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elegans PhD Projects, Programs & Scholarships

We have 11 elegans PhD Projects, Programs & Scholarships

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  Capturing how Hsp90 prevents the formation of cell-disruptive toxic amyloid species by Cryo-EM in a C. elegans model for Alzheimer’s Disease
  Research Group: BBSRC White Rose DTP
  Dr P van Oosten-Hawle, Prof N A Ranson, Dr E W Hewitt
Application Deadline: 7 January 2019
Stress and aging challenge the health of a proteome and increase susceptibility to protein conformational diseases, a hallmark of many neurodegenerative diseases, including Alzheimer’s Disease.
  MRC DiMeN Doctoral Training Partnership: Capturing how Hsp90 prevents the formation of cell-disruptive toxic amyloid species by Cryo-EM in a C. elegans model for Alzheimer’s Disease
  Prof N A Ranson, Dr P van Oosten-Hawle
Application Deadline: 21 January 2019
How and when do amyloid proteins cause cellular toxicity and disease? And how can we prevent their formation?. Using a C.
  MRC DiMeN Doctoral Training Partnership: Genetic epilepsy: identifying mechanisms and potential drug treatments, from nematodes to humans
  Prof A Morgan, Prof A Trevelyan, Dr A Ilie
Application Deadline: 21 January 2019
Epilepsy is a common neurological disorder that has a major impact on patient mortality, morbidity and quality of life. Clinical management remains extremely problematic, held back both by diagnostic and treatment limitations.
  MRC DiMeN Doctoral Training Partnership: Elucidating new redox-signalling mechanisms that act to maintain healthy tissues during ageing
  Prof E Veal, Prof M Jackson, Dr N Conlon
Application Deadline: 21 January 2019
Project Summary. This iCASE MRC studentship provides an exciting opportunity to use a diverse range of cutting-edge techniques, and exploit the advantages of different model systems, to identify new molecular mechanisms, that protect against ageing/age-associated diseases.
  How do cells generate functional asymmetries?
  Dr J Rodriguez
Application Deadline: 11 January 2019
The lab (https://www.staff.ncl.ac.uk/josana.rodriguez/) enjoys state of the art equipment and is situated in the ambitious and supportive research environment of the Institute for Cell and Molecular Biosciences (https://www.ncl.ac.uk/camb/), within the Medical School at Newcastle University (Newcastle upon Tyne, UK).
  MRC DiMeN Doctoral Training Partnership: Understanding asymmetric cell divisions at the onset of life
  Dr J Rodriguez, Prof M Herbert
Application Deadline: 21 January 2019
To generate a complex organism from a single-cell embryo, cells divide asymmetrically acquiring structural and functional differences.
  Building a nervous system: Analysis of transport and assembly mechanisms in synapse formation
  Dr M Kittelmann, Prof I Bermudez, Prof A McGregor
Application Deadline: 3 January 2019
In order for animals to react to an internal or external stimulus with the appropriate behaviour, the input signals need to be received, processes and transmitted correctly to the effector cells, e.g.
  Dissecting the role of DNA methylation in spiral cleavage
  Dr JM Martin, Dr R Lowe
Application Deadline: 31 January 2019
Nearly all animals originate during a process called embryogenesis, in which a single cell – the zygote – develops into a multicellular complex organism.
  Termination of DNA replication: mechanism and importance
  Dr A Gambus, Dr M Saponaro
Application Deadline: 6 January 2019
Cell division is the basis for the propagation of life and requires accurate duplication of all genetic information. DNA replication must be precisely regulated as unrepaired mistakes can change cell behaviour with potentially severe consequences, such as genetic disease, cancer and premature ageing.
  Complex network control of stem cell derived cultures
  Prof S Nasuto, Dr E Delivopoulos, Dr Y Hayashi
Applications accepted all year round
"In order to create a next generation of interfaces between prosthetic devices and the nervous system or to create next generation of intelligent robots – hybrids between artificial and biological systems, it is necessary to understand the principles that allow biological networks to achieve control of bodies.
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