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drug design PhD Projects, Programs & Scholarships

We have 157 drug design PhD Projects, Programs & Scholarships

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  Computer-aided molecular design: improved ligand docking using electronic structure and molecular dynamics simulations
  Dr R A Bryce, Dr N Burton
Applications accepted all year round

Funding Type

PhD Type

In structure-based drug design, computational modelling techniques are frequently used to predict the orientation and affinity with which a ligand binds to its protein receptor.
  Construction of QSAR models for searching multi-target drug hits beyond similarity-based applicability domains
  Dr X Liu, Dr J Meng, Prof F Falciani
Applications accepted all year round

Funding Type

PhD Type

Drugs designed to act against individual molecular targets cannot usually combat multigenic diseases such as cancers in which alternative or compensatory pathways are often activated.
  In vitro assessment of drug sequestration into lysosomes and in silico prediction of implications for drug disposition and therapeutic efficacy
  Dr A Galetin, Dr D Hallifax
Applications accepted all year round

Funding Type

PhD Type

Intracellular concentration of a drug is an important determinant of its efficacy, toxicity, and potential drug-drug interactions [1].
  Combined use of in-vitro and in-silico models for drug discovery
  Dr I Khadra, Prof G Halbert
Application Deadline: 1 June 2020

Funding Type

PhD Type

This project is one of 16 four year PhD Studentships funded by Medical Research Scotland (https://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and External Partner Organisation (EPO).
  Modular design of custom protein structures
  Dr F Parmeggiani
Applications accepted all year round

Funding Type

PhD Type

Proteins perform most of the functions in biological systems, from structural support, to movement, communication and catalysis. Our goal is to use modular building blocks to quickly and precisely design novel protein nanomaterials and nanoparticles to control cell behaviour.
  How can public support be fostered for controversial, but evidence-based, drug policies that will improve outcomes for stigmatised and marginalised groups?
  Dr H R Sumnall, Dr A Atkinson, Dr S Gage, Dr I Hamilton
Applications accepted all year round

Funding Type

PhD Type

The UK is currently facing some of the highest levels of deaths related to controlled drug use on record. People who use drugs (PWUD) also face other health and social harms related to their drug use, and because of the ways in which society chooses to respond to their drug use.
  MSc by Research Programme: Development of novel therapeutics against parasitic disease
  Prof M Field
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  EPSRC Centre for Doctoral Training in Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research - SABS

Funding Type

PhD Type

Good degree in the Physical or Life Sciences? Interested in biological or medical research? We offer fully-funded PhD places across the Oxford Doctoral Training Centre programmes.
  Nanotechnologies for cancer: developing new polymer-drug conjugates for the treatment of a range of cancers
  Dr F Greco, Prof H Osborn
Applications accepted all year round

Funding Type

PhD Type

Polymer anticancer-drug conjugates are drug delivery systems in which a low molecular weight anticancer agent is covalently conjugated to a water-soluble polymeric carrier.
  Exploiting druggability host spots in protein phosphatase targets
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Applications accepted all year round

Funding Type

PhD Type

In the past years the use of virtual screening or computer-based screening of compound libraries against selected targets has expanded exponentially the boundaries of drug discovery.
  Discovery of novel cancer immunotherapeutic agents
  Dr Y Mehellou
Applications accepted all year round

Funding Type

PhD Type

Although cancer therapeutics, mainly chemotherapy and radiotherapy, have been extremely useful in the treatment of cancer, this disease is still associated with high morbidity and mortality.
  Deep Learning / Bioinformatics Approach for Protein-Protein Interaction Prediction
  Dr JC Nebel
Applications accepted all year round

Funding Type

PhD Type

Since most molecular processes rely on protein–protein interactions PPIs), knowledge of those interactions is extremely valuable for biomedical research and drug design.
  Accurate energy evaluation of receptor-ligand interaction
  Prof P Popelier, Dr S De Visser
Applications accepted all year round

Funding Type

PhD Type

Drug design routinely uses existing computational methods to evaluate the interaction energy between receptor (protein) and ligand (drug) in molecular docking.
  Developing novel drugs targeting gut microbiota-accelerated heart diseases
  Dr Y Chen, Prof T Bugg, Dr A Cameron
Application Deadline: 7 June 2020

Funding Type

PhD Type

It is increasing evident that human is a “super-organism”. We co-exist with trillions of microorganisms in our body (collectively named as microbiota), and our health can largely depend on the interrelationship between ourselves and associated microbiome.
  Phytopharmacology of Polar Auxin Transport
  Prof Richard Napier, Dr A Cameron, Dr M Wall
Application Deadline: 7 June 2020

Funding Type

PhD Type

Polar transport of hormones lays down patterning in plants. Polar auxin transport is mediated by PIN proteins which are plasma membrane-bound transporters.
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