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We have 43 emerging disease PhD Projects, Programmes & Scholarships
emerging disease PhD Projects, Programmes & Scholarships
We have 43 emerging disease PhD Projects, Programmes & Scholarships
Unraveling the intersection of immune responses in gut and cardiovascular and health
Are you fascinated by the intricate workings of the immune system and its pivotal role in health and disease? Join our cutting-edge PhD project at the Kennedy Institute and delve into the dynamic interplay between immune responses, cardiovascular health, and inflammatory bowel diseases. Read more
Studies of brain renin angiotensin system changes in Parkinson’s disease to find new treatments
Parkinson’s disease (PD) is the second most common forms of neurodegenerative disease and affects people from the ages of 50years and above. Read more
Does the brain renin angiotensin system influence the occurrence of depression in Alzheimer’s disease?
In the last decade the involvement of imbalance in counterbalancing arms of the brain Renin Angiotensin System (RAS) has been found to be a significant factor in Alzheimer’s disease (AD). Read more
Investigating Gut-Immune Interactions in Parkinson’s Disease (PhD only)
It is now well established that both gastrointestinal dysfunction and immune activation occur in early Parkinson’s disease, and emerging evidence indicates that these processes are linked to faster disease progression. Read more
Investigating the Role of Subcortical Visual Pathways for 'Blindsight' and Gist Perception in Parkinson's Disease Using Multimodal Neuroimaging and Computational Neuroscience
Parkinson's disease (PD) is primarily known as a movement disorder, but emerging evidence suggests that it might also significantly impact visual processing, specifically 'blindsight' and gist perception (Diederich et al., 2014;Uchiyama st al., 2012). Read more
Extracellular vesicles in health and disease
Endothelial dysfunction (ED) is associated with classical and emerging risk factors of cardiovascular disease (CVD), correlates with disease progression and is an independent predictor of the risk of future cardiovascular events. Read more
Relationship between Tumour microenvironment and atherosclerotic cardiovascular disease during immunotherapy
Tumours actively escape the immune system by inducing an immunosuppressive state where intra-tumoural CD8 T-cells are “exhausted”, expressing an array of checkpoint inhibitory receptors, which results in a lack of effector functions. Read more
Unveiling Early Motor Neurone Disease Biomarkers: Insights from Neuromuscular Junction Dynamics
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that leads to the degeneration of motor neurons (MNs) in the brain and spinal cord. Read more
MSc by Research: ADP-ribosylation in dementia and motor neuron disease
ADP-ribosylation is a fundamental posttranslational modification where ADP-ribose is linked on to target proteins by ADP-ribose transferases and removed by the ADP-ribose hydrolases. Read more
Deconvoluting the spatial multi-omic landscape of high-grade glioma to target post-surgical residual disease
Background. High-grade gliomas are the most common cancers arising within the brain and contribute to ~190,000 brain tumour related deaths/year globally. Read more
Microplastics and Nanoplastics as Emerging Risk Factors in Neurodevelopmental and Neurodegenerative Condition
Project Overview. Microplastics (MPs) and nanoplastics (NPs) are ubiquitous environmental pollutants raising concerns due to their potential adverse effects on human health. Read more
Investigating cross-tissue and cross-disease immune mechanisms using single-cell/spatial multiomics & machine learning/AI-powered language learning tools
Immune cells play a fundamental role in health and disease. We are applying the latest molecular and cellular multi-omics analysis platforms (single-cell and spatial omics) and computational methods to deliver insights into immune cell biology across a range of human tissues (e.g. Read more
Neuroimmune regulation of rheumatoid arthritis
Rheumatoid arthritis (RA) is an immune mediated inflammatory disease which constitutes a major global healthcare challenge as it causes significant disability and pain. Read more
Urokinase-plasminogen activator as a target to block osteoarthritic cartilage destruction
Osteoarthritis (OA) is one of the major causes of disability globally, which is particularly significant in an ageing population. Read more
Defining the molecular mechanisms of leukaemia chemotherapies
Chemotherapies are usually the backbone of cancer treatment for either curative or palliative patient care. Multiple therapies can be used for the same disease, with the choice of drug dependent on parameters such as the patient’s age and fitness. Read more