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We have 284 gene PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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gene PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 284 gene PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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Interrogating molecular switches that control developmental gene expression

The ability of cells and tissues to modulate rates of gene expression is critical for their ability to respond appropriately to cues during development, maintain normal function during ageing, and combat environmental insults and biological agents such as pathogens. Read more

Understanding the gene regulatory landscape of embryonic stem cells and cancer cells

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity. Read more

SynBac: Synthetic Baculovirus Genomes for Next-generation Drug Discovery and Gene Therapy

Baculovirus is a highly efficient delivery system for recombinant genes into eukaryotic cells, with great impact on the production of eukaryotic proteins, including high-value drug targets for pharmaceutical development. Read more

Combining Synthetic Biology and Modelling to Understand and Predict Evolution

Mutations, and their effects on organismal fitness, lie at the heart of understanding and predicting evolution. Because of its central role in determining evolutionary outcomes, much experimental and theoretical effort has been put into describing the fitness effects of mutations. Read more

Antimicrobial resistance and gene regulation in Enteroaggregative Escherichia coli.

Enteroaggregative Escherichia coli (EAEC) is a major cause of diarrhoeal disease in industrialized and non-industrialized countries and has been shown to be the cause of travellers’ diarrhoea and persistent diarrhoea in children and HIV patients. Read more

Mechanistic analysis of neurodevelopmental disorders caused by mutations in the gene RAC1

RAC1 is a signalling protein that regulates many cellular processes and is essential during embryonic development. We recently discovered a novel genetic disease called RAC1-related neurodevelopmental disorder (RAC1-NDD) that results from mutations in the RAC1 gene. Read more

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