustainable and up-scalable method for synthesis of thermoplastic cellulose derivatives using fully biobased reagents and mechanochemical action of reactive extrusion. Read more
A self-funded PhD position is available in the Fielding and Ismail research groups. We investigate unpaired electron species that play an important role in biological and materials chemistry. Read more
Time delays are often seen as a source of frustration — missed connections due to delayed flights, disrupted online gaming due to communication lags, or instability of dynamical systems due to tiny control loop delays. Read more
Fentanyl is a potent synthetic opioid that is fuelling an ongoing epidemic of drug overdose deaths in the US. Like other opioids, such as morphine, fentanyl and its derivatives act on the µ-opioid receptor (MOR), which is a key player in pain modulation. Read more
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more
Background. Tackling infectious diseases represents one of the major global societal challenges of the 21st century. The discovery of antibiotics led to a new era of infection medicine and is widely regarded as one of the most significant medical advancements in history. Read more
Dr Fabrizio Pertusati is looking for a PhD student to design synthesise and evaluate pharmacological chaperones for the treatment of congenital disorder of glycosylation. Read more
Cyclopentadienyl ligands and their derivatives are ubiquitous to modern organometallic and coordination chemistry, their ease of derivatisation offering… Read more
. The cornea, a dome-shaped, transparent tissue at the front of the eye, is crucial for vision. Corneal infections, such as bacterial keratitis (BK), are among the leading causes of unilateral blindness worldwide. Read more
This project is one of a number that are in competition for funding from the GW4 BioMed2 MRC Doctoral Training Partnership which is offering up to 21 studentships for entry in September 2025. Read more
The Madsen Lab is dedicated to a systems understanding of PI3K signalling plasticity, inspired by observations from human disorders such as cancer and PIK3CA-related overgrowth spectrum (PROS) 1,2. Read more
Microplastics and fibres are widespread in the environment with significant work undertaken in marine environments looking at the fate and uptake of microplastics through the food chain. Read more
Our aim is to develop novel Positron Emission Tomography (PET) radiotracers for imaging the brain. PET is a non-invasive molecular imaging technique which enables visualization and quantification of various biological targets in vivo (e.g., receptor, enzyme). Read more
Human retroviruses are a group of pathogens infecting an estimated 50 million people worldwide. The most widespread human retrovirus is HIV-1, which remains a major cause of morbidity and mortality, particularly in developing countries. Read more
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