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gene PhD Projects, Programs & Scholarships

We have 238 gene PhD Projects, Programs & Scholarships

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  Partitioning primary and secondary changes of gene expression caused by gene mutations
  Dr D Talavera, Prof G D Pavitt, Dr J-M Schwartz
Applications accepted all year round

Funding Type

PhD Type

Control of gene expression is a complex cell process, which involves balancing both the synthesis and the degradation of RNA and protein so as to establish optimal levels of each protein.
  Development of gene therapies for muscular dystrophies
  Dr L Popplewell
Applications accepted all year round

Funding Type

PhD Type

The activities in the Popplewell lab focus on the development of pre-clinical gene therapies for neuromuscular diseases, in particular muscular dystrophies based on gene replacement, endonuclease-mediated gene editing, antisense oligonucleotide (AO)-induced exon skipping and gene sliencing.
  Identification of colistin resistant gene, mcr-1, in clinical isolated Enterobacteriaceae and characterisation of pathogenicity and virulence of mcr-1 harboured bacterial pathogens
  Research Group: Chemistry and Biosciences
  Dr C Chang, Dr J N Fletcher
Applications accepted all year round

Funding Type

PhD Type

Globally, infectious disease accounts for more than 13 million deaths a year and is one of the main causes of death around the world, predominantly in developing countries.
  The genomics of sperm killing gene drive
  Dr T Price, Prof G Hurst, Prof S Paterson
Applications accepted all year round

Funding Type

PhD Type

Many selfish genetic elements spread rapidly through populations by killing gametes that do not carry them. This fascinating phenomena also has practical applications.
  Novel anti-inflammatory mechanisms of cyclic-AMP in vascular smooth muscle cells
  Dr M Bond
Applications accepted all year round

Funding Type

PhD Type

A self-funded PhD studentship is available at the University of Bristol to study novel anti-inflammatory mechanisms of cyclic-AMP in vascular disease.
  Development of treatment for Osteoarthritis by blocking metalloproteinases
  Prof G Bou-Gharios
Applications accepted all year round

Funding Type

PhD Type

MMP13 (collagenase 3) plays a vital role in the pathogenesis of osteoarthritis (OA) because MMP13 preferentially cleaves type II collagen, the main component of cartilage, and both MMP13 levels and enzymatic activity are enhanced in OA.
  Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression
  Dr D Blažek, Assoc Prof Z Zdráhal, Dr P Alexiou
Application Deadline: 31 October 2019

Funding Type

PhD Type

CDK11 is ubiquitously expressed in all tissues and the CDK11 null mouse is lethal at an early stage of development indicating an important role for Cdk11 in the adult as well as during development.
  Synthetic Virology: Development of gene delivery vectors/synthetic vaccines
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

There is worldwide interest in exploiting our modern understanding of genomics to target gene expression therapeutically via a variety of mechanisms, such as transgene insertion and CRISPR-Cas gene editing.
  Gene Regulation by the KAT6A/MOZ Histone Acetyltransferase
  Prof D Heery
Applications accepted all year round

Funding Type

PhD Type

The human KAT6A and KAT6B genes encode the nuclear proteins MOZ and MORF, which are key gene regulators in development of blood, brain and other tissues.
  Watching the Hippo pathway in real time in growing organs
  Dr K. Harvey
Applications accepted all year round

Funding Type

PhD Type

A new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Traditionally, researchers have drawn conclusions about gene function using indirect techniques that only allow us to infer what a gene normally does, without actually watching it work.
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