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We have 743 disease PhD Projects, Programmes & Scholarships

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disease PhD Projects, Programmes & Scholarships

We have 743 disease PhD Projects, Programmes & Scholarships

Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies. We are interested in the regulatory pathways that control cell proliferation and cell migration and the events that disrupt this control in multiple types of cancer. Read more

Understanding how electrical communication can regulate metabolic cycles in bacteria biofilms

Project Overview. A biofilm is a robust form of bacteria colony resistant to antibiotics. They have significant impacts on a multitude of industries impacting health and industrial processes such as in food production and water security. Read more

Intestinal Microbiome Modulation using Next Generation Probiotics

We are seeking talented, motivated students with a passion for research in microbiology, gastrointestinal health and probiotic delivery led by Dr Richard Horniblow (Associate Professor in Gastrointestinal Biomedical Science) at the College of Medical and Dental Sciences and the University of Birmingham (https://www.birmingham.ac.uk/staff/profiles/clinical-sciences/horniblow-richard.aspx). Read more

Role of RyR2 posttranslational modification in arrhythmias

Cardiac arrhythmias remain the leading cause of death in patients with heart disease. An important trigger for arrhythmias is the inappropriate opening of the cardiac ryanodine receptor (RyR2). Read more

Epigenomic transcriptomic mechanisms underlying human neuropsychiatric and neurodegenerative diseases

This project aims to use high throughput sequencing technologies and molecular approaches to understand how RNA epitranscriptomic processes contribute to susceptibility to human disorders of the brain. Read more

Exosome biogenesis and organelle trafficking in neurodegeneration.

Scientific summary. Intracellular transport pathways are fundamental for cell structure and function. Due to their longevity, complex morphology (long axonal and dendritic extensions) and requirement to maintain synaptic transmission, neurons are heavily dependent upon intracellular transport. Read more

How do hormones regulate memory?

Deficiencies of thyroid hormone are common throughout the globe. Adult-onset hypothyroidism is prevalent in around 8-10% of the population and is associated with reproductive disorders, anxiety, depression and impairment of memory. Read more

Novel strategies for the diagnosis and treatment of snakebites

Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more

The role of selective and novel biomarkers and their correlation with clinical outcome measures, pre and post-surgical treatment of benign and malignant disorders of the prostate

The Maelor Academic Unit of Medical & Surgical Sciences (MAUMSS) is a novel initiative by the Betsi Cadwaladr University Health Board (BCUHB), and is designed to encourage and support research within the Health Board and to promote academic activity, basic science and clinical research across North Wales (UK) and beyond. Read more

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