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drug resistance PhD Projects, Programmes & Scholarships

We have 108 drug resistance PhD Projects, Programmes & Scholarships

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We have 108 drug resistance PhD Projects, Programmes & Scholarships

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Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

  Research Group: Institute of Cancer Therapeutics
Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more
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EASTBIO: How do human fungal pathogens remodel their genome to acquire drug resistance?

  Research Group: Infection Medicine
Deanery of Biomedical Sciences. Fungal pathogens are a huge burden on human health, killing almost 2 million people every year. With only 3 classes of anti-fungal drugs available and a sharp increase in resistance seen in clinics, there is an urgent need for developing novel strategies against antifungal resistance. Read more

Investigating how large-scale genome instability in fungi contributes to the host-pathogen interactions.

Fungal infections affect billions of people, including >1.5 million global deaths each year. Our failure to achieve cure against fungal infections results from the high levels of tolerance and resistance to antifungal drugs in clinical fungal isolates. Read more

Fully funded studentships in Engineering Science for Health

The University of Surrey is seeking outstanding PhD candidates to undertake fully funded, 3.5 year studentships starting in October 2023. Read more

Reconstructing cis-regulatory networks underlying cell state transitions based on multiomics data, with applications to immunity and cancer

  Research Group: Functional Gene Control
Our lab employs a combination of advanced wet-lab and computational techniques to study how human cells make decisions to change their transcriptional state, with a particular emphasis on the role of DNA regulatory regions such as gene enhancers in this process. Read more

Assessing risks of resistance to novel antimicrobials targeting Pseudomonas aeruginosa

Commercial partner: . Bactobio Ltd. , London. Antibiotic resistance has emerged as an important threat to human health, and there is a clear need to develop new drugs that are active against multi-drug resistant bacterial pathogens. Read more

Power naps: ribosome hibernation as a booster of antimicrobial resistance

When bacteria are assaulted with drugs, they activate various defence mechanisms to stay alive and mitigate drug toxicity. These defence strategies allow pathogenic bacteria to escape clinical treatment, making drug-resistant infections a leading cause of death around the world. Read more

Understanding therapeutic resistance mechanisms in pancreatic cancer

Pancreatic cancer, or pancreatic ductal adenocarcinoma (PDAC), kills over 430,000 people every year. It is one of the deadliest epithelial malignancies, and both incidence and mortality are rising. Read more

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