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differentiation PhD Projects, Programs & Scholarships

We have 95 differentiation PhD Projects, Programs & Scholarships

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  Integrative statistical inference methods for eukaryotic gene regulation with applications to embryonic stem cell differentiation
  Dr I Iqbal, Prof M Rattray, Prof A Sharrocks
Applications accepted all year round

Funding Type

PhD Type

Embryonic stem cells (ESCs) can differentiate into different cell types through intermediary cell states and deeper understanding of the regulatory control underlying these differentiation stages is a very important topic in the study of mammalian development (Yang et al., 2014 & 2019).
  (MRC DTP) Regulatory chromatin and transcriptional networks impacting on embryonic stem cell differentiation
  Prof A Sharrocks, Prof M Rattray
Application Deadline: 15 November 2019

Funding Type

PhD Type

Embryonic stem cells (ESCs) can give rise to all of the cells in the body so a detailed understanding of how they commit to other cell fates is fundamentally important to understanding both normal human developmental processes and how developmental defects arise.
  A potential role for Epithelial Mesenchymal Trans differentiation (EMT) in the Pathogenesis of Periodontal Disease
  Prof PR Cooper, Dr M Milward
Applications accepted all year round

Funding Type

PhD Type

Periodontitis is a ubiquitous chronic inflammatory disease that destroys the supporting structures of teeth; the most common form is chronic periodontitis which if untreated results in the breakdown of soft tissues and bone, ultimately leading to tooth loss.
  Homeostatic mechanisms in human urothelium: balancing of tissue regeneration and differentiation with implications for regenerative medicine and cancer
  Prof J Southgate
Application Deadline: 30 June 2020

Funding Type

PhD Type

The urothelium is the self-regenerating epithelium that lines the bladder, where it is highly specialised to function as a urinary barrier.
  Deciphering the principles underlying specification of endoderm versus mesoderm in mouse embryonic stem cells
  Dr C Hill
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Caroline Hill’s Group based at the Francis Crick Institute (the Crick). Our lab focuses on the transforming growth factor beta (TGF-b) superfamily of ligands which comprises the TGF-bs, Activins, Nodal, BMPs and GDFs.
  (STFC DTP) The Halogen Budget of Asteroid 4 Vesta
  Research Group: Isotope Geochemistry & Planetary Science
  Dr B O'Driscoll, Dr P Clay, Prof R Burgess, Dr R Garwood
Application Deadline: 4 December 2019

Funding Type

PhD Type

Asteroid 4 Vesta is the second largest body in the Asteroid Belt, second to the dwarf planet Ceres. Unlike most asteroids, but similar to Earth, Vesta is differentiated into a silicate crust, mantle and core.
  Understanding the gene regulatory landscape of embryonic stem cells and cancer cells
  Prof A Sharrocks, Prof M Rattray
Applications accepted all year round

Funding Type

PhD Type

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity.
  Developing pluripotent stem cell models of inherited retinal diseases
  Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Background. Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide.
  Investigation of the generation of force by fibroblasts under the influence of therapeutic ultrasound
  Dr M Bass
Applications accepted all year round

Funding Type

PhD Type

"Chronic ulcers are non-healing wounds that affect 200,000 UK patients annually and frequently result in amputation.
  Modeling differentiation of human embryonic stem cells and induced pluripotent stem cells into endodermal derivatives
  Prof A Adamo
Applications accepted all year round

Funding Type

PhD Type

The Laboratory of Stem Cells and Diseases (STEMD-Lab) is seeking a highly motivated candidate to develop a project based on the use of human embryonic stem cells (hES) and induced pluripotent stem cells (iPSCs) to derive glucose sensitive differentiated cell types (i.e.
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