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We have 75 drug design and development PhD Projects, Programmes & Scholarships

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drug design and development PhD Projects, Programmes & Scholarships

We have 75 drug design and development PhD Projects, Programmes & Scholarships

EPSRC Centre for Doctoral Training in Chemical Biology – Empowering UK BioTech Innovation

Applications to specific research projects are advertised on a rolling basis until the positions have been filled. Candidates will be interviewed by the project supervisors and the CDT directors. Read more

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Microneedle delivery systems for minimally-invasive patient diagnosis/monitoring

In this project, a novel type of integrated system will be investigated that will by-pass the skin barrier. On its surface will be multiple microscopic needles that pierce the skin without causing any pain – the sensation is said to feel like a cat’s tongue or sharkskin. Read more

Advanced Biosensors for dementia biomarker detection

Applications are invited for a PhD studentship to join the Advanced Biosensing group led by Dr Bing Li at the Institute for Materials Discovery (https://www.ucl.ac.uk/institute-for-materials-discovery/), University College London. Read more

Self-Immolative Polymeric Sensors

Stimuli-responsive compounds, such as self-immolative molecules and polymers,[1] have become significant targets in organic-based material development as systems of this type offer enormous potential in a diverse range of applications that span drug delivery, biological and chemical sensors, diagnostics, and degradable polymers or degrade-on-demand adhesives. Read more

PhD Project: 3D-Printed Micro-Robots for Medical Applications - (ENG 1726)

Applications are invited for a PhD project within the Faculty of Engineering, in the Centre for Additive Manufacturing research group (CfAM, http://www.nottingham.ac.uk/research/groups/cfam/index.aspx) at the University of Nottingham. Read more

Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

Viruses, these tiny but potent life forms, are all around us, infecting various organisms and directly affecting human health. Although in most cases, viral infection is not life threatening, in the minority of cases it leads to long-term disorders including cancer. Read more

Synthetic Protein-Transporters for Enhanced Transduction Activity

Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more

Integrated omics approach to psychiatric disorders

  Research Group: Chemistry and Biosciences
In psychiatry, the selection of antipsychotics and antidepressants is led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). Read more

Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more

Advancements in Finite Element Modeling of Soft Robotics for Biomedical Applications

This research project presents an intriguing opportunity for individuals intrigued by the intersection of finite element modeling and soft robotics, particularly within the realm of biomedical applications. Read more

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