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drug development PhD Projects, Programmes & Scholarships
We have 203 drug development PhD Projects, Programmes & Scholarships
We have 203 drug development PhD Projects, Programmes & Scholarships
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Drug Development Informatics: a framework to support the analysis of large-scale simulations
Drug resistant infections are already on the rise with numbers suggesting that up to 50,000 lives are lost each year to antibiotic-resistant infections in Europe and the US alone. Read more
Antimicrobial drug development: Synthesis, characterisation, and evaluation of novel antimicrobial agents to combat antimicrobial resistance.
Vaccines and antibiotics have been at the forefront in the prevention and treatment of infectious diseases. However, the indiscriminate use of antibiotics has led to the development of antimicrobial resistance (AMR). Read more
Using structural biology to develop drugs and improve genetic testing for polycystic kidney disease
Are you looking for a PhD in structural and computational biology applied to drug development for human diseases?. Read more
Studies of complex biomolecular systems using advanced biochemical and biophysical techniques
The project, led by. Associate Professors Mehdi Mobli. and. Jeffrey Harmer. , aims to develop new tools to reveal the structure and dynamics of complex protein systems within their native environment by combining innovative biochemistry, new magnetic resonance spectroscopy and high performance computing. Read more
3D Printing in the Preclinical space vs. Late Development
3D Printing (3DP) provides many advantages for preclinical drug product development as a wide dose range can easily be manufactured/printed, multiple prototypes can be manufactured quickly, adjusting release profiles and drug product geometries. Read more
Laser Spectrometry Development for Isotopic Analysis in Environmental and Medical Applications
Summary. This is a fully-funded PhD opportunity based at NPL (London) that will investigate and establish laser spectrometry for measurement of stable isotope ratios and radiocarbon in carbon dioxide and methane, relevant for environmental monitoring and drug discovery applications. Read more
Development of pulmonary dosage forms for improved antibacterial activity
"Conventional formulations for drug delivery to the lungs are limited to less than a few milligrams as a fine particle fraction. Read more
Mechanistic models for protein binding and transport in organ impairment
When evaluating impact of disease on drug response, measurement of total drug concentration is typically used as surrogate for free drug concentration and pharmacological effect. Read more
Exploration of Amorphous solid dispersion systems with multiple APIs
A number of formulation strategies have been developed to improve the delivery of Biopharmaceutical Classification System (BCS) II and IV class drugs. Read more
Robotic Manipulation of Cells and Intracellular Structures
Advances in Biology and medicine demand robotic technologies for automated manipulation and characterization of cells and sub-cellular structures. Read more
Medicinal Chemistry Project: Synthesis of novel small molecules for the potential treatment of the asbestos induced lung cancer mesothelioma
The Project. In developing a new therapeutic agent, there are two questions to address. how to get the potential drug to the specific site in the body where it is needed and second, does it do what we want it to do at the target site and without undesirable side effects. Read more
Cardiac modelling allows us to understand how healthy and diseased hearts work.
Heart failure is the inability of the heart to efficiently deliver oxygen around the body. Heart failure affects more than 26 million people worldwide. It has multiple causes, including hypertrophic heart, enlarged compartments, etc, when the heart can’t adequately pump and deliver blood and oxygen around the body. Read more
Selective drug uptake by cell surface transporters
Cell surface transporters and not diffusion is responsible for the transfer of metabolites across a cell’s membrane. Many types of drugs are structurally very similar to natural metabolites and as a consequence they are treated by the cell as though they are the natural homologue. Read more
Development of peptide hydrogel as an anticancer drug carrier
Growth in nanotechnologies can now be exploited to enable engineering of new drug delivery systems for enhancing the entrapment of drugs in nano-sized structures with tailored physical properties to suit therapeutic need. Read more
EN & MN Lindsay Scholarship: Computer-aided drug discovery (CADD) methodologies for the identification and optimisation of bioactive compounds
We invite applications to this project for a fully funded four-year EN & MN Lindsay Endowed PhD studentship. . Read more