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embryonic stem cells PhD Projects, Programs & Scholarships

We have 40 embryonic stem cells PhD Projects, Programs & Scholarships

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  Signalling pathways maintaining human embryonic stem cells
University of Manchester Faculty of Biology, Medicine and Health
  Prof S J Kimber, Prof D Brison
Applications accepted all year round
The aim of this project is to determine the function of novel genes predicted to have critical roles in preimplantation human development and in disease in later life.
Details
Type/Funding
  Innate antiviral immunity of human embryonic stem cells
University of Edinburgh School of Biological Sciences
  Research Group: Institute of Immunology & Infection Research
  Dr S Macias, Dr P De Sousa
Application Deadline: 13 December 2018
Unlike differentiated or somatic cells, embryonic stem cells (ESCs) are unable to activate their complete innate immune response when confronted with pathogens such as viruses.
Details
Type/Funding
  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
University of Birmingham Institute of Cancer and Genomic Sciences
  Dr S Sarkar
Applications accepted all year round
Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
Details
Type/Funding
  Mechanisms of poising at bivalent promoters and enhancers in embryonic stem cells
University of Edinburgh School of Biological Sciences
  Research Group: Institute of Cell Biology
  Dr P Voigt
Application Deadline: 13 December 2018
Histone modifications play key roles in the regulation of gene expression. In embryonic stem cells, promoters of developmental genes simultaneously carry histone H3 lysine 4 trimethylation (H3K4me3), which is usually found at active promoters, and H3K27me3, a hallmark of repressive chromatin.
Details
Type/Funding
  Investigating the molecular mechanisms of the MORF complex in chromatin
University of Edinburgh School of Biological Sciences
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr M Wilson, Dr P Voigt
Application Deadline: 13 December 2018
Histone modifications play key roles in the regulation of gene expression. In embryonic stem cells, promoters of developmental genes carry a signature combination of histone H3 lysine 4 trimethylation (H3K4me3), which is usually found at active promoters, and H3K27me3, a hallmark of repressive chromatin.
Details
Type/Funding
  4 Year Wellcome Triust PhD Programme: Investigating mRNA cap regulation in ES cells and T cells
University of Dundee School of Life Sciences
  Prof V Cowling
Application Deadline: 14 December 2018
IWe investigate the regulation and function of the mRNA cap, a modification of RNA essential for gene expression which integrates transcript processing and translation.
Details
Type/Funding
  Roles of histone acetylation in the control of bivalent genes during embryonic stem cell differentiation
University of Edinburgh School of Biological Sciences
  Research Group: Institute of Cell Biology
  Dr P Voigt, Dr A Kerr
Application Deadline: 13 December 2018
Histone modifications play key roles in the regulation of gene expression. In embryonic stem cells, promoters of developmental genes carry a signature combination of histone H3 lysine 4 trimethylation (H3K4me3), which is usually found at active promoters, and H3K27me3, a hallmark of repressive chromatin.
Details
Type/Funding
  Development of the hematopoietic/ immune system in the embryo: obtaining a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development
University of Oxford Radcliffe Department of Medicine
  Prof M DeBruijn
Application Deadline: 11 January 2019
Development of the hematopoietic/ immune system in the embryo. Our aim is to obtain a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development and determine the contribution of these cells to the emerging hematopoietic and immune systems of the embryo.
Details
Type/Funding
  MRC DTP 4 Year PhD Programme: mRNA cap regulation in embryonic stem cell function
University of Dundee School of Life Sciences
  Prof V Cowling, Dr M Stavridis
Application Deadline: 18 January 2019
This project is part of our exciting and challenging University of Dundee 4-year MRC DTP Programme in Quantitative and Interdisciplinary approaches to biomedical science.
Details
Type/Funding
  From Hematopoietic development towards generation of Hematopoietic stem cells
University of Edinburgh School of Biological Sciences
  Research Group: Institute of Stem Cell Research
  Prof A Medvinsky, Dr V Wilson
Application Deadline: 13 December 2018
Haematopoietic stem cells (HSCs) give rise to the majority of cells in the adult haematopoietic system, however, their embryonic development is poorly understood.
Details
Type/Funding
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