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We have 20 epilepsy PhD Projects, Programmes & Scholarships

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epilepsy PhD Projects, Programmes & Scholarships

We have 20 epilepsy PhD Projects, Programmes & Scholarships

Epilepsy and the ageing brain

Our ability to remember ‘where I put my car keys today’ instead of ‘where I put them yesterday’ depends on a computational process called pattern separation. Read more

Using microRNA inhibitors to boost GABAergic inhibition as a genetic therapy for epilepsy

Epilepsy is a chronic neurological disease characterised by recurrent spontaneous seizures and cognitive co-morbidities. Current small molecule approaches to treating epilepsy are ineffective in a significant portion of cases, and are associated with substantial adverse effects. Read more

Development of a toolkit to improve prescribing appropriateness for children with epilepsy

3 Year Funded PhD open to UK/Home applicants only. Starting September 2024. Background.  Adherence to medication in children and young people (CYP) with epilepsy measured by objective assessment is estimated to be 58%(1) with non-adherence to medication closely associated with poorer seizure outcomes.(2). Read more

The breakdown of neurovascular coupling in the diseased state specifically Epilepsy and Alzheimer’s disease

Epilepsy is the most common neurological condition in the UK, affecting 1 – 2 % of the population. Epilepsies often involve only a small area of the brain - the epileptic focus – and the abnormal activity can propagate out from there. Read more

The impact of seizures and antiseizure medications on the cognitive performance of adult rodents.

People with epilepsy frequently suffer cognitive comorbidities which impact greatly on quality of life. The UK Epilepsy Research Institute has funded a Doctoral Training Centre in North-West England focused on research into cognition in people with epilepsy and their offspring. Read more

Investigation into the antiepileptic efficacy and mechanism of combination vitamin D and Ganoderma Lucidum polysaccharides

Epilepsy, caused by abnormal firing of neurons in the brain, affects 50 million people globally [1]. Almost one-third of epileptic patients do not respond well to antiepileptic drugs, and their side effects are associated with cognitive impairment, psychiatric problems, and recurrent epileptic adverse reactions [2, 3]. Read more

Anomaly detection for pathology diagnosis by using EEG

Electroencephalograph (EEG) is an economical and convenient auxiliary diagnosis tool for many neurological diseases (e.g., stroke, epilepsy, depression etc.), In recent years, machine learning has shown great potential in clinical EEG anomaly detection. Read more

In silico modelling of endocannabinoid evolution

In the brain, the endocannabinoid (eCB) system maintains adequate neurotransmission (Lu and Mackie 2016). Indeed, the eCB system provides a negative feedback mechanism, preventing over-activation of synaptic transmission. Read more

Self funded MSc by Research or PhD in Biology: Ion channel signalling in cancer cells

Lead supervisor: Dr W Brackenbury. The student will be registered with the Department of Biology. Our cells constantly sense and transport ions present in their environment. Read more

Developing a clinical pathway to support nurse led whole genome sequencing for neurological diseases

In this project we will develop pathways to enable specialist nurses to request whole genome sequencing (WGS) for adult neurology patients throughout the NHS; improving the efficiency of the process, freeing consultant neurologist time and improving equity of access. Read more

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