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drug metabolism PhD Projects, Programs & Scholarships

We have 29 drug metabolism PhD Projects, Programs & Scholarships

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  Design, synthesis and evaluation of MMP-activated anti-cancer prodrugs
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Prof P Loadman
Applications accepted all year round
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis.
  Transdermal and Topical Drug Delivery: developing novel formulations to increase drug delivery into and through skin
  Prof A Williams
Applications accepted all year round
Human skin is a remarkable self-repairing barrier that controls the ingress of environmental contaminants and regulates water loss from the body.
  Cytochromes P450 in Cancer: Opportunities for Development of Personalised Medicine - Project 2
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Prof P Loadman
Applications accepted all year round
The improved understanding of cancer biology provides opportunities for the development of molecular targeted therapies.
  Cytochromes P450 in Cancer: Opportunities for Development of Personalised Medicine - Project 1
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Prof P Loadman
Applications accepted all year round
The improved understanding of cancer biology provides opportunities for the development of molecular targeted therapies.
  The relationship between dietary iron and zinc, and the gut microbiota: Can dietary iron and zinc regime be exploited to improve health?
  Prof S C Andrews
Applications accepted all year round
"The gut microbiota (100 trillion cells) outnumber human cells by 10 to 1. Its composition of around 500 to 1000 species is specific for each individual and is dynamic, changing with age, health and diet.
  MRC DiMeN Doctoral Training Partnership: Antiretroviral-induced metabolic toxicity: Role of adipose- miRNAs as mechanistic regulators and toxicity biomarkers
  Dr S Pushpakom
Application Deadline: 21 January 2019
Supervisors. Dr S Pushpakom. Prof M Bushell. Prof Sir M Pirmohamed. Background. Diabetes, obesity and cardiovascular disease (collectively called cardiometabolic disease) remain a major public health problem worldwide.
  Use of novel technologies for reasoned identification of antifungal drug targets: sulphur metabolism in Aspergillus fumigatus.
  Prof E Bignell, Dr J Amich
Applications accepted all year round
Fungal diseases kill more than 1.5 million and affect over a billion people worldwide. Azoles are the only orally available antifungals and resistance to these drugs is increasing, which translates into a rise in mortality.
  Understanding drug-resistance in myeloid cancer
  Dr P Laslo
Applications accepted all year round
Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory.
  Using state-of-the-art proteomics to study the cellular and extracellular protein composition in human kidney disease; identification of novel biomarkers and bioactive drug targets in IgA Nephropathy
  Dr A Didangelos, Prof J Barratt
Applications accepted all year round
One of the key pathological characteristics of IgA nephropathy (IgAN) is the maladaptive and chronic accumulation and remodelling of the extracellular matrix (ECM) in affected glomeruli leading to fibrosis and progressive loss of function.
  Circadian control of energy metabolism and inflammation: Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, experimental medicine studies, CRISPR engineered mice, and cell biology
  Prof D Ray
Application Deadline: 11 January 2019
Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, experimental medicine studies, CRISPR engineered mice, and cell biology.
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