The Nano-Immunology group is based in the Human Immunology Unit at the MRC WIMM. The Group is headed by Prof Christian Eggeling, an expert in fluorescence microscopy and especially in the development and application of super-resolution fluorescence (STED) microscopy with a long-standing record in this field.
DNA-modifying enzymes are becoming increasingly important in genetic medicine. The development and effective use of gene-based therapies demands the specific and sensitive detection of the activities of these enzymes.
Project co-supervised with Dr D. Cherny. Pre-mRNA splicing is highly complex. Over a hundred proteins and several RNA species assemble into dynamic complexes, in a pathway defined by several stable partial complexes.
Supervisory Team. Dr Corinne Whitby ([email protected]) - School of Biological Sciences, University of Essex. Dr Philippe Laissue ([email protected]) – School of Biological Sciences, University of Essex.