University of Dundee
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dundee MRC PhD Projects, Programmes & Scholarships
We have 16 dundee MRC PhD Projects, Programmes & Scholarships
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Medical Research Council (MRC) Parkinson’s Disease and Neurodegeneration PhD Programme 2023
MRC Protein Phosphorylation and Ubiquitylation Unit (MRC PPU). University of Dundee, Scotland. Stipend £20,000 per annum tax-free. Read more
Medical Research Council (MRC) Chemical biology & Structural Biology PhD Programme 2023
MRC Protein Phosphorylation and Ubiquitylation Unit. University of Dundee, Scotland. Stipend £20,000 per annum tax-free. Read more
Medical Research Council (MRC) Cancer and Genome Integrity PhD Programme 2023
MRC Protein Phosphorylation and Ubiquitylation Unit. University of Dundee, Scotland. Stipend £20,000 per annum tax-free. Defects in DNA replication or DNA repair can lead to mutations and other genomic alterations that give rise to cancers, and consequently tumours tend to have a high degree of genome instability. Read more
Protein phosphorylation and ubiquitylation in cancer, infection and and neurodegenerative disease
MRC Prize PhD Programme 2023. MRC Protein Phosphorylation and Ubiquitylation Unit. University of Dundee, Scotland. Stipend £20,000 per annum tax-free. Read more
MSc by Research: Bringing proteins together with functional small molecules
Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more
Activation Mechanisms of Ubiquitin E3 ligases
E3 ligases are a startling class of enzyme that attach the small protein ubiquitin to substrates and regulate virtually all aspects of the cell. Read more
How does the TRAIP ubiquitin ligase guard the mammalian genome from damage?
The TRAIP ubiquitin ligase is a key regulator of genome integrity in mammalian cells. The importance of TRAIP is highlighted by the fact that mutation… Read more
Location, location, location: DNA damage sensors which launch protective responses to DNA damage
DNA damage happens at very high frequency in the cells in our bodies – meaning that the blueprint for the proper functioning of cells could be altered unless the mistakes are spotted and corrected. Read more
Rewiring cell signalling by targeted protein degradation and dephosphorylation
Post-translational modifications on proteins, such as reversible ubiquitylation and phosphorylation, are fundamental to controlling cellular signalling through regulation of protein stability and function. Read more
Finding the eat-me signals
The Ganley lab is interested in unravelling the molecular mechanism of autophagy (which literally translates from the Greek meaning to eat oneself). Read more
Protein Quality Control pathways at the endoplasmic reticulum
Around 30% of the proteome, including secretory proteins, plasma membrane proteins, and proteins targeted to organelles require the endoplasmic reticulum (ER) for their biosynthesis. Read more
Genome-wide screening approach to uncover novel regulators of organelle-selective autophagy
Autophagy was once thought to be a bulk, non-selective degradative pathway that cells employ during nutrient deprivation to rapidly break down cellular content for energy generation. Read more
Degrade or die
The Rousseau lab is interested in decoding how protein degradation by the proteasome is regulated in cells so that accumulation of unfolded, misfolded, or damaged proteins can be cleared before they become deleterious. Read more
The antiviral roles of ISG15 modifications
One of the most important challenges facing biomedical research is to understand the molecular details of how our immune system defends against pathogens. Read more
Molecular mechanisms underlying Parkinson's disease
There is great need for improved understanding of the mechanistic biology underlying Parkinson’s disease. Such knowledge will help with development of new drugs that slow or even halt the progression of the disease. Read more
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