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We have 161 drug analysis PhD Projects, Programmes & Scholarships

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drug analysis PhD Projects, Programmes & Scholarships

We have 161 drug analysis PhD Projects, Programmes & Scholarships

Precision Medicine DTP - Genetic colocalisation across disease to identify drug repurposing candidates and risk of patient co-morbidities

  Research Group: Centre for Inflammation Research
Background. Discoverying new drugs is expensive, time intensive and fraught with failure at all stages (1). An attractive alternative, with much lower costs and faster development timelines, is to find new applications for already approved drugs, a process known as drug repurposing or drug reallocation. Read more

Integrative data analysis: from novel biomarker-drug response associations to predicting effective drug combinations

  Research Group: Translational Tumour Biology
More than 140 children with cancer die in Australia each year due to the occurrence of resistance to traditional chemotherapy. To improve overall survival rates for high-risk paediatric cancer patients, the Children’s Cancer Institute initiated the Zero Childhood Cancer national personalised medicine trial (PRISM). Read more

Investigating the Mechanisms of Drug Response to Novel Anti-Cancer Therapies

Repurposing drug screens with compounds that have already gained FDA approval can accelerate the identification of new therapies to treat an illness and in the cancer setting extend life or provide compassionate care. Read more

Fully Funded PhD Scholarship in Antibody Drug Conjugate (ADC) analysis by Polarized Excitation Emission Matric (pEEM) spectroscopy, NBL-3

Application(s) are invited from suitably qualified candidates for full-time funded PhD scholarship(s) starting in February 2024 affiliated to the Nanoscale Biophotonics Laboratory in the Discipline of Physics (School of Natural Sciences) at the University of Galway. Read more

Precision Medicine DTP - AI-driven drug discovery for diseases of unmet need with high-throughput phenomics data

Abstract. Drug discovery is extremely expensive and most candidate compounds fail at various stages of clinical trials. Artificial Intelligence (AI) has recently emerged as a promising tool to accelerate the search for new active compounds. Read more

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Polysialyltransferases as a target in metastatic cancer

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more

Precision Medicine DTP - Combining deep mutational scanning and imaging to explain mutation pathogenicity and drug resistance in tubulins

  Research Group: MRC Human Genetics Unit
Background. Microtubules, dynamic polymers composed of alpha and beta-tubulin subunits, are integral components of eukaryotic cells and are functionally conserved in bacteria through related essential cytoskeletal elements. Read more

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