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enzymology PhD Projects, Programmes & Scholarships
We have 11 enzymology PhD Projects, Programmes & Scholarships
Developing novel light-induced in-situ Electron Paramagnetic Resonance (EPR) methods
Light-induced in-situ Electron Paramagnetic Resonance (EPR) studies are a growing field in both continuous wave and pulsed EPR. It can be used to monitor photoactivated chemical and biochemical reactions involving radical reagents, projects or intermediates. Read more
Molecular Silencing of Epithelial Sodium Channel (ENaC) using a Peptide Technology to Deliver Treatment for Cystic Fibrosis
Cystic fibrosis (CF) is an autosomal recessive disease characterized by a progressive decline in lung function and tissue damage associated with mucus obstruction of the airways, impaired clearance mechanisms and chronic cycles of inflammation and infection. Read more
Defining how aldehydes regulate human metabolism
Second Supervisor. Peter Harvey, School of Chemistry & Sir Peter Mansfield Imaging Centre – School of Medicine, University of Nottingham. Read more
CSC studentship: Understanding human sulfatases involved in heparan sulfate degradation
Various types of carbohydrates, or sugars, are ubiquitous throughout nature and perform a number of important functions in our cells. Read more
CSC studentship: Protein engineering for new C-nucleoside production
Nucleosides are essential components of DNA, RNA, and other molecules that are vital for cell function. Therefore, nucleoside analogues have long been employed as drugs to combat cancer, viral infections, and microbial diseases. Read more
The sweet side of ‘evil twin’ sugars: using chemical glycobiology tools to explore the role bacterial sialic acids play in host immune evasion by pathogens
Sugars, or glycans as they are more commonly known, are the most abundant biomolecules on earth and play essential roles in a myriad of biological processes including energy storage, cell-cell recognition and the immunological response. Read more
Human milk oligosaccharides and the infant gut microbiota
Species of Bifidobacterium dominate the infant large intestine and they use human milk oligosaccharides as their source of nutrition. Read more
MRC DiMeN Doctoral Training Partnership: Uncovering the molecular mechanisms underpinning A. baumannii virulence
Outline. Antimicrobial resistance (AMR) is a major public health threat. Acinetobacter baumannii, is the leading cause of nosocomial infections worldwide, where its high resistance to antibiotic treatment and ability to cause lethal infections, has led to its categorisation as a “critical priority” pathogen by the WHO1. Read more
Biocatalytic Synthesis and Degradation of Organosilicon Compounds
In synthetic chemistry, there has been increasing prominence in the use of engineered enzymes to execute chemical transformations. Read more
Molecular level understanding of Mycobacterium tuberculosis
Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more
Optimising the delivery of light into Electron Paramagnetic Resonance samples
Electron Paramagnetic Resonance (EPR) is a magnetic resonance method that can be used to study any systems containing unpaired electrons. Read more
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