Our lab are interested in cell signalling via small G proteins of the Ras superfamily. We use a range of biochemical, biophysical and structural approaches to understand these fascinating proteins, which are involved in multiple cellular processes and are often deregulated in diseases such as cancer.
The Arctic Ocean is undergoing rapid environmental change. The Arctic is warming twice as fast as the global average. The areal extent of sea ice has declined by 9% per decade since 1978 (Comiso 2012).
In crisis management (e.g. from fire and rescue to accidents management), operators tend to rely on a number of different types of data and artefacts to deliver sensemaking of crises and prompt decision-making for recovery.
Using a combination of extensive cell culture and molecular biology techniques, and functional cellular assays to understand molecular mechanisms underlying myocardial structural and electrical remodelling associated with atrial fibrillation.