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"drug" AND "metabolism"×
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drug metabolism PhD Projects, Programs & Scholarships

We have 26 drug metabolism PhD Projects, Programs & Scholarships

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  Quantitative Allele-Specific Proteomics in Drug Metabolism and Disposition
  Dr J Barber, Dr B Achour, Prof A Rostami
Applications accepted all year round
The effective dose of a drug is subject to considerable inter-individual variation because the enzymes that metabolise drugs and the proteins that transport them in and out of cells exist, in many cases, in different polymorphic forms and are expressed in varying concentration.
  Optimising Drug Delivery to Targets within the Spleen by Understanding the Relationship Between Drug Structure and Drug Disposition
  Dr S Paine, Dr J Kaler
Application Deadline: 4 April 2019
The spleen is a key target organ for immunotherapy as it contains a high concentration of lymphocytes and macrophages. Drug interaction with these two cell types may have implications both in terms of therapeutic or toxic activity and in terms of drug disposition.
  Design, synthesis and evaluation of MMP-activated anti-cancer prodrugs
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Prof P Loadman
Applications accepted all year round
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis.
  Transdermal and Topical Drug Delivery: developing novel formulations to increase drug delivery into and through skin
  Prof A Williams
Applications accepted all year round
Human skin is a remarkable self-repairing barrier that controls the ingress of environmental contaminants and regulates water loss from the body.
  Cytochromes P450 in Cancer: Opportunities for Development of Personalised Medicine - Project 2
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Prof P Loadman
Applications accepted all year round
The improved understanding of cancer biology provides opportunities for the development of molecular targeted therapies.
  Cytochromes P450 in Cancer: Opportunities for Development of Personalised Medicine - Project 1
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Prof P Loadman
Applications accepted all year round
The improved understanding of cancer biology provides opportunities for the development of molecular targeted therapies.
  The relationship between dietary iron and zinc, and the gut microbiota: Can dietary iron and zinc regime be exploited to improve health?
  Prof S C Andrews
Applications accepted all year round
"The gut microbiota (100 trillion cells) outnumber human cells by 10 to 1. Its composition of around 500 to 1000 species is specific for each individual and is dynamic, changing with age, health and diet.
  Understanding drug-resistance in myeloid cancer
  Dr P Laslo
Applications accepted all year round
Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory.
  Circadian control of energy metabolism and inflammation: Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, experimental medicine studies, CRISPR engineered mice, and cell biology
  Prof D Ray
Application Deadline: 26 July 2019
Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, experimental medicine studies, CRISPR engineered mice, and cell biology.
  Application of advanced analytical methods to study key aspects of health and disease
  Prof D Naughton
Applications accepted all year round
Considerable advances in the analytical capabilities of modern techniques afford a new horizon in the study of health and disease.
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