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gene therapy PhD Projects, Programmes & Scholarships
We have 39 gene therapy PhD Projects, Programmes & Scholarships
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4-year PhD Studentship: Apolipoprotein E-targeted stem cell gene therapy for people with Alzheimer’s disease
Alzheimer’s disease (AD) is a devastating progressive neurological disease, and a major increasing global health challenge. Read more
Self funded BMS Project: Understanding the population dynamics of haematopoietic stem cells during gene therapy for sickle cell disease
Applications accepted for PhD Only. Background. This project builds on the recent discovery that whole genome sequencing approaches in blood stem and progenitor cells can be used to estimate the number of actively contributing blood stem cells in humans (Lee-Six et al., Nature 2018). Read more
4-year PhD Studentship: Nanoparticle Gene Therapy for Autosomal Dominant Polycystic Kidney Disease
Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent Mendelian inherited kidney disease (prevalence 1/1000). Read more
Apolipoprotein E-targeted stem cell gene therapy for people with Alzheimer’s disease
Perros Trust-supported 1 Year Full MSc R Scholarship for students of Black or Mixed Black Heritage backgrounds. Project Description. Read more
Development and use of advanced optical microscopy to facilitate gene delivery and gene therapy in 3D cardiac disease models
This is an exciting fully funded PhD studentship opportunity exploring the pathogenesis and treatment of human cardiac diseases with a potential for a vast array of 3D tissue engineering applications using advanced optical microscopy techniques. Read more
Producing a mobility outcome measure for use in clinical trials for eye disease
When testing new treatments in clinical trials, using the right outcome measures can be critical in the success or failure of the trial. Read more
Gene correlation network showing differences in gene expression of effector T cells derived from the bone marrow or peripheral tissues affected by GVHD.
Our group is interested in developing novel immunotherapeutic approaches for leukaemia. Clinical approaches currently used include allogeneic haematopoietic stem cell transplantation, chimeric antigen receptor T cell therapy and immune checkpoint inhibitors. Read more
Gene correlation network showing differences in gene expression of effector T cells derived from the bone marrow or peripheral tissues affected by GVHD.
Our group is interested in developing novel immunotherapeutic approaches for leukaemia. Clinical approaches currently used include allogeneic haematopoietic stem cell transplantation, chimeric antigen receptor T cell therapy and immune checkpoint inhibitors. Read more
Protein degradation-based gene therapies for neurodegenerative disease
Proteins fold like origami into complex three-dimensional shapes. This process can malfunction and result in misfolded proteins that stick together to form large aggregates. Read more
Runx1 and Heart Failure
Project outline: . Coronary heart disease (CHD) leading to myocardial ischaemia is the predominant cause of heart failure (HF) and premature mortality in the UK. Read more
4-year PhD Studentship: Investigating PZ-128 as a novel treatment for nephrotic syndrome and diabetic nephropathy
Idiopathic Nephrotic Syndrome (INS) is a devastating disease in children that is typically associated with oedema, proteinuria, hypertension, microscopic haematuria, and renal insufficiency and usually leads to end stage renal failure despite the use of prolonged and toxic immunosuppression. Read more
Self funded BMS Project: Therapeutic potential of extracellular vesicles from different mesenchymal stem cell subtypes.
Human mesenchymal stem/stromal cells (MSCs) are found in adult tissues such as bone marrow and are able to differentiate into bone, cartilage and fat tissues. Read more
EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture
Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more
RNA Interference for Glioblastoma therapy using lipid nanoparticles
University of Central Lancashire Funded Doctoral Training Centre for Industry Collaboration. Inaugural PhD Studentships. The successful applicant will receive an annual stipend payment of £16062 and tuition fees will be covered. Read more
Elucidating the intrinsic role of PD-L1 in 3D immuno-oncology breast cancer models
A number of immunotherapies are currently approved for the treatment of cancer patients, with several of these aimed at inhibiting Programmed Death Ligand-1 (PD-L1). Read more