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fibrosis PhD Projects, Programmes & Scholarships
We have 30 fibrosis PhD Projects, Programmes & Scholarships
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Fully funded PhD studentship - Misprogramming of mesenchymal progenitor cells in human lung fibrosis
Faculty of Medicine. Main Supervisor. Dr Mark Jones. Other members of the supervisory team. Prof Donna Davies, Dr Yihua Wang, Dr Rob Ewing. Read more
Adverse myocardial remodelling in cardiac fibrosis and atrial fibrillation
Our main focus is to understand the mechanisms of two major often linked heart conditions cardiac fibrosis and atrial fibrillation. Read more
Inter- and intra-cellular signalling in the development of fibrosis in the hypertensive heart
Project Overview. Heart failure is a leading cause of morbidity and mortality worldwide. In terms of volume, the normal heart is composed mostly of terminally-differentiated contractile cells (cardiomyocytes), responsible for the pump action of the heart. Read more
The effect of cocaine and benzoylecgonine (BZE) on morphological microstructural changes of cardiac tissues: Implications for cardiac fibrosis
Cocaine is the second most widely used illicit drug in the UK and the number of deaths involving cocaine was at an all-time high in 2015. Read more
Evaluation of the therapeutic potential of pharmacological NRF2 activation in hepatic fibrosis
This project is one of 17 four year PhD Studentships funded by Medical Research Scotland (. https://www.medicalresearchscotland.org.uk. Read more
Targeting molecular mechanisms of fibrosis to develop new therapies.
Fibrosis is a common endpoint of chronic inflammatory disease and is therefore implicated in >40% of deaths in the developed world. Read more
Macrophage-bacteria interactions in Cystic Fibrosis: The Cellular microbiology of the novel opportunistic bacterium achromobacter species
Chronic infection and persistent inflammation in people with cystic fibrosis (PWCF) lead to progressive lung damage. Read more
Modelling scar formation in endometriosis
This opportunity will remain open until the position has been filled and so early applications are encouraged. Endometriosis affects 10-15% of women during their reproductive years and is often associated with debilitating pelvic pain and impaired fertility. Read more
Palliative care needs of patients with Idiopathic Pulmonary Fibrosis (IPF) and Lung Cancer in North Lancashire and South Cumbria
This exciting funded PhD project, supervised by experienced clinical academics is based at Lancaster University and will research health services in North Lancashire and South Cumbria. Read more
A multidisciplinary approach to model and reveal the mechanisms of fibrotic tissue formation follow injury
Working in Partnership with industry. To apply for this programme, please visit. www.advanced-biomedical-materials-cdt.manchester.ac.uk. Read more
A Multi-Omics approach to understanding cardiovascular risk in patients with End-Stage Kidney Disease
Background. End-stage Kidney failure, also known as End-Stage Kidney Disease (ESKD), is the final, irreversible stage of chronic kidney disease (CKD), where kidney function has worsened to the point that the kidneys can no longer function independently. Read more
Exploiting the protein O-Glycosylation pathway in opportunistic bacteria as an novel antimicrobial target
The problem. Antibiotic resistance has become a global health problem of epidemic proportions, especially for infections caused by Gram-negative bacteria. Read more
Development of novel small molecule inhibitors of Gremlin1, a pathogenic driver of diabetic kidney disease
Gremlin1 is a secreted protein antagonist of bone morphogenetic proteins (BMPs) that regulated developmental processes such as limb and kidney formation. Read more
The respiratory microbiome as a tool to predict exacerbations of disease
The Respiratory Microbiome Group welcomes applications from self-funded PhD students year round. Read more
A ’sweet’ new strategy for tackling superbugs: using chemical enzymology for the discovery and inhibition of glycosyl transferases in multi-drug resistant bacteria
A PhD position is available in the lab of Dr Martin Fascione and Prof Gavin Thomas to work on an ERC Consolidator Grant funded chemical glycobiology project focussed on the discovery and inhibition of novel glycosyl transferase enzymes active on rare pseudaminic acid sugars (1, 2, 3) present on bacterial surfaces. Read more
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