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enzyme PhD Projects, Programmes & Scholarships
We have 59 enzyme PhD Projects, Programmes & Scholarships
York YBDTP project: Understanding nickel homeostasis for improved industrial enzyme production
Lead supervisor: Prof G H Thomas. Co-supervisors: Prof Alison Parkin (Chemistry). Industrial partner. HydRegen Ltd. The student will be registered with the Department of Biology (University of York). Read more
CASE Project: Understanding nickel homeostasis for improved industrial enzyme production
This project will be undertaken in collaboration with HydRegen Ltd and will involve a minimum 3-month placement based at the Industry Partner's premises. Read more
Last chance to apply
De-novo palladium-containing enzymes
Background. This project will be carried out in collaboration with Johnson-Matthey. Metalloenzymes are critical for catalyzing a wide range of biochemical transformations, including biomass degradation. Read more
Wearable Sample Collection for Biosensing
Measurement of low abundance proteins is key for enabling early detection of diseases [1]. A widely used method for the measurement of low abundance proteins is enzyme-linked immunosorbent assay (ELISA) [2]. Read more
Exploring enzyme-mediated degradation of plant biomass by in situ imaging for biosecurity
It is estimated by the food and agriculture organisation that the global loss of crops is between 20-40%, costing over $220 billion in losses. Read more
Wall Teichoic Acid biosynthesis inhibitors to fight antibiotic resistance
Background and aims. Antibiotic resistance is a growing threat to human health. In 2019, more than 1.2 million people died globally as a result of antimicrobial resistant bacterial infections; of these, more than 100,000 deaths were attributed to methicillin-resistant Staphylococcus aureus (MRSA). Read more
Catalytic nanocages for in situ drug delivery
Therapeutic nanoreactors are innovative nanocompartments that confine one or more biocatalysts (e.g., enzymes) for the in-situ production of therapeutic agents, enabling targeted drug delivery with minimal off-site toxicity. Read more
Molecular mechanisms underpinning A. baumannii virulence
. Antimicrobial resistance (AMR) is a major public health threat. Acinetobacter baumannii, is the leading cause of nosocomial infections worldwide, where its high resistance to antibiotic treatments and ability to cause lethal infections, has led to its categorisation as a “critical priority” pathogen by the WHO1. Read more
York YBDTP project: Broadening the Catalytic Promiscuity of Amide Bond Synthetases using Directed Evolution and Robotic Screening
Lead supervisor: Prof Gideon Grogan . Co-supervisors: Prof Ian Fairlamb. The student will be registered with the Department of Chemistry (University of York). Read more
York YBDTP project: Broadening the Catalytic Promiscuity of Amide Bond Synthetases using Directed Evolution and Robotic Screening
Lead supervisor: Prof Gideon Grogan . Co-supervisors: Prof Ian Fairlamb. The student will be registered with the Department of Chemistry (University of York). Read more
Broadening the Catalytic Promiscuity of Amide Bond Synthetases using Directed Evolution and Robotic Screening
The industrial production of pharmaceutical compounds requires that they are synthesised in a very specific way, and that the methods used, where possible, involve non-toxic materials and the least hazardous conditions. Read more
Engineering Biocatalysis: Unleashing the Potential of Hyper-Thermostable Phosphorylated-Sugar Nucleotide Metabolising Enzymes
Thermostable enzymes have attracted much attention as they benefit from many advantages. Read more
Dynamics of metabolically-active biomolecular condensates
Membraneless organelles are functional subcellular structures that have been receiving increasing interest and attention in the biosciences community. Read more
Comprehensive investigation of the impact of proglucagon gene and GIP gene products on metabolic control
Research Group:
Biomedical Sciences
New and highly effective drugs for the treatment of obesity and diabetes, such as liraglutide (Victoza®, Saxenda®), semaglutide (Ozempic®, Wegovy®) and tirzepatide (Mounjaro®, Zepbound®) are essentially derived from products of the proglucagon and GIP genes. Read more
[FSE Bicentenary PhD] Bioremediation through enzymatic dehalogenation
The production of organohalides is fundamental to a variety of industrial applications, including their use as solvents, degreasing agents, pesticides, and flame retardants. Read more