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We have 565 drug PhD Projects, Programmes & Scholarships

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drug PhD Projects, Programmes & Scholarships

We have 565 drug PhD Projects, Programmes & Scholarships

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Precision Medicine DTP - Genetic colocalisation across disease to identify drug repurposing candidates and risk of patient co-morbidities

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: Centre for Inflammation Research
Background. Discoverying new drugs is expensive, time intensive and fraught with failure at all stages (1). An attractive alternative, with much lower costs and faster development timelines, is to find new applications for already approved drugs, a process known as drug repurposing or drug reallocation. Read more
 Supervisors: Dr E Pairo-Castineira, Mr K Rawlik, Dr K Baillie
 15 January 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DTP - AI-driven drug discovery for diseases of unmet need with high-throughput phenomics data

University of Edinburgh School of Informatics
Abstract. Drug discovery is extremely expensive and most candidate compounds fail at various stages of clinical trials. Artificial Intelligence (AI) has recently emerged as a promising tool to accelerate the search for new active compounds. Read more
 Supervisors: Dr D Oyarzun, Prof N Carragher, Dr A Unciti-Broceta
 15 January 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

Queen’s University Belfast School of Pharmacy
One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more
 Supervisor: Dr G Laverty
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MRC DiMeN Doctoral Training Partnership: Development of novel cold atmospheric plasma-mediated drug delivery for targeted anti-cancer therapy

University of Sheffield MRC DiMeN Doctoral Training Partnership
Background. Oral squamous cell carcinoma (OSCC) has risen by 60% in the last decade. This cancer is currently treated by surgery followed by radio- or chemotherapy. Read more
 Supervisors: Dr H Colley, Prof RS Short, Prof K Hunter
 17 December 2023  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Identifying Mechanisms of Tyrosine Kinase Inhibitor Resistance in Breast/Cervical Cancer (with emphasis on FGFR)

Kingston University Faculty of Health, Science, Social Care and Education
Introduction   . FGF signalling is implicated in cancer (e.g., breast and cervical cancer) susceptibility and progression, suggesting that this powerful developmental pathway is co-opted by cancer cells. Read more
 Supervisor: Dr A Chioni
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Integrative data analysis: from novel biomarker-drug response associations to predicting effective drug combinations

Children’s Cancer Institute Australia Centre for Childhood Cancer Research
  Research Group: Translational Tumour Biology
More than 140 children with cancer die in Australia each year due to the occurrence of resistance to traditional chemotherapy. To improve overall survival rates for high-risk paediatric cancer patients, the Children’s Cancer Institute initiated the Zero Childhood Cancer national personalised medicine trial (PRISM). Read more
 Supervisors: Dr E Dolman, Assoc Prof P Ekert
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Investigating the Mechanisms of Drug Response to Novel Anti-Cancer Therapies

Queen’s University Belfast School of Pharmacy
Repurposing drug screens with compounds that have already gained FDA approval can accelerate the identification of new therapies to treat an illness and in the cancer setting extend life or provide compassionate care. Read more
 Supervisor: Dr F Furlong
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Nanotechnologies for cancer: developing new polymer-drug conjugates for the treatment of a range of cancers

University of Reading School of Pharmacy
Polymer anticancer-drug conjugates are drug delivery systems in which a low molecular weight anticancer agent is covalently conjugated to a water-soluble polymeric carrier. Read more
 Supervisors: Dr F Greco, Prof H Osborn
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mechanistic design of effective pharmaceutical cocrystal formulations

Newcastle University Faculty of Medical Sciences Graduate School
It is estimated that more than 70 percent of the compounds in the pharmaceutical pipeline can be poorly water-soluble. Since solid drug forms must dissolve before absorption can occur, strategies to improve drug solubility and dissolution are a continuous need. Read more
 Supervisor: Ms T C M Machado
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mathematical modelling for preclinical drug trials: small molecule drugs and antibody drug conjugates

University of Surrey School of Mathematics and Physics
Preclinical evaluation of drug efficacy plays a fundamental role in the development of cancer treatments. Mathematical modelling is fundamental to these preclinical studies, specifically to describe the tumour dynamics and evaluate the anti-tumour effect. Read more
 Supervisor: Dr C Dunlop
 1 March 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Developing a novel drug screening platform for schistosomes using the free-living flatworm Schmidtea mediterranea

Kingston University Faculty of Health, Science, Social Care and Education
Schistosoma mansoni is one of three major schistosome species that infect over 240 million people across 70 developing countries, with an additional 0.6 billion at risk of infection. Read more
 Supervisor: Dr E Shakir
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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ACS-08-Damian - Capsule Robot Pharmacy: The Future Personal Gastrointestinal Medication Dispensary

University of Sheffield Department of Automatic Control and Systems Engineering
In this research project, our primary objective is to pioneer the development of cutting-edge therapeutic technology. an in-the-body mobile pharmacy designed for autonomous drug management. Read more
 Supervisor: Dr D Damian
 24 January 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School
Rationale. Mendelian Randomization (MR) is a genetic epidemiology method which utilises variants sourced from genome-wide association studies (GWAS) to assess causality between risk/protective factors and disease outcomes in a manner less biased to observational studies(1). Read more
 Supervisors: Prof T Gaunt, Dr M Sobczyk
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more
 Supervisors: Dr S Shnyder, Dr S Kantamneni
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

University of Leeds Faculty of Biological Sciences
  Research Group: Astbury Centre for Structural Molecular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more
 Supervisors: Prof A O'Neill, Dr M McPhillie, Prof C Fishwick
 Open Day(s)  Year round applications  PhD Research Project  Self-Funded PhD Students Only
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