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embryo PhD Projects, Programmes & Scholarships
We have 24 embryo PhD Projects, Programmes & Scholarships
Last chance to apply
Engineering an in vitro human embryo implantation platform to study pathologies arising in early pregnancy (S3.5-SMP-Lucas)
Embryo implantation is the step in early pregnancy where the founding tissue of the placenta from the embryo, called the trophoblast, establishes a physical connection with the mother at the inner lining of the uterus, called the endometrium. Read more
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Spatial-temporal markers of embryo viability for decision making in IVF
AI_CDT_DecisionMaking. Details. Infertility affects 1 in 7 couples leading to a rising demand for in vitro fertilisation (IVF) treatments. Read more
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The mechanics of early human development
This PhD project aims to delve into the complex mechanisms of mechanobiology and their crucial influence on human embryo development. Read more
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Developmental consequences of heat stress on pre-elongating and gastrulating pig embryos
Epidemiological evidence in humans and farm animals indicates that acute heat exposure around the time of mating results in pregnancy loss, with potential long-term consequences for offspring health, wellbeing and fertility. Read more
Sperm derived factors involved in egg activation.
At the fertilization in mammals the sperm initiates a series of Ca2+ oscillations by introducing PLCzeta into the egg. These Ca2+ oscillations activate embryo development. Read more
MSc by Research: Function of presomitic mesoderm specific phosphorylation of the Notch intracellular domain in somitogenesis
The Notch signalling pathway is one of the key pathways required for the developing embryo. It is especially important for the process of somitogenesis, the formation of body segments that develop into e.g. Read more
The role of planar cell polarity in developmental tissue fusion
Fusion of epithelial sheets during embryonic development is essential for all multicellular organisms, and maintaining subsequent epithelial integrity in organs throughout the life-course supports lifelong health. Read more
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BBSRC NWD: Identifying gene regulatory variants underlying vertebrate neural crest pathologies
Are you passionate about unravelling the mysteries of embryonic development and its impact on vertebrate evolutionary traits and pathologies? Apply for this PhD to explore the fascinating world of neural crest development and its role in vertebrate pathologies. Read more
Uncovering the mechanochemical signalling inputs that drive gastruloid axial patterning
How the early mammalian embryo converts a mass of identical cells in an organism with multiple axes of symmetry (anteroposterior, dorsoventral, mediolateral) is a critical question in developmental biology. Read more
Role of mechanosensing in the development of haematopoietic stem cells
Research Group:
Institute for Regeneration and Repair
Background. Haematopoietic stem cells (HSC) emerge from the endothelium of the embryonic dorsal aorta through the process called endothelial-to-haematopoietic transition (EHT). Read more
Investigating a polarity switch in bird wing feather development
The evolution of flight in birds is one of the most extraordinary events in natural history. A fundamental event was the formation of feathers, which first appeared in flightless ancestral theropod dinosaurs. Read more
Deciphering the role of biomechanical cues in embryonic cell fate decisions using human pluripotent stem cells
The structures that make up the human body trunk, such as the spinal cord and the vertebral column are produced during embryonic development by populations of stem cell-like progenitors (known as neuromesodermal progenitors or NMPs), which are located at the posterior of the embryo. Read more
MSc by Research: Investigation of the interplay between the cell cycle and Notch intracellular domain levels in presomitic mesoderm cells in somitogenesis
One of the key processes in embryo development is somitogenesis. This is the formation of segments, known as somites, that go on to develop into bone and skeletal muscle. Read more
Decoding mechanisms driving human germ cell development
In mammals, gamete formation ensures the transfer of genetic and epigenetic information to the next generation. Abnormalities in sperm and egg development can result in infertility and the formation of germ cell tumors. Read more
Does maternally restricted viral infection in pregnancy alter embryonic cytokine exposure and offspring fertility?
When a pathogen infects a cell, cellular sensors can alert the infected cell and its neighbours to the presence of an invader. When properly regulated, these responses lead to pathogen clearance and continued host health. Read more
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