gene expression PhD Projects, Programmes & Scholarships

Fully funded PhD position on using genomics to inform climate smart resilience breeding in the marine finfish snapper (tāmure/Chrysophrys auratus)

New Zealand Institute for Plant & Food Research Limited Seafood Genomics

Project description. Climate change is increasingly impacting food production systems and industry needs to better prepare for future climate challenges. Read more

Supervisors: Prof M Wellenreuther, Dr A Santure

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Delineating the IRF6 regulatory network driving periderm formation and function

The University of Manchester Faculty of Biology, Medicine and Health

During development, the ectoderm passes through a series of cell states to produce a self-replenishing, multi-layered epidermis. Initial stratification forms a single-cell layer of flattened periderm cells which act as a barrier to prevent pathological adhesions during embryogenesis. Read more

Supervisors: Prof M Dixon, Dr J Dixon

Year round applications PhD Research Project Self-Funded PhD Students Only

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SLS SF1: Investigating the basis of invasive multi-drug resistant Salmonella Dublin

University of Westminster School of Life Sciences

Salmonella Dublin belongs to non-typhoidal Salmonella that primarily causes self-limiting gastrointestinal illness in humans; however, it has adapted to cause invasive disease and life-threatening infections, especially in elderly people, children, and immunocompromised individuals. Read more

Supervisors: Dr MM Mohammed , Dr J Murphy, Dr MAC Chattaway

17 May 2024 PhD Research Project Self-Funded PhD Students Only

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Exploring Molecular Pathways for Improved Neural Regeneration in Spinal Cord Injury

University of Portsmouth School of Pharmacy and Biomedical Sciences

In the UK, 50,000 people currently live with spinal cord injury (SCI), and an additional 2,500 new cases are reported annually. SCI results in a permanent loss of sensation and movement, serving as a primary cause of paralysis for which effective treatments are currently unavailable. Read more

Supervisors: Dr J Cayuso, Dr P Dey, Prof A Butt

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanisms of the increase in maximal aerobic capacity (VO2max) with regular exercise

University of Stirling Faculty of Health Sciences and Sport

Research Group: PENRG - Physiology Exercise and Nutrition Research Group

Performing regular exercise is crucial for good health and wellbeing, whereas failing to perform sufficient exercise increases the risk of diseases such as cardiovascular disease, type 2 diabetes, cancer, etc. Read more

Supervisors: Dr N Vollaard, Dr ECR Hall

Year round applications PhD Research Project Self-Funded PhD Students Only

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Helminth products as macrophage “trainers”: a novel tool to induce anti-inflammatory trained immunity

Kingston University Faculty of Health, Science, Social Care and Education

The innate immune system can display characteristics of immunological memory. This phenomenon, termed “trained immunity”, refers to the long-term functional reprogramming of innate immune cells after the encounter with infectious or non-infectious agents that influences their capacity to respond to a secondary stimulus. Read more

Supervisor: Dr N Garrido Mesa

Year round applications PhD Research Project Self-Funded PhD Students Only

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Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

University of Bristol Bristol Medical School

Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 T-cell responses. Read more

Supervisor: Dr P Maghsoudlou

Year round applications PhD Research Project Self-Funded PhD Students Only

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Engineering extracellular vesicles/exosomes for the treatment of ocular disease

Cardiff University Cardiff School of Optometry & Vision Sciences

Extracellular vesicles, also referred to as exosomes, are membrane‐bound particles containing huge numbers of proteins as well as genetic material in the form of RNA (mRNA and miRNA). Read more

Supervisor: Dr B Mead

5 August 2024 PhD Research Project Self-Funded PhD Students Only

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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology

More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more

Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson

Year round applications PhD Research Project Self-Funded PhD Students Only

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How do RNA-binding proteins control splice site selection? A multi-disciplinary approach

University of Leicester Molecular and Cell Biology

Almost every protein-coding gene in vertebrates can and does express multiple proteins. This is achieved primarily by RNA splicing, which is an essential step in gene expression in mammals and generates incredible diversity. Read more

Supervisors: Prof I Eperon, Prof A Hudson, Dr C Dominguez

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Supervisors: Dr M Young, Dr J Parker

Year round applications PhD Research Project Self-Funded PhD Students Only

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A sticky situation; determining the interplay between gastric mucus and the gastric microbiota using pre-cancerous organoids

University of Birmingham Institute of Microbiology and Infection

The gastrointestinal tract is lined by a layer of mucus, which serves as a barrier separating the microbiota and the underlying epithelial cell layer (Paone and Cani, 2020). Read more

Supervisors: Dr A Rossiter, Dr L Crouch

Year round applications PhD Research Project Self-Funded PhD Students Only

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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Greenwich School of Pharmacy (Medway Campus)

Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more

Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves

Year round applications PhD Research Project Self-Funded PhD Students Only

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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Kent Medway School of Pharmacy

Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more

Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves

Year round applications PhD Research Project Self-Funded PhD Students Only

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Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

University of Greenwich School of Pharmacy (Medway Campus)

The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more

Supervisors: Dr F Papagiannouli, Dr G Lall

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 175 gene expression PhD Projects, Programmes & Scholarships

gene expression PhD Projects, Programmes & Scholarships

We have 175 gene expression PhD Projects, Programmes & Scholarships

Fully funded PhD position on using genomics to inform climate smart resilience breeding in the marine finfish snapper (tāmure/Chrysophrys auratus)

Delineating the IRF6 regulatory network driving periderm formation and function

SLS SF1: Investigating the basis of invasive multi-drug resistant Salmonella Dublin

Exploring Molecular Pathways for Improved Neural Regeneration in Spinal Cord Injury

Molecular mechanisms of the increase in maximal aerobic capacity (VO2max) with regular exercise

Helminth products as macrophage “trainers”: a novel tool to induce anti-inflammatory trained immunity

Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

Engineering extracellular vesicles/exosomes for the treatment of ocular disease

Structural investigation of oncogenic splicing factors

How do RNA-binding proteins control splice site selection? A multi-disciplinary approach

Investigating the role of P2X7 receptor intracellular domains in cell signalling

A sticky situation; determining the interplay between gastric mucus and the gastric microbiota using pre-cancerous organoids

Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

We have 175 gene expression PhD Projects, Programmes & Scholarships

gene expression PhD Projects, Programmes & Scholarships

We have 175 gene expression PhD Projects, Programmes & Scholarships

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