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gene delivery PhD Projects, Programs & Scholarships

We have 18 gene delivery PhD Projects, Programs & Scholarships

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  Mechanistic Study of Molecular Assembly for Drug and Gene Delivery
University of Sheffield Department of Chemical & Biological Engineering
  Dr X Zhao
Applications accepted all year round
Despite numerous advances over the past several decades, effective drug and gene delivery with high efficiency, low toxicity and cell targeting remains challenging.
Details
Type/Funding
  Development of Gene Therapy and Gene Editing for Lung Disorders: the translation of new gene therapies to the clinic, including the development of new vectors, and evaluation in animal models of disease.
University of Oxford Radcliffe Department of Medicine
  Dr D Gill, Dr S Hyde
Application Deadline: 26 July 2019
The Gene Medicine Research Group is based in the John Radcliffe Hospital and is focused on the development of new gene therapeutics for lung diesases.
Details
Type/Funding
  Magnetic-silk Core-shell Nanoparticles for Targeted Drug and Gene Delivery
University of Sheffield Department of Chemical & Biological Engineering
  Dr X Zhao
Applications accepted all year round
Silk is a protein fibre produced by silkworm. It has been used for centuries because of its unique properties.
Details
Type/Funding
  Airway, Liver and Muscle Gene Transfer to Create Therapeutic Protein Factories: utilising experience of in vivo gene transfer and/or in vivo gene editing to understand and manipulate the factors required for effective expression and secretion of therapeutic proteins
University of Oxford Radcliffe Department of Medicine
  Dr S Hyde, Dr D Gill
Application Deadline: 26 July 2019
We are focusing on strategies to deliver therapeutics via in vivo delivery of gene transfer vectors to generate ectopic “protein factories” capable of secreting therapeutic proteins into both the lung lumen and the systemic circulation.
Details
Type/Funding
  Peptide Self-assembling for Biomedical Applications
University of Sheffield Department of Chemical & Biological Engineering
  Dr X Zhao
Applications accepted all year round
Designed short peptides can self-assemble into different nanostructures (such as nanovesicles and nanofibrils) through weak interactions and have a variety of applications.
Details
Type/Funding
  NIR Light-triggered delivery of viral vectors for gene therapies
University of Manchester School of Materials
  Dr S Jones
Applications accepted all year round
This project looks to develop a platform technology that utilises external stimuli, such as light for the triggered polymer un-coating of viral vectors for in-vivo targeted delivery.
Details
Type/Funding
  Vascular-targeted gene therapy to block proliferation of smooth muscle cells using a novel adenovirus vector
University of Edinburgh College of Medicine and Veterinary Medicine
  Prof A Baker, Dr D E Newby
Application Deadline: 1 April 2019
Many strategies have emerged to improve the function of the blood vessel wall following acute injury, including targeting endothelial cell function, vascular smooth muscle cell proliferation and migration and adventitial progenitor cells.
Details
Type/Funding
  First steps towards gene therapy for congenital bladder disease
University of Manchester Faculty of Biology, Medicine and Health
  Dr N Roberts, Prof A Woolf
Applications accepted all year round
In the congenital disease urofacial syndrome (UFS), urinary bladder voiding is incomplete due to poor co-ordination between detrusor muscle contraction and bladder outlet relaxation.
Details
Type/Funding
  Dual-Action Anti-Cancer Drug Delivery Vehicles
University of York Department of Chemistry
  Prof D K Smith
Applications accepted all year round
Cancer is a challenging disease target, and requires wide-ranging strategies for intervention. Given the difficulties in treating recalcitrant tumours, multi-mode therapies are of significant potential value.
Details
Type/Funding
  Genome Engineering and Synthetic Biology: Design and implementation of synthetic circuits for research and therapeutic applications.
University of Oxford Radcliffe Department of Medicine
  Prof T Fulga
Application Deadline: 26 July 2019
Design and implementation of synthetic circuits for research and therapeutic applications.
Details
Type/Funding
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