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gene PhD Projects, Programs & Scholarships

We have 359 gene PhD Projects, Programs & Scholarships

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Showing 1 to 10 of 359
  Development of Gene Therapy and Gene Editing for Lung Disorders: the translation of new gene therapies to the clinic, including the development of new vectors, and evaluation in animal models of disease.
University of Oxford Radcliffe Department of Medicine
  Dr D Gill, Dr S Hyde
Application Deadline: 26 July 2019
The Gene Medicine Research Group is based in the John Radcliffe Hospital and is focused on the development of new gene therapeutics for lung diesases.
Details
Type/Funding
  Airway, Liver and Muscle Gene Transfer to Create Therapeutic Protein Factories: utilising experience of in vivo gene transfer and/or in vivo gene editing to understand and manipulate the factors required for effective expression and secretion of therapeutic proteins
University of Oxford Radcliffe Department of Medicine
  Dr S Hyde, Dr D Gill
Application Deadline: 26 July 2019
We are focusing on strategies to deliver therapeutics via in vivo delivery of gene transfer vectors to generate ectopic “protein factories” capable of secreting therapeutic proteins into both the lung lumen and the systemic circulation.
Details
Type/Funding
  Gene Regulatory Networks in Development and Disease: Focusing on systems level “big picture” approaches to understand gene regulation and build gene regulatory networks during development and disease in zebrafish, chick, lamprey and human models.
University of Oxford Radcliffe Department of Medicine
  Dr T Sauka-Spengler
Application Deadline: 26 July 2019
Focusing on systems level “big picture” approaches to understand gene regulation and build gene regulatory networks during development and disease in zebrafish, chick, lamprey and human models.
Details
Type/Funding
  Gene Regulation: How mammalian genes are switched on and off during development and differentiation and how this goes awry in human genetic diseases
University of Oxford Radcliffe Department of Medicine
  Prof D Higgs, Assoc Prof J Hughes, Dr R Gibbons, Dr V Buckle
Application Deadline: 26 July 2019
Other Potential Supervisors. Mira Kassouf. Our laboratory addresses the question of how mammalian genes are switched on and off during development, lineage commitment and differentiation.
Details
Type/Funding
  (BBSRC DTP) Partitioning primary and secondary changes of gene expression caused by gene mutations
University of Manchester Faculty of Biology, Medicine and Health
  Dr D Talavera, Prof G D Pavitt, Dr J-M Schwartz
Application Deadline: 31 January 2019
Control of gene expression is a complex cell process, which involves balancing both the synthesis and the degradation of RNA and protein so as to establish optimal levels of each protein.
Details
Type/Funding
  Development of gene therapies for muscular dystrophies
Royal Holloway, University of London School of Biological Sciences
  Dr L Popplewell
Applications accepted all year round
The activities in the Popplewell lab focus on the development of pre-clinical gene therapies for neuromuscular diseases, in particular muscular dystrophies based on gene replacement, endonuclease-mediated gene editing, antisense oligonucleotide (AO)-induced exon skipping and gene sliencing.
Details
Type/Funding
  (BBSRC DTP) Probing Regulatory Networks setting Notch signalling levels in vivo in Drosophila and Zebrafish.
University of Manchester Faculty of Biology, Medicine and Health
  Dr M Baron, Dr S Herbert, Prof S Hubbard
Application Deadline: 31 January 2019
Development of organisms and maintenance of healthy tissues depends on proper control of cell to cell communication networks that control cell fate and behaviour.
Details
Type/Funding
  PhD In Psychological Medicine & Clinical Neurosciences - The impact of FAN1 on gene editing approaches for Huntington’s disease
Cardiff University Cardiff School of Medicine
  Prof V Dion, Prof A L Jones, Dr T Massey
Application Deadline: 27 February 2019
Huntington’s disease (HD) is an autosomal dominant disease that leads to neurodegeneration and death inexorably within 15 to 20 years.
Details
Type/Funding
  Functional coronary artery disease genetics: investigating the role of the candidate gene in models of In vivo cardiovascular disease
University of Oxford Radcliffe Department of Medicine
  Dr G Douglas, Prof K Channon
Application Deadline: 26 July 2019
Despite significant advancements in its treatment coronary artery disease is the leading cause of death in both the UK and world wide, accounting for over 66,000 deaths in the UK each year.
Details
Type/Funding
  PhD in Psychological Medicine & Clinical Neurosciences - Analysing the mechanisms underlying dystonia pathogenesis through characterisation of a Drosophila melanogaster model of Myoclonus Dystonia
Cardiff University Cardiff School of Medicine
  Dr K Peall, Dr O Peters
Application Deadline: 27 February 2019
ackground. Dystonia is one of the most common movement disorders, affecting ~1% of the population worldwide. Well recognised forms include writer’s cramp, although more severe forms are frequently observed.
Details
Type/Funding
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