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We have 80 drug resistance PhD Projects, Programmes & Scholarships

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drug resistance PhD Projects, Programmes & Scholarships

We have 80 drug resistance PhD Projects, Programmes & Scholarships

Decoding the epigenetic mechanisms of drug resistance in aggressive breast cancers

Breast cancers pose a major health burden to modern world as being the most common cancer in women. Estrogen receptor (ER), the classical marker of 70% these cancers, is the nuclear receptor important for cancer progression. Read more

Combatting multidrug resistance: Are alpha-arrestins attractive therapeutic targets to tackle Candida infections?

The opportunistic fungal pathogen Candida glabrata is a frequent cause of candidiasis, causing infections ranging from superficial to life-threatening disseminated disease, and is associated with high mortality, especially in immunocompromised individuals. Read more

Do nutrient availability and the extracellular matrix affect therapy response in cancer?

The tumour microenvironment (TME) plays a pivotal role in controlling cancer progression and response to therapy. A key component of the TME is the extracellular matrix (ECM), a complex network of secreted protein involved in controlling a variety of cell functions, including proliferation and migration. Read more

Cybergenetic control of living cells: a control-based approach to design new therapies

The project. Precision oncology promises to develop effective therapies tailored to the genetic profile of specific cancers. To achieve this goal, we still need to overcome drug resistance, which often arises in therapies targeting a single oncogenic driver. Read more

Nanoprecision in antibiotic delivery using targeted nanoparticles

Gram-negative bacterial species, including E. coli, are major causes of infectious diseases worldwide and account for all organisms in the “critical” category of the WHO list of antibiotic-resistant "priority pathogens". Read more

Fully funded PhD studentship in mechanisms of cancer heterogeneity and drug sensitivity

Treatment of cancer with drugs that cause DNA damage often leads to development of the drug tolerance. Recently, we uncovered a novel mechanism of such an adaptation that associates with active generation of hundreds of thousand mutations in chromosomes that prevent drug-triggered DNA damage. Read more

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