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We have 195 drug development PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
drug development PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 195 drug development PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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Fully funded PhD Position in Model-Based Meta-Analysis for Drug Development
We are seeking a highly motivated and talented individual to join our team spanning between LSBU and GSK as a PhD student in the field of model-based meta-analysis for drug development. Read more
A high throughput human vascularised 3D in-vitro model of adipose tissue to replace animal testing in drug development for metabolic dysfunction
Obesity is a rising epidemic and a risk for many comorbid conditions such as type 2 diabetes, coronary artery disease, and some cancers. Read more
Development of long-acting injectable (LAI) drug delivery systems to treat ocular diseases
Delivery of drug molecules to treat visually impairing ocular diseases that originate in the posterior segment of the eye, has been the most challenging task to the pharmaceutical scientists and retinal specialists. Read more
Mechanistic models for protein binding and transport in organ impairment
When evaluating impact of disease on drug response, measurement of total drug concentration is typically used as surrogate for free drug concentration and pharmacological effect. Read more
Building a toxicological screen to predict drug-induced pulmonary hypertension (RANAA_U23MRC)
Pulmonary arterial hypertension (PAH) is a debilitating, often fatal disease, affecting both children and adults, which is caused by structural changes (vascular remodelling) of pulmonary blood vessels leading to their narrowing and obliteration (PMID:15194174). Read more
Enzyme-responsive peptide hydrogel as in situ forming long-acting drug delivery implants
One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more
Drug discovery for amyloid plaques based neurodegenerative disorders (ref: SF22/HLS/APP/MEERA)
Alzheimer’s disease (AD) followed by Parkinson’s Disease (PD) are the two most prominent causes of dementia that poses a huge health burden in an increasingly ageing population worldwide. Read more
Chemical glycoengineering of therapeutic antibodies
Glycosylation is the most common posttranslational protein modification. Recombinant therapeutic glycoproteins (RTGs) such as monoclonal antibodies (mAbs) are decorated with complex glycans that determine not only their efficacy but also other critical parameters such as in vivo half-life, stability and antigenicity. Read more
Selective drug uptake by cell surface transporters
Cell surface transporters and not diffusion is responsible for the transfer of metabolites across a cell’s membrane. Many types of drugs are structurally very similar to natural metabolites and as a consequence they are treated by the cell as though they are the natural homologue. Read more
MscR: Identification of effective drug combinations to inhibit SARS-CoV-2 variants of concern
Keywords. Bristol, Virology, SARS-CoV-2, Antivirals. Variants of concern remain a public health threat associated with SARS-CoV-2 infection. Read more
PhD Student - Development of stable chemically modified mRNA for vaccine applications
National Institute for Bioprocessing Research & Training
Department of Chemical and Bioprocess Engineering at University College Dublin
ORGANISATION OVERVIEW. The National Institute for Bioprocessing Research and Training (‘NIBRT’) is a global centre of excellence, headquartered in Dublin, Ireland that provides training and research solutions to the global biopharmaceutical manufacturing sector. Read more
Biomedical Engineering: Fully Funded Swansea University, EPSRC and Bruker-nano PhD Scholarship: Analysing the forces, biomechanics and molecular mechanisms that drive cancer metastasis in vitro
Funding providers: Swansea University's Faculty of Science and Engineering, Engineering and Physical Sciences Research Council (EPSRC) DTP and Bruker-nano. Read more
The use of Drosophila melanogaster to identify novel therapeutic agents for Alzheimer’s disease
Since 2003, our understanding of the causes of Alzheimer’s disease (AD) have improved considerably, however, in that time only one new drug treatment has been approved. Read more
Exploring the transcriptomic and chromatin landscapes of fibroblast-like synoviocytes in rheumatoid arthritis
Genetic studies in rheumatoid arthritis (RA) have been successful in identifying regions of the genome which contribute to disease risk, but it is often unclear which genes they effect. Read more
Safer, scalable, and modifiable polymer-based lipid nanocapsules for drug delivery
Lipid nanocapsules (LNCs) are very interesting nanoformulations as they can be made by phase inversion technique (PIT), a scalable method with predictable particle size at the beginning of the preparation process. Read more