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drugs design PhD Projects, Programs & Scholarships
We have 57 drugs design PhD Projects, Programs & Scholarships
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Precise, peptide-directed loading of drugs onto therapeutic antibodies for targeted imaging and treatment of tumors.
The PhD project aims to develop a non-covalent technology for loading small molecules and therapeutic enzymes onto monoclonal antibodies thus addressing issues in preparations of antibody-drug conjugates, such as poor yields and non-specific conjugation of the drugs resulting in compromised immunoaffinity. Read more
Investigation into the in-vitro lung deposition of liposomal formulations of the dual fixed-dose combination inhaler
Research Group:
Medicines Development and Pharmaceutical Sciences
Asthma and Chronic Obstructive Pulmonary Disease (COPD) are diseases associated with the airflow in the lungs (WHO, 2013). Inhalation is the most effective route of administration for treating asthma and COPD (Labiris and Dolovich, 2003). Read more
Computational Modelling of Bacterial Biofilm Permeability and the Design of Novel Antimicrobial Therapeutics
To evade the effects of antimicrobial drugs, such as antibiotics, colonies of bacteria embed themselves in a sticky extracellular matrix, called a biofilm. Read more
Structurally guided drug design on new antibiotics targeting DNA gyrase
Background. Antibiotic resistance is a huge problem in the field of antibacterial drugs, and much research is focused on the development of new drugs to overcome this. Read more
Formulation of poorly-soluble drugs
Poorly water-soluble drugs is an important class of pharmaceutical compounds that are finding numerous applications for the therapy of different pathological conditions. Read more
Last chance to apply
Preventing a chronic fibrotic response by designing smart implantable biomaterials
The University of Bath is inviting applications for the following PhD project commencing in October 2022 under the supervision of. Read more
Design, synthesis and evaluation of new integrin-targeting drugs
Research Group:
Institute of Cancer Therapeutics
The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more
Continuous Manufacturing of Amorphous Solid Dispersions using Hot Melt Extrusion based upon Quality by Design Principles: Understanding Critical Process Paramenters, Formulation Variables and Process Scale-up.
Orally administered drugs represent the most patient acceptable drug delivery platforms on the market offering high levels of patient acceptability and compliance. Read more
Design, synthesis and evaluation of next-generation nucleoside analogues
All viruses, irrespective of the disease they cause, have to replicate in order to survive. Drugs that block viral RNA or DNA replication by mimicking the natural building blocks of RNA and DNA (A, C, G, T/U) are known as nucleoside analogues. Read more
Towards the development of a novel class of broad-spectrum anti-infective drugs
Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more
Last chance to apply
Development of a novel controlled release anticancer drug delivery system using 3D printing
Make a real difference in cancer treatment. The . Centre for Cancer Diagnostics and Therapeutics. Read more
Machine Learning and Reaction Modelling: A Synergistic Approach to Rapid Reactivity Prediction
We have an exciting opportunity to work on the development of new synthesis prediction tools. Read more
Last chance to apply
Developing zeolite based anti-cancer drug delivery systems
The University of Bath is inviting applications for the following PhD project commencing in October 2022. The development and selection of materials for drug delivery systems is an important area of research for the pharmaceutical sector. Read more
Towards particle design of pharmaceutical crystals
This project is being pursued in collaboration with AstraZeneca and the successful applicant will be part of a larger research group supervised by Dr Cruz-Cabeza and Dr Ashwin Rajagopalan. Read more
Novel design of metallodrugs by mechanochemistry: towards a greener future
Research Group:
Chemistry and Biosciences
As a result of their important biological properties, metal complexes have been used in medicine for centuries. Read more
