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We have 44 emerging disease PhD Projects, Programmes & Scholarships

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emerging disease PhD Projects, Programmes & Scholarships

We have 44 emerging disease PhD Projects, Programmes & Scholarships

MScR: Probing the projections of different types of dopamine neurons

What makes one neuron different from another? How can we define different “types” of cells? Are cell types important?. In Parkinson’s disease some dopamine neurons seem to be more vulnerable to neurodegeneration. Read more

Examining the dysfunction of DNA damage repair in synucleinopathies

DNA damage is an emerging stressor implicated in the pathogenesis of neurodegenerative diseases. Our recent research within post-mortem dementia with Lewy body brain tissue has highlighted the dysregulation of several DNA damage repair pathways, alongside the occurrence of a novel nuclear alpha-synuclein pathology. Read more

Exploring Molecular Pathways for Improved Neural Regeneration in Spinal Cord Injury

In the UK, 50,000 people currently live with spinal cord injury (SCI), and an additional 2,500 new cases are reported annually. SCI results in a permanent loss of sensation and movement, serving as a primary cause of paralysis for which effective treatments are currently unavailable. Read more

Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

Intracellular Capillarity of Biomolecular Condensates

The emerging role of biomolecular condensates formed through a liquid-liquid phase separation process inside biological cells is driving a paradigm change in our understanding of cellular organisation. Read more

Common genetic origins of visual and neurocognitive disorders

There is emerging evidence that apparently distinct neurodegenerative diseases have common genetic origins. For example, genes such as ARMS2 and HTRA1, which are fundamental to regulating neuronal health, are implicated in both dementia and diseases of the retina (particularly age-related macular degeneration). Read more

PhD Studentship in Artificial Cell Engineering and Bioinspired Technologies

PhD Studentships in Artificial Cell Engineering and Bioinspired Technologies. The Elani Group in the Department of Chemical Engineering at Imperial College London welcomes applications for a PhD studentship to conduct work in the area of Artificial Cell Engineering and Bioinspired Technologies. Read more

New strategies to cryopreserve cell-based therapies

In the past decade, cell-based therapies have emerged to transform the treatment of disease, particularly cancer. Whilst potent, these therapies are challenging to deliver in practise as must be stored frozen (cryopreserved). Read more

Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks

The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children. Read more

Fractional order modelling of neurons

Project Overview. Fractional order calculus (integro-differential equations that are of non-integral order) is an emerging methodology with wide applications across all areas of Physics and Engineering. Read more

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