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We have 71 drug design and development PhD Projects, Programmes & Scholarships

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drug design and development PhD Projects, Programmes & Scholarships

We have 71 drug design and development PhD Projects, Programmes & Scholarships

Mechanistic design of effective pharmaceutical cocrystal formulations

It is estimated that more than 70 percent of the compounds in the pharmaceutical pipeline can be poorly water-soluble. Since solid drug forms must dissolve before absorption can occur, strategies to improve drug solubility and dissolution are a continuous need. Read more

Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

Discovery of Novel Cancer Immunotherapeutic Agents

Summary. Although cancer therapeutics, mainly chemotherapy and radiotherapy, have been extremely useful in the treatment of cancer, this disease is still associated with high morbidity and mortality. Read more
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Design and synthesis of a hybrid compound of RAR and VDR

The doctoral candidate (DC) will perform chemical research on the design and organic synthesis of hybrid compounds at the Medical University of Warsaw, Warsaw, Poland. Read more

Discovery of New Treatments for Parkinson’s disease

Summary. Parkinson’s disease (PD) is the second most common neurological disease in the world. Current PD therapies and medical interventions are very limited and only address the symptoms of this disease highlighting the need for new and effective treatments for this disease. Read more

Novel design and formulation strategies to enhance drug delivery

The main research activities of my research group concern the improvement of traditional drug formulation and development of novel drug and formulation strategies to enhance bioavailability and patient acceptability. Read more

Understanding Hormone Regulation in Skin Cancer Development and Progression

Skin cancers, including melanoma and non-melanoma skin cancers, pose a significant global health burden. While the role of hormones in skin cancer development and progression remains an underexplored area, recent research has suggested potential links between hormonal regulation and skin cancer outcomes. Read more

Developing biodegradable long acting drug delivery systems for the treatment of chronic conditions

Non-adherence to treatment costs the NHS more than £500M each year. Adherence is especially important when treating patients with chronic conditions that require lifetime pharmacological treatment, such as schizophrenia, Parkinson’s disease, HIV and Alzheimer’s disease. Read more

Towards the development of a novel class of broad-spectrum anti-infective drugs

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more

Microfluidic Encapsulation of biologics into Nanomedicines

Progress in drug design has led to the development of new peptides, proteins, and drug molecules. However, the limited ability to deliver selectively these molecules at well-defined dosing regimens and without invoking drug-resistance remains a significant challenge. Read more

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