MRC DTP 4 Year PhD Programme: Binding Affinity Prediction in Drug Discovery
Dr I H Gilbert, Prof P Wyatt, Dr F Zuccotto
18 January 2019
The major challenge in drug discovery is to develop a compound that is capable to interact with a biological target associated to the disease and has a good balance of physical and biological properties necessary to become an efficacious and safe drug.
A nanotechnology solution to one of drug discovery’s last challenges.
Prof T R Dafforn, Dr F Fernandez-Trillo
6 January 2019
Membrane proteins represent 30-40% of the cellular proteome and carry out a wide range of fundamental biological process. These include sensing the outside world, helping maintain cellular structure and homeostasis.