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epigenetic PhD Projects, Programs & Scholarships

We have 94 epigenetic PhD Projects, Programs & Scholarships

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  Epigenetic control of transgenerational genome plasticity
  Dr M Catoni
Application Deadline: 6 January 2019
Epigenetics is the major discipline studying heritable changes of gene activity that do not involve changes in the underlying DNA sequence.
  The role of recruiting epigenetic regulators by the LMO2 complex in making cell fate choices
  Dr M Hoogenkamp
Application Deadline: 6 January 2019
The three germ layers give rise to the approximate 200 different cell types found in mouse and man. The cardiovascular system, including the blood, is derived from the mesoderm.
  The role of the epigenetic diet in modulating apoptotic cell death in human carcinogenesis (ref: SF18/APP/Panagiotidis)
  Prof M Panagiotidis
Applications accepted all year round
Epigenetic modifications can contribute to carcinogenesis by various means including altering gene expression responsible for evading apoptotic cell death, abnormal cell proliferation, etc.
  Profiling stem cell epigenetic transitions within the Drosophila hematopoietic stem cell niche
  Dr P Badenhorst, Prof C Bonifer
Applications accepted all year round
The self-renewal and differentiation of stem cells is controlled by signals derived from the microenvironment or “niche”. The paired hematopoietic organs of the Drosophila genetic model organism are a well-characterized system in which the regulation of stem cell behaviour within a niche can be genetically dissected.
  Pinpointing genetic and epigenetic influences on adiposity
  Research Group: MRC Human Genetics Unit
  Prof C Haley
Application Deadline: 18 January 2019
This is one of several projects available on an MRC funded 4-year multi-disciplinary PhD programme in Human Genetics, Genomics and Disease at the MRC Human Genetics Unit (HGU), part of the Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh.
  MRC Precision Medicine DTP: Using machine learning to dissect genetic effects on DNA methylation heterogeneity in cancer
  Research Group: MRC Human Genetics Unit
  Dr D Sproul:, Dr G Sanguinetti
Application Deadline: 7 January 2019
Background. Genetic and epigenetic heterogeneity are fundamental hallmarks of cancer. Advances in high-throughput sequencing have resulted in the extensive characterisation of intra-tumoural genetic heterogeneity.
  Epigenetic mechanisms in CD5+ malignant B lymphocytes
  Research Group: Centre for Experimental Medicine
  Dr E Kostareli, Prof K Mills
Application Deadline: 20 January 2019
B-cell receptor (BCR) signalling is a complex molecular network critical for normal B-cell development and function. Among the numerous proteins of BCR pathway, Bruton tyrosine kinase (BTK) has gained significant attention over the last decade.
  Epitranscriptomic mechanisms in the maternal to zygotic transition of vertebrate embryos
  Research Group: BBSRC MIBTP
  Dr M Soller, Prof F Mueller
Applications accepted all year round
Most mRNAs contain modified nucleotides in mRNA, but we know very little about their function (Haussmann et al, 2016, Dezi et al, 2016, Roignant and Soller, 2017).
  PhD project on Epigenetic Mechanisms in Neuroscience: uncovering the role of three dimensional chromatin organization
  Dr E Elliott
Applications accepted all year round
We are seeking an enthusiastic student for a novel project on the epigenetic basis of behavior. The goal of the project, under the direct supervision of Dr.
  DNA Strategic Epigenetic Biomarkers in Melanoma
  Dr C Proby, Prof C N A Palmer
Applications accepted all year round
Hypothesis. That tumour-specific DNA methylation present in free circulating DNA from melanoma patients will enable early detection of disease relapse or metastasis facilitating life-preserving benefit from additional therapies such as immune checkpoint inhibitors.
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