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enzymology PhD Projects, Programmes & Scholarships

We have 24 enzymology PhD Projects, Programmes & Scholarships

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We have 24 enzymology PhD Projects, Programmes & Scholarships

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A ’sweet’ new strategy for tackling superbugs: using chemical enzymology for the characterisation and inhibition of carbohydrate active enzymes in multi-drug resistant bacteria

A PhD position is available in the lab of Dr Martin Fascione and Prof Gavin Thomas to work on an ERC Consolidator Grant funded chemical glycobiology project focussed on the discovery and inhibition of novel glycosyl transferase enzymes active on rare pseudaminic acid sugars (1, 2, 3) present on bacterial surfaces. Read more
Last chance to apply

EASTBIO Disrupting bacterial biofilms with peptide-coated hydrogels

  Research Group: Biomedical Sciences Research Centre
BACKGROUND. Biofouling is the accumulation of microorganisms in a surface, ultimately causing degradation and decay. If devices are in contact with water and moisture it will occur to ships, medical devices, and several instruments employed in manufacturing. Read more

Investigating the mechanism of mucin degradation by a key member of the human gut microbiota

The human gut microbiota is closely associated with health, development and disease. The thick mucus layer in the colon is the key barrier between the contents of the lumen and the epithelial cells, providing protection against potential pathogens and environmental insults. Read more
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Identification and mechanistic understanding of enzymes optimised for high pH detergent environments

Northumbria and Newcastle Universities are collaborating with Procter & Gamble (P&G) to identify new, sustainable ways of improving detergency and breakdown of dirt on clothes under challenging conditions. Read more

MRC DiMeN Doctoral Training Partnership: Characterising Human Milk Oligosaccharides in Breast Milk and their Degradation by Bifidobacterium species.

This project in collaboration with industrial partners at ThermoFisher Scientific will combine modern molecular microbiology techniques including anaerobic culturing, with protein biochemistry and carbohydrate structural analysis for a complete analysis of human milk (HMO) oligosaccharides degrading apparatus of Bifidobacterium strains and HMO profiling in breast milk samples. Read more
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EASTBIO Probing the mechanism and dynamics of Staphylococcus aureus m1A22-tRNA methyltransferase

  Research Group: Biomedical Sciences Research Centre
S. aureus has been a leading cause of healthcare- and community-associated infections worldwide, with a number of patients infected with methicillin-resistant S. Read more
Last chance to apply

EASTBIO Identifying, characterising and engineering plant cell wall degrading enzymes for biofuel production

  Research Group: Biomedical Sciences Research Centre
The effects of climate change have never been more apparent, which demands an urgent need for cleaner and greener processes for energy production. Read more

Molecular level understanding of Mycobacterium tuberculosis

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

Elucidating and exploiting molecular mechanisms of bacterial natural product biosynthesis

  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
Natural product-based therapeutics are an essential part of modern medicine, and are also used widely in agriculture, e.g. as fungicides. Read more

Life imitates art (or design, at least): Understanding a new group of membrane proteins

A PhD studentship is available to investigate the structure and function of a novel group of integral membrane proteins. This is a collaborative project between the laboratories of Dr Paul Curnow and Professor Ross Anderson in the School of Biochemistry at the University of Bristol. Read more

Using new Fourier transform voltammetry methods to map electron transfer in bio-hydrogen producing enzymes

Background. The EU target of net zero greenhouse gas emissions by 2050 will only be met by developing new energy technologies, including methods to synthesise fuel molecules as a stable and transportable store of seasonal solar and wind energy. Read more
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Blending Synthetic Biology and Synthetic Chemistry for Catalytic C-H Activation and Diversification

This PhD Studentship Provides the Opportunity to Blend Synthetic Chemistry with Synthetic Biology. The project is linked to our pioneering and multi- award winning work in using enzymatic C-Cl/C-Br/C-I bond formation in complement with synthetic technologies for precision molecule editing. Read more

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