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enzyme PhD Projects, Programmes & Scholarships

We have 67 enzyme PhD Projects, Programmes & Scholarships

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We have 67 enzyme PhD Projects, Programmes & Scholarships

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Engineering Enzymes for Organic Synthesis

Engineering Enzymes for Organic Synthesis. Professor Gideon Grogan, Department of Chemistry, University of York. Background. Our research group is interested in the identification and characterisation of enzymes and their application to organic synthesis. Read more

Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more

Development of antiviral peptidomimetic enzyme inhibitors against SARS-CoV-2

Coronaviruses are a large group of viruses that circulate and evolve among various animals. They can cause mild human illnesses such as the common cold or more serious respiratory diseases as seen in the recent outbreaks of SARS (2002), MERS (2012), and the COVID-19 pandemic (2019). Read more

Enzyme dynamics, design and evolution

A PhD studentship are available to begin in 2022 as part of PREDACTED (. https://cordis.europa.eu/project/id/101021207. ), a European Research Council project based at University of Bristol. Read more

A step change in the modelling of enzymatic catalysis

A deep understanding of enzymatic processes requires an atomic-level description, which is often beyond experimental techniques but achievable through synergy with computational chemistry. Read more

Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more

A ’sweet’ new strategy for tackling superbugs: using chemical enzymology for the discovery and inhibition of glycosyl transferases in multi-drug resistant bacteria

A PhD position is available in the lab of Dr Martin Fascione and Prof Gavin Thomas to work on an ERC Consolidator Grant funded chemical glycobiology project focussed on the discovery and inhibition of novel glycosyl transferase enzymes active on rare pseudaminic acid sugars (1, 2, 3) present on bacterial surfaces. Read more

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