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gene delivery PhD Projects, Programs & Scholarships

We have 24 gene delivery PhD Projects, Programs & Scholarships

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  Mechanistic Study of Molecular Assembly for Drug and Gene Delivery
  Dr X Zhao
Application Deadline: 23 January 2019
Despite numerous advances over the past several decades, effective drug and gene delivery with high efficiency, low toxicity and cell targeting remains challenging.
  Development of Gene Therapy and Gene Editing for Lung Disorders: the translation of new gene therapies to the clinic, including the development of new vectors, and evaluation in animal models of disease.
  Dr D Gill, Dr S Hyde
Application Deadline: 11 January 2019
The Gene Medicine Research Group is based in the John Radcliffe Hospital and is focused on the development of new gene therapeutics for lung diesases.
  Magnetic-silk Core-shell Nanoparticles for Targeted Drug and Gene Delivery
  Dr X Zhao
Application Deadline: 23 January 2019
Silk is a protein fibre produced by silkworm. It has been used for centuries because of its unique properties.
  Airway, Liver and Muscle Gene Transfer to Create Therapeutic Protein Factories: utilising experience of in vivo gene transfer and/or in vivo gene editing to understand and manipulate the factors required for effective expression and secretion of therapeutic proteins
  Dr S Hyde, Dr D Gill
Application Deadline: 11 January 2019
We are focusing on strategies to deliver therapeutics via in vivo delivery of gene transfer vectors to generate ectopic “protein factories” capable of secreting therapeutic proteins into both the lung lumen and the systemic circulation.
  Regulation of arterial remodelling by Wnt proteins as result of hypertension
  Prof S George, Dr J Johnson
Applications accepted all year round
Sustained hypertension is a major risk factor in cardiovascular disease, playing a significant role in atherosclerosis and kidney insufficiency.
  Resurrecting ancestral human sugars: a novel ‘molecular archaeology’ approach to cancer immunotherapy using chemical bioconjugation
  Dr M A Fascione, Prof G Davies, Prof J Southgate
Application Deadline: 9 January 2019
Background. Human cells surfaces are coated in a thick layer of sticky sugars called the glycocalyx. The composition of this coating is dynamic and changes depending on cell type and function.
  Peptide Self-assembling for Biomedical Applications
  Dr X Zhao
Application Deadline: 23 January 2019
Designed short peptides can self-assemble into different nanostructures (such as nanovesicles and nanofibrils) through weak interactions and have a variety of applications.
  NIR Light-triggered delivery of viral vectors for gene therapies
  Dr S Jones
Applications accepted all year round
This project looks to develop a platform technology that utilises external stimuli, such as light for the triggered polymer un-coating of viral vectors for in-vivo targeted delivery.
  First steps towards gene therapy for congenital bladder disease
  Dr N Roberts, Prof A Woolf
Applications accepted all year round
In the congenital disease urofacial syndrome (UFS), urinary bladder voiding is incomplete due to poor co-ordination between detrusor muscle contraction and bladder outlet relaxation.
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