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fibrosis PhD Projects, Programs & Scholarships

We have 55 fibrosis PhD Projects, Programs & Scholarships

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  MRC Precision Medicine DTP: Defining Therapeutic Targets for Human Liver Fibrosis using Single-cell Transcriptomics
  Research Group: MRC Centre for Inflammation Research
  Dr P Ramachandran, Prof N Henderson, Prof T Freeman
Application Deadline: 7 January 2019
Background. Chronic liver disease is estimated to affect 844 million people worldwide, with over 2 million deaths per year. Liver fibrosis (or scarring) is a feature of advanced chronic liver disease of any aetiology and predicts adverse patient outcomes.
  The role of modified microRNAs in fibrosis during ageing
  Dr K Whysall, Prof G Bou-Gharios
Application Deadline: 22 November 2019
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate the expression of multiple mRNAs posttranscriptionally (Brown & Goljanek-Whysall, Aging Res Rev 2015).
  Molecular mechanisms controlling cardiac fibroblast proliferation during cardiac fibrosis
  Dr M Bond
Applications accepted all year round
Applicants are invited for a new self-funded PhD studentship to study the molecular mechanisms of cardiac fibrosis. Myocardial fibrosis is a significant global health problem associated with nearly all forms of heart disease.
  MRC DiMeN Doctoral Training Partnership: Role of primary cilium in morphogen signalling modulation by Transforming Growth Factor-beta (TGF-beta) and its involvement in tissue fibrosis and aberrant wound healing
  Dr F Del Galdo, Dr N.A. Riobo-Del Galdo
Application Deadline: 21 January 2019
We offer an exciting opportunity to investigate the molecular basis underlying tissue fibrosis, at the epigenetic, molecular and cellular level.
  Connective Tissue Fibrosis: Understanding basic biological mechanisms and the development of targeted therapies
  Prof G Bou-Gharios
Applications accepted all year round
The PhD proposal is aimed at understanding some of the fundamental mechanism(s) that control extracellular matrix (ECM) proteins and to develop new technologies and therapeutic based on changes in fibroblast gene expression profiling and surface antibodies during the development of connective tissue fibrosis.
  Characterisation of human lung tissue for mechanisms of fibrosis and evaluating novel treatments/fibrosis reversal strategies.
  Dr L Smyth
Applications accepted all year round
This project uses primary human lung tissue sourced via informed consent from patients receiving clinical care in the NHS for lung disease.
  Myocardial biology with a specific focus on the mechanisms underlying cardiac fibrosis and atrial fibrillation
  Dr S Reilly, Assoc Prof M Lei
Application Deadline: 11 January 2019
Using a combination of extensive cell culture and molecular biology techniques, and functional cellular assays to understand molecular mechanisms underlying myocardial structural and electrical remodelling associated with atrial fibrillation.
  (BBSCR DTP) Design of allosteric small molecule probes of fibrosis using molecular dynamics simulations
  Dr R A Bryce, Dr K Piper Hanley, Dr R Whitehead
Application Deadline: 31 January 2019
Integrins are a family of protein receptors that play a major role in cell survival, growth and migration. Their function is to transmit signals across the cell membrane by undergoing an elegant large scale structural rearrangement.
  Translational Lung Immunology: Studying the contribution of the immune system to lung injury, repair and fibrosis
  Dr L Ho, Dr L Denny
Application Deadline: 11 January 2019
We work on the mechanisms of lung injury, repair and fibrosis, with a particular focus on how monocytes and macrophages influence these processes.
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