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We have 34 epigenetic PhD Projects, Programmes & Scholarships

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epigenetic PhD Projects, Programmes & Scholarships

We have 34 epigenetic PhD Projects, Programmes & Scholarships

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Decoding drug resistance mechanisms in acute myeloid leukaemia

  Research Group: The Patrick G Johnston Centre for Cancer Research
Acute myeloid leukaemia (AML) is an aggressive blood cancer with survival rates below 25% at five years. Despite initial treatment success, many patients relapse due to the persistence of drug-resistant cancer cell populations. Read more
 Supervisor: Dr SM Maguire
 14 April 2025  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Epigenetic Regulation of Antifungal Resistance in the Human Fungal Pathogen, Aspergillus fumigatus

The global impact of human fungal pathogens is huge but underappreciated. More than 300 million individuals are affected by serious fungal infections, and around 3.8 million people die from fungal diseases every year. Read more
 Supervisor: Dr TF Furukawa
 31 March 2025  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MSc by Research: Defying Mendel’s laws: developing tools to understand the principles of epigenetic inheritance in tomato plants

In plants, phenotypic innovation is not exclusively encoded in DNA sequences. Some heritable new traits are associated with modifications on the DNA, such as DNA methylation. Read more
 Supervisor: Dr C Martinho
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Decoding the epigenetic mechanisms of drug resistance in aggressive breast cancers

Breast cancers pose a major health burden to modern world as being the most common cancer in women. Estrogen receptor (ER), the classical marker of 70% these cancers, is the nuclear receptor important for cancer progression. Read more
 Supervisors: Dr S Nagarajan, Prof R Clarke, Prof A Sharrocks
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating Epigenetic and Epitranscriptomic regulation in Acute Myeloid Leukemia (AML)

Epigenetic and epitranscriptomic changes constitute pivotal factors driving the development and progression of various human cancers, including leukemia. Read more
 Supervisors: Prof Y Shi, Prof S Constantinescu
 8 April 2025  PhD Research Project  Funded PhD Project (Students Worldwide)
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Detecting epitranscriptomic signatures in circulating cell-free RNA for early cancer detection

Although recent advances in cancer research offer new ways to treat cancer, early detection still represents the best opportunity for curing cancer. Read more
 Supervisor: Prof C Song
 8 April 2025  PhD Research Project  Funded PhD Project (Students Worldwide)
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Age-related disease: Fidelity mechanisms that protect against epigenetic decay

Inside the mammalian cell nucleus DNA and associated proteins are spatially organised and differentially compacted, so that some genes are accessible and some are not. Read more
 Supervisors: Prof D Coverley, Dr A Mason
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Epigenetic control of alternative promoter utilisation

Many human genes are regulated through alternative promoter utilisation, some examples of which can be induced by experiment, and many of which occur in diseases such as cancer. Read more
 Supervisor: Prof G Tucker-Kellogg
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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CRUK Black Leaders in Cancer Non-Clinical PhD Scholarship: Deciphering the expression of regulatory noncoding RNAs specific to metastasis in breast cancers

This programme is aimed at students from Black heritage backgrounds pursuing a PhD in cancer-related fields. This scheme is open to people who self-identify as being from a Black heritage background, including a mixed background, for example. Read more
 Supervisors: Dr S Nagarajan, Prof A Sharrocks, Prof R Clarke, Prof D Wedge, Prof C Kirwan
 4 April 2025  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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125th Anniversary Scholarships for Black British Researchers - How does the environment shape (epi)genome plasticity in long-lived plants?

Scientific motivation. The ability of a genome to change, also known as genome plasticity, is a key factor for diversification and evolution. Read more
 Supervisors: Dr E Luna-Diez, Dr M Catoni
 30 April 2025  PhD Research Project  Funded PhD Project (UK Students Only)
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Model-based Design and Analysis of Artificial Bacterial Memory Systems

PHD RESEARCHER POSITION (f/m/d, 75%, 13 TV-L, fixed-term contract for up to 4 years). MODEL-BASED DESIGN AND ANALYSIS OF ARTIFICIAL BACTERIAL MEMORY SYSTEMS. Read more
 Supervisor: Prof N Radde
 11 April 2025  PhD Research Project  Funded PhD Project (Students Worldwide)
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Early detection of cancer from cell-free DNA

Earlier detection of cancer by minimally invasive diagnostic tests could substantially reduce cancer mortality. One analyte that holds enormous promise as a cancer biomarker is cell-free DNA (cfDNA). Read more
 Supervisor: Dr B Schuster-Boeckler
 8 April 2025  PhD Research Project  Funded PhD Project (Students Worldwide)
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Gene Regulation in Brain Development and Disease – Funded PhD at the University of Exeter. Ref: 5496

Supervisors. Primary supervisor: Dr Sean Flynn . Secondary Supervisor: Professor Jonathan Mill . Project Summary. Read more
 Supervisors: Dr S Flynn, Prof J MIll
 18 April 2025  PhD Research Project  Funded PhD Project (UK Students Only)
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The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more
 Supervisors: Dr R Hager, Dr M Harte, Dr J Glazier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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On-therapy monitoring of oesophageal cancer and recurrence detection: the Blood-based LIquid Sequencing Study (BLISS)

Oesophageal cancer is undergoing a therapeutic revolution, with first-generation immunotherapy trial results reading out in the next 12 months, and second-generation bispecific agents beginning evaluation alongside new targeted agents for Claudin 18.2, Her2, and FGFR. Read more
 Supervisors: Dr R Owen , Dr B Schuster-Boeckler
 8 April 2025  PhD Research Project  Funded PhD Project (Students Worldwide)

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