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drug resistance PhD Projects, Programs & Scholarships

We have 55 drug resistance PhD Projects, Programs & Scholarships

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  Overcoming drug resistance in cancer using nano-encapsulated combination therapies
  Dr M Jones
Applications accepted all year round
Despite advances in cancer treatment, the development of drug resistance remains a major issue affecting long term patient survival.
  Targeting the Achilles’ heel – dissecting drug resistance in ovarian cancer
  Dr G Smith, Dr M Ferguson
Applications accepted all year round
Ovarian cancer, the most common cause of gynaecological cancer death, is frequently diagnosed when the disease is already advanced, when surgery is not always possible.
  Understanding the role of the globin cytoglobin in cancer cell drug resistance
  Dr N J Hodges
Applications accepted all year round
Cytoglobin is related to haemoglobin and myoglobin but has a very poorly understood biological function. Work in our lab has shown that expression of cytoglobin in cancer cells alters mitochondrial function and affords protection from anti-cancer drugs including cisplatin.
  Understanding drug-resistance in myeloid cancer
  Dr P Laslo
Applications accepted all year round
Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory.
  The role of tumour microenvironment interactions in melanoma therapy resistance
  Research Group: Institute of Cancer Therapeutics
  Dr H Sheldrake, Dr M Sutherland
Applications accepted all year round
The incidence of malignant melanoma has steadily increased over the past 30 years, and it is predicted that 76,250 new cases will be diagnosed in the US and over 10,000 in the UK this year.
  Gaining insight into the dynamics of drug-cancer cell interactions with the aid of continuous and hybrid multiscale models
  Dr M Cerasuolo, Dr J Foster, Dr A Burbanks
Application Deadline: 17 February 2019
Applications are invited for a fully-funded three year PhD to commence in October 2019. The PhD will be based in the School of Mathematics and Physics and will be supervised by Dr Marianna Cerasuolo, Dr Jamie Foster and Dr Andrew Burbanks.
  Exploration of 5-fluorouracil resistance mechanisms in colorectal cancer using 5-FU-resistant xenograft models
  Research Group: Institute of Cancer Therapeutics
  Dr S Shnyder, Dr C Sutton
Applications accepted all year round
Despite therapeutic advances, colorectal cancer (CRC) still has a 45% mortality rate, and one of the major problems is the development of acquired resistance to treatment with anticancer drugs.
  Nanotechnologies for cancer: developing new polymer-drug conjugates for the treatment of a range of cancers
  Dr F Greco, Prof H Osborn
Applications accepted all year round
Polymer anticancer-drug conjugates are drug delivery systems in which a low molecular weight anticancer agent is covalently conjugated to a water-soluble polymeric carrier.
  Tumour microenvironment and colorectal cancer development: understanding the mechanisms of the tumour growth
  Prof D Kerr, Dr S Cai
Application Deadline: 26 July 2019
Our group has conducted a series of international adjuvant trials of chemotherapy for colorectal cancer (Kerr RS. et al, (2016), Lancet Oncol, 17, 1543 – 1557).
  MRC DiMeN Doctoral Training Partnership: Addressing antimicrobial resistance (AMR): Affimers as therapeutic candidates and tools in antibacterial drug discovery
  Dr A O'Neill, Dr D Tomlinson
Application Deadline: 21 January 2019
The World Health Organization (WHO) has declared antimicrobial drug resistance (AMR) one of the greatest threats to human health, and it is predicted that this phenomenon will kill 10 million people annually by 2050 if not addressed.
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