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enzymology PhD Projects, Programs & Scholarships

We have 15 enzymology PhD Projects, Programs & Scholarships

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We have 15 enzymology PhD Projects, Programs & Scholarships

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Making Light Work With Bacterial Nanowires (BUTT_U22DTPR)

Inspired by natural photosynthesis and addressing limitations of purely synthetic approaches, this PhD project aims to provide proof of principle for light-driven chemical synthesis through the design and assembly of novel inorganic:biological hybrid materials. Read more

Evolution and engineering of non-ribosomal peptide synthetases (WILKINSON_J22DTP1)

The discovery & development of penicillin sparked ‘The Golden Age of Antibiotics’ which spanned the 1940’s to 1960’s when most major classes of antibiotics were discovered. Read more

Genome mining of novel antimicrobial and antiviral natural products from new bacterial strains

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses. Read more

EASTBIO Bacterial selfishness, and how bacterial communities cope with nutrient shortage

  Research Group: Biomedical Sciences Research Centre
BACKGROUND. Most antibiotics target rapidly dividing bacteria. However, for the majority of their existence, bacteria grow in conditions where a few or most nutrients are limiting so that very little to no propagation takes place. Read more

Understanding human sulfatases involved in heparan sulfate degradation

  Research Group: Biomedical Sciences Research Centre
Various types of carbohydrates, or sugars, are ubiquitous throughout nature and perform a number of important functions in our cells. Read more

(BBSRC DTP CASE) Towards a photocatalytic carboxylase

Illumination is able to unlock a wide range of photochemical reactions, but light is rarely used by living organisms. In fact, to date only three light dependent enzymes have been described in detail. Read more

Biochemical pathology of diabetes: Mechanisms of cysteine depletion during hyperglycaemia (HAMILTONC_U22SF)

In humans, the cysteine-containing tripeptide glutathione (GSH) is an essential thiol cofactor that maintains an intracellular reducing environment to protect against oxidative stress, which causes lipid, protein & DNA damage. Read more

Unravelling the structure and conformational dynamics of membrane proteins using H/D-exchange mass spectrometry and cryo-EM

A dynamic studentship which includes experience working in both academic and pharmaceutical industry environments. the project is performed in partnership between laboratories at both King’s College London and UCB Pharma (Slough, 20 miles West of Central London). Read more
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