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We have 146 gene expression PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
gene expression PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 146 gene expression PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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Partitioning primary and secondary changes of gene expression caused by gene mutations
Control of gene expression is a complex cell process, which involves balancing both the synthesis and the degradation of RNA and protein so as to establish optimal levels of each protein. Read more
Exploring how cancer cells transmit force into the nucleus to regulate gene expression
Overview. This project will explore the mechanobiology of skin cancer cells and seeks to understand the mechanisms by which force is transmitted from the tumour microenvironment into the nucleus. Read more
Understanding regulation of gene expression during development via an integrated computational analysis of ‘omics data
Embryonic development requires exquisite control of the expression of large numbers of genes, integrating components from the genome, transcriptome and proteome. Read more
MSc by Research: Is control of gene expression at the translational level important for limb development?
Ribosomes are core components of all cells required for the translation of mRNA into protein. Read more
Interrogating molecular switches that control developmental gene expression
The ability of cells and tissues to modulate rates of gene expression is critical for their ability to respond appropriately to cues during development, maintain normal function during ageing, and combat environmental insults and biological agents such as pathogens. Read more
Development and validation of a radiosensitivity gene expression signature in prostate cancer
Prostate cancer (PCa) is diagnosed in 1.4 million men globally each year and causes 375,000 deaths, making PCa the second most common cancer and fifth most common cause of death from cancer in men[1]. Read more
Cell signalling and gene expression dynamics in Drosophila
During Drosophila development, cell signalling and gene expression are regulated in space and time to allow the correct cell fate decisions. Read more
Using single cell transcriptomic and blood proteomic data to understand how pancreatic cancer causes diabetes and to find ways to detect the cancer earlier.
Background. Pancreatic cancer is the deadliest of the common cancers. Five-year survival remains low at 10%. Sadly for 80% of patients, by the time their cancer is diagnosed it has spread to distant organs making them ineligible for potentially curative surgery. Read more
Roles of negative transcriptional regulators in cancer cells
The aim of the project is to investigate how factors involved in mRNA synthesis alter gene expression in human cells. Precise control of transcription and RNA processing is essential for the correct regulation of gene expression in all eukaryotic organisms. Read more
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(MRC DTP CASE) Development of deep learning methods and software to infer pathway enrichment from histology images - application to liver fibrosis
Histopathological images are routinely used to characterize complex phenotypes. For example, pathologists regularly study stained images of tissue biopsies for cancer diagnosis as cancer is known to change the morphological features of cells including cell shape and size [1]. Read more
Development of deep learning methods and software to infer pathway enrichment from histology images - application to liver fibrosis
Histopathological images are routinely used to characterize complex phenotypes. For example, pathologists regularly study stained images of tissue biopsies for cancer diagnosis as cancer is known to change the morphological features of cells including cell shape and size [1]. Read more
MSc by Research: The role of 5’-UTRs in temperature-regulated gene expression
Plants display a remarkable degree of developmental plasticity, tailoring their growth and shape to their environment. Read more
THE HARD FACTS ABOUT VASCULAR INFLAMMAGING: Role of vascular stiffness on vascular smooth muscle cell inflammatory phenotype
ABSTRACT. Chronic inflammation is a major factor in the initiation and progression of many cardiovascular pathologies, including atherosclerosis, abdominal aortic aneurysms, and pulmonary artery hypertension. Read more
Haustoria-omics with proteomics, transcriptomics, and gene silencing, to understand fungal pathogenicity and plant resistance during powdery mildew disease in food crops
Powdery mildews (PMs) are prevalent plant diseases that compromise the production of many valuable food and horticultural crops, including cereals, strawberry, cucurbits and pea. Read more
Transcriptional control of vascular development
Sprouting of new capillaries from pre-existing vessels (angiogenesis) promotes the formation of almost all blood vessels during development, growth and tissue regeneration. Read more